| Catalogue number: | PA STI 074200 |
| Chemical name: | Pitavastatin-d5 Lactone |
CAS Number: |
NA |
| Category: | aromatics,chiral standards,enzyme inhibitors,stable isotopes,metabolites,impurities,pharmaceutical standards,intermediates,fine chemicals |
| Synonyms: | (4R,6S)-6-[(1E)-2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6β(E)]]-6-[2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5 (lactone); Nisvastatin-d5; P 872441-d5; |
| Molecular form: | C25H17D5FNO3 |
| Appearance: | Off-White to Pale Yellow Solid |
| Mol. Weight: | 408.48 |
| Storage: | 2-8°C Refrigerator,Under Inert Atmosphere |
| Shipping Conditions: | Ambient |
| Applications: | A labelled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells. |
| BTM: | NA |
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