Aficamten

Fine Chemicals - Aficamten is an investigational oral medication developed by Cytokinetics. It belongs to a class of drugs known as cardiac myosin inhibitors, and it is being developed specifically for the treatment of obstructive hypertrophic cardiomyopathy (HCM). Reference standards of Aficamten API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Aficamten
    [catalogue_number] => PA 01 4150000
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 337.38
    [form] => C18H19N5O2
    [cas] => 2364554-48-1
    [pslug] => 2364554-48-1-aficamten-pa014150000
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PA 01 4150000
PA 01 4150000

Aficamten

  • Catalogue No.:PA 01 4150000

  • CAS :

    2364554-48-1

  • Molecular Formula : C18H19N5O2

  • Molecular Weight : 337.38

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Details 
stdClass Object
(
    [pname] => (R)-1-Amino-2,3-dihydro-1H-indene-5-carbonitrile Hydrochloride
    [catalogue_number] => PA 01 4151000
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 194.66
    [form] => C10H11ClN2
    [cas] => 903556-00-3
    [pslug] => 903556-00-3-r-1-amino-2-3-dihydro-1h-indene-5-carbonitrile-hydrochloride-pa014151000
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PA 01 4151000
PA 01 4151000

(R)-1-Amino-2,3-dihydro-1H-indene-5-carbonitrile Hydrochloride

  • Catalogue No.:PA 01 4151000

  • CAS :

    903556-00-3

  • Molecular Formula : C10H11ClN2

  • Molecular Weight : 194.66

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Details 
stdClass Object
(
    [pname] => tert-Butyl (R)-(5-cyano-2,3-dihydro-1H-inden-1-yl)carbamate
    [catalogue_number] => PA 01 4151001
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 258.32
    [form] => C15H18N2O2
    [cas] => 903555-99-7
    [pslug] => 903555-99-7-tert-butyl-r-5-cyano-2-3-dihydro-1h-inden-1-yl-carbamate-pa014151001
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PA 01 4151001
PA 01 4151001

tert-Butyl (R)-(5-cyano-2,3-dihydro-1H-inden-1-yl)carbamate

  • Catalogue No.:PA 01 4151001

  • CAS :

    903555-99-7

  • Molecular Formula : C15H18N2O2

  • Molecular Weight : 258.32

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Details 
stdClass Object
(
    [pname] => tert-Butyl (R)-(5-bromo-2,3-dihydro-1H-inden-1-yl)carbamate
    [catalogue_number] => PA 01 4151002
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 312.21
    [form] => C14H18BrNO2
    [cas] => 903555-98-6
    [pslug] => 903555-98-6-tert-butyl-r-5-bromo-2-3-dihydro-1h-inden-1-yl-carbamate-pa014151002
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PA 01 4151002
PA 01 4151002

tert-Butyl (R)-(5-bromo-2,3-dihydro-1H-inden-1-yl)carbamate

  • Catalogue No.:PA 01 4151002

  • CAS :

    903555-98-6

  • Molecular Formula : C14H18BrNO2

  • Molecular Weight : 312.21

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Details 
stdClass Object
(
    [pname] => (R)-N-(5-Cyano-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide
    [catalogue_number] => PA 01 4141001
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 266.3
    [form] => C15H14N4O
    [cas] => 2364561-64-6
    [pslug] => 2364561-64-6-r-n-5-cyano-2-3-dihydro-1h-inden-1-yl-1-methyl-1h-pyrazole-4-carboxamide-pa014141001
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PA 01 4141001
PA 01 4141001

(R)-N-(5-Cyano-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide

  • Catalogue No.:PA 01 4141001

  • CAS :

    2364561-64-6

  • Molecular Formula : C15H14N4O

  • Molecular Weight : 266.3

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Details 
stdClass Object
(
    [pname] => (R)-1-Methyl-N-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1H-pyrazole-4-carboxamide
    [catalogue_number] => PA 01 4141002
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 323.36
    [form] => C17H17N5O2
    [cas] => 2364553-12-6
    [pslug] => 2364553-12-6-r-1-methyl-n-5-5-methyl-1-2-4-oxadiazol-3-yl-2-3-dihydro-1h-inden-1-yl-1h-pyrazole-4-carboxamide-pa014141002
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PA 01 4141002
PA 01 4141002

(R)-1-Methyl-N-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1H-pyrazole-4-carboxamide

  • Catalogue No.:PA 01 4141002

  • CAS :

    2364553-12-6

  • Molecular Formula : C17H17N5O2

  • Molecular Weight : 323.36

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Details 
stdClass Object
(
    [pname] => (R,Z)-N-(5-(N'-Hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide
    [catalogue_number] => PA 01 4141003
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 299.33
    [form] => C15H17N5O2
    [cas] => NA
    [pslug] => r-z-n-5-n-hydroxycarbamimidoyl-2-3-dihydro-1h-inden-1-yl-1-methyl-1h-pyrazole-4-carboxamide-pa014141003
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PA 01 4141003
PA 01 4141003

(R,Z)-N-(5-(N'-Hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide

  • Catalogue No.:PA 01 4141003

  • CAS :

    NA

  • Molecular Formula : C15H17N5O2

  • Molecular Weight : 299.33

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Details 
stdClass Object
(
    [pname] => (S)-N-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide
    [catalogue_number] => PA 01 4141004
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 337.38
    [form] => C18H19N5O2
    [cas] => NA
    [pslug] => s-n-5-5-ethyl-1-2-4-oxadiazol-3-yl-2-3-dihydro-1h-inden-1-yl-1-methyl-1h-pyrazole-4-carboxamide-pa014141004
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PA 01 4141004
PA 01 4141004

(S)-N-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide

  • Catalogue No.:PA 01 4141004

  • CAS :

    NA

  • Molecular Formula : C18H19N5O2

  • Molecular Weight : 337.38

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