Loperamide System Suitability Mixture

NA

4-(4-Chlorophenyl)piperidin-4-ol and 4-(4-Hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide; 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamidehydrochloride and (1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbutyl]-4-hydroxypiperidine 1-oxide and (1s,4r)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbutyl]-4-hydroxypiperidine 1-oxide and 4-[4-(4-Chlorophenyl)-5,6-dihydropyridin-1(2H)-yl]-N,N-dimethyl-2,2-diphenylbutanamide and 1,4-Bis[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutan-1-one and 4-[4-(4′-Chlorobiphenyl-4-yl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl2,2-diphenylbutanamide and 4-(4-Chlorophenyl)-1,1-bis[4-(dimethylamino)-4-oxo-3,3-diphenylbutyl]-4-hydroxypiperidin-1-iumchloride; This is a mixture containing loperamide hydrochloride as the major component, and minor componentschlorophenylpiperidinol, deschloroloperamide, loperamide trans-N-oxide, loperamide cis-N-oxide,anhydroloperamide,loperamide piperidinolamide, loperamide biphenyl analog and loperamide quarternary salt (USP);