Ambrisentan-Impurities | Pharmaffiliates

ambrisentan

Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. Reference standards of Ambrisentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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(
    [pname] => Ambrisentan Vinyloxy Impurity
    [catalogue_number] => PA 28 46550
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 302.37
    [form] => C20H18N2O
    [cas] => 1639429-81-4
    [pslug] => 1639429-81-4-ambrisentan-vinyloxy-impurity-pa2846550
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PA 28 46550

Ambrisentan Vinyloxy Impurity


  • Catalogue No.:PA 28 46550

  • CAS :

    1639429-81-4

  • Molecular Formula : C20H18N2O

  • Molecular Weight : 302.37

20% OFF
stdClass Object
(
    [pname] => (R)-Ambrisentan
    [catalogue_number] => PA 28 46560
    [category_ids] => ,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 378.16
    [form] => C22H22N2O4
    [cas] => 1007358-76-0
    [pslug] => 1007358-76-0-r-ambrisentan-pa2846560
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PA 28 46560

(R)-Ambrisentan


  • Catalogue No.:PA 28 46560

  • CAS :

    1007358-76-0

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.16

stdClass Object
(
    [pname] => 3,3-Diphenyl-oxiranecarboxylic Acid Methyl Ester
    [catalogue_number] => PA 28 46570
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 254.28
    [form] => C16H14O3
    [cas] => 76527-25-8
    [pslug] => 76527-25-8-3-3-diphenyl-oxiranecarboxylic-acid-methyl-ester-pa2846570
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PA 28 46570

3,3-Diphenyl-oxiranecarboxylic Acid Methyl Ester


  • Catalogue No.:PA 28 46570

  • CAS :

    76527-25-8

  • Molecular Formula : C16H14O3

  • Molecular Weight : 254.28

stdClass Object
(
    [pname] => rac Ambrisentan-d3
    [catalogue_number] => PA STI 005030
    [category_ids] => ,80,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 381.44
    [form] => C22H19D3N2O4
    [cas] => 1189479-60-4
    [pslug] => 1189479-60-4-rac-ambrisentan-d3-pasti005030
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PA STI 005030

rac Ambrisentan-d3


  • Catalogue No.:PA STI 005030

  • CAS :

    1189479-60-4

  • Molecular Formula : C22H19D3N2O4

  • Molecular Weight : 381.44

stdClass Object
(
    [pname] => rac Ambrisentan-d3 Methyl Ester
    [catalogue_number] => PA STI 005040
    [category_ids] => ,80,78,70,82,98,
    [chemical_name] => 
    [weight] => 395.47
    [form] => C23H21D3N2O4
    [cas] => 1329837-75-3
    [pslug] => 1329837-75-3-rac-ambrisentan-d3-methyl-ester-pasti005040
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PA STI 005040

rac Ambrisentan-d3 Methyl Ester


  • Catalogue No.:PA STI 005040

  • CAS :

    1329837-75-3

  • Molecular Formula : C23H21D3N2O4

  • Molecular Weight : 395.47

stdClass Object
(
    [pname] => 4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan-d5
    [catalogue_number] => PA STI 033300
    [category_ids] => ,80,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 415.45
    [form] => C22H17D5N2O6
    [cas] => 1346597-40-7
    [pslug] => 1346597-40-7-4-6-dimethoxy-beta-methyl-3-phenoxy-ambrisentan-d5-pasti033300
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PA STI 033300

4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan-d5


  • Catalogue No.:PA STI 033300

  • CAS :

    1346597-40-7

  • Molecular Formula : C22H17D5N2O6

  • Molecular Weight : 415.45

stdClass Object
(
    [pname] => 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid-d3 Methyl Ester
    [catalogue_number] => PA STI 049730
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 289.34
    [form] => C17H15D3O4
    [cas] => 1046116-52-2
    [pslug] => 1046116-52-2-2-hydroxy-3-methoxy-3-3-diphenylpropanoic-acid-d3-methyl-ester-pasti049730
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PA STI 049730

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid-d3 Methyl Ester


  • Catalogue No.:PA STI 049730

  • CAS :

    1046116-52-2

  • Molecular Formula : C17H15D3O4

  • Molecular Weight : 289.34

stdClass Object
(
    [pname] => rac 4-Hydroxymethyl Ambrisentan-d3
    [catalogue_number] => PA STI 050030
    [category_ids] => ,80,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 397.44
    [form] => C22H19D3N2O5
    [cas] =>  1287096-42-7
    [pslug] => 1287096-42-7-rac-4-hydroxymethyl-ambrisentan-d3-pasti050030
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PA STI 050030

rac 4-Hydroxymethyl Ambrisentan-d3


  • Catalogue No.:PA STI 050030

  • CAS :

    1287096-42-7

  • Molecular Formula : C22H19D3N2O5

  • Molecular Weight : 397.44

stdClass Object
(
    [pname] => rac Ambrisentan Methyl Ester
    [catalogue_number] => PA 28 46600
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 392.45
    [form] => C23H24N2O4
    [cas] => 1240470-84-1
    [pslug] => 1240470-84-1-rac-ambrisentan-methyl-ester-pa2846600
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PA 28 46600

rac Ambrisentan Methyl Ester


  • Catalogue No.:PA 28 46600

  • CAS :

    1240470-84-1

  • Molecular Formula : C23H24N2O4

  • Molecular Weight : 392.45

stdClass Object
(
    [pname] => Ambrisentan Acyl β-D-Glucuronide
    [catalogue_number] => PA 28 46610
    [category_ids] => ,80,95,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 554.55
    [form] => C28H30N20O10
    [cas] => 1106685-58-8
    [pslug] => 1106685-58-8-ambrisentan-acyl-beta-d-glucuronide-pa2846610
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PA 28 46610

Ambrisentan Acyl β-D-Glucuronide


  • Catalogue No.:PA 28 46610

  • CAS :

    1106685-58-8

  • Molecular Formula : C28H30N20O10

  • Molecular Weight : 554.55

stdClass Object
(
    [pname] => Ambrisentan Pyrimidine Ester Impurity
    [catalogue_number] => PA 28 46620
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 392.46
    [form] => C23H24N2O4
    [cas] => NA
    [pslug] => ambrisentan-pyrimidine-ester-impurity-pa2846620
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PA 28 46620

Ambrisentan Pyrimidine Ester Impurity


  • Catalogue No.:PA 28 46620

  • CAS :

    NA

  • Molecular Formula : C23H24N2O4

  • Molecular Weight : 392.46

stdClass Object
(
    [pname] => 2,3-Dihydroxy-3,3-diphenylpropionic Acid Methyl Ester
    [catalogue_number] => PA 28 0461000
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 272.3
    [form] => C16H16O4
    [cas] => NA
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PA 28 0461000

2,3-Dihydroxy-3,3-diphenylpropionic Acid Methyl Ester


  • Catalogue No.:PA 28 0461000

  • CAS :

    NA

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.3

stdClass Object
(
    [pname] => (R,S)-Ambrisentan acyl-β-D-glucuronide
    [catalogue_number] => PA 28 0461002
    [category_ids] => ,70,75,76,78,82,95,
    [chemical_name] => 
    [weight] => 554.55
    [form] => C28H30N2O10
    [cas] => 1106685-82-8
    [pslug] => 1106685-82-8-r-s-ambrisentan-acyl-beta-d-glucuronide-pa280461002
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PA 28 0461002

(R,S)-Ambrisentan acyl-β-D-glucuronide


  • Catalogue No.:PA 28 0461002

  • CAS :

    1106685-82-8

  • Molecular Formula : C28H30N2O10

  • Molecular Weight : 554.55

stdClass Object
(
    [pname] => Ambrisentan Hydroxy Acid Impurity (R-Isomer)
    [catalogue_number] => PA 28 0461003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 272.3
    [form] => C16H16O4
    [cas] => 178306-49-5
    [pslug] => 178306-49-5-ambrisentan-hydroxy-acid-impurity-r-isomer-pa280461003
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PA 28 0461003

Ambrisentan Hydroxy Acid Impurity (R-Isomer)


  • Catalogue No.:PA 28 0461003

  • CAS :

    178306-49-5

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.3

stdClass Object
(
    [pname] => rac 4-Hydroxymethyl Ambrisentan
    [catalogue_number] => PA 28 0461004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 394.43
    [form] => C22H22N2O5
    [cas] => 1106685-84-0
    [pslug] => 1106685-84-0-rac-4-hydroxymethyl-ambrisentan-pa280461004
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PA 28 0461004

rac 4-Hydroxymethyl Ambrisentan


  • Catalogue No.:PA 28 0461004

  • CAS :

    1106685-84-0

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

stdClass Object
(
    [pname] => Ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate
    [catalogue_number] => PA 28 0461005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 406.48
    [form] => C24H26N2O4
    [cas] => 1349854-31-4
    [pslug] => 1349854-31-4-ethyl-s-2-4-6-dimethylpyrimidin-2-yl-oxy-3-methoxy-3-3-diphenylpropanoate-pa280461005
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PA 28 0461005

Ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate


  • Catalogue No.:PA 28 0461005

  • CAS :

    1349854-31-4

  • Molecular Formula : C24H26N2O4

  • Molecular Weight : 406.48

stdClass Object
(
    [pname] => 2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ethyl ester
    [catalogue_number] => PA 28 0461006
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    [chemical_name] => 
    [weight] => 406.48
    [form] => C24H26N2O4
    [cas] => NA
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PA 28 0461006

2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ethyl ester


  • Catalogue No.:PA 28 0461006

  • CAS :

    NA

  • Molecular Formula : C24H26N2O4

  • Molecular Weight : 406.48

stdClass Object
(
    [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid
    [catalogue_number] => PA 28 0461007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 346.39
    [form] => C21H18N2O3
    [cas] => 1312092-82-2
    [pslug] => 1312092-82-2-2-4-6-dimethylpyrimidin-2-yl-oxy-3-3-diphenylacrylic-acid-pa280461007
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PA 28 0461007

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid


  • Catalogue No.:PA 28 0461007

  • CAS :

    1312092-82-2

  • Molecular Formula : C21H18N2O3

  • Molecular Weight : 346.39

stdClass Object
(
    [pname] => Ambrisentan N-Oxide
    [catalogue_number] => PA 28 0461008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 394.43
    [form] => C22H22N2O5
    [cas] => NA
    [pslug] => ambrisentan-n-oxide-pa280461008
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PA 28 0461008

Ambrisentan N-Oxide


  • Catalogue No.:PA 28 0461008

  • CAS :

    NA

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

stdClass Object
(
    [pname] => (S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
    [catalogue_number] => PA STI 088903
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 397.45
    [form] => C22H19D3N2O5
    [cas] => NA
    [pslug] => s-2-4-hydroxymethyl-6-methyl-d3-pyrimidin-2-yl-oxy-3-methoxy-3-3-diphenylpropanoic-acid-pasti088903
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PA STI 088903

(S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid


  • Catalogue No.:PA STI 088903

  • CAS :

    NA

  • Molecular Formula : C22H19D3N2O5

  • Molecular Weight : 397.45

stdClass Object
(
    [pname] => Ambrisentan D3
    [catalogue_number] => PA STI 088904
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 381.45
    [form] => C22H19D3N2O4
    [cas] => 1046116-26-0
    [pslug] => 1046116-26-0-ambrisentan-d3-pasti088904
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PA STI 088904

Ambrisentan D3


  • Catalogue No.:PA STI 088904

  • CAS :

    1046116-26-0

  • Molecular Formula : C22H19D3N2O4

  • Molecular Weight : 381.45

stdClass Object
(
    [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1-phenylethan-1-one
    [catalogue_number] => PAI 01 016041
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 242.28
    [form] => C14H14N2O2
    [cas] => 2052996-29-7
    [pslug] => 2052996-29-7-2-4-6-dimethylpyrimidin-2-yl-oxy-1-phenylethan-1-one-pai01016041
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PAI 01 016041

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1-phenylethan-1-one


  • Catalogue No.:PAI 01 016041

  • CAS :

    2052996-29-7

  • Molecular Formula : C14H14N2O2

  • Molecular Weight : 242.28

stdClass Object
(
    [pname] => 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1,1-diphenylethan-1-ol
    [catalogue_number] => PAI 01 016042
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 320.39
    [form] => C20H20N2O2
    [cas] => 2052996-28-6
    [pslug] => 2052996-28-6-2-4-6-dimethylpyrimidin-2-yl-oxy-1-1-diphenylethan-1-ol-pai01016042
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PAI 01 016042

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1,1-diphenylethan-1-ol


  • Catalogue No.:PAI 01 016042

  • CAS :

    2052996-28-6

  • Molecular Formula : C20H20N2O2

  • Molecular Weight : 320.39

stdClass Object
(
    [pname] => Diphenylacetaldehyde
    [catalogue_number] => PA 28 0461009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 196.25
    [form] => C14H12O
    [cas] => 947-91-1
    [pslug] => 947-91-1-diphenylacetaldehyde-pa280461009
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PA 28 0461009

Diphenylacetaldehyde


  • Catalogue No.:PA 28 0461009

  • CAS :

    947-91-1

  • Molecular Formula : C14H12O

  • Molecular Weight : 196.25

stdClass Object
(
    [pname] => 4-Hydroxymethyl Ambrisentan D5
    [catalogue_number] => PA STI 089231
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 399.46
    [form] => C22H17D5N2O5
    [cas] => 2012598-50-2
    [pslug] => 2012598-50-2-4-hydroxymethyl-ambrisentan-d5-pasti089231
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PA STI 089231

4-Hydroxymethyl Ambrisentan D5


  • Catalogue No.:PA STI 089231

  • CAS :

    2012598-50-2

  • Molecular Formula : C22H17D5N2O5

  • Molecular Weight : 399.46

stdClass Object
(
    [pname] => Rac O-Demethyl Ambrisentan
    [catalogue_number] => PA 28 0461010
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 364.4
    [form] => C21H20N2O4
    [cas] => NA
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PA 28 0461010

Rac O-Demethyl Ambrisentan


  • Catalogue No.:PA 28 0461010

  • CAS :

    NA

  • Molecular Formula : C21H20N2O4

  • Molecular Weight : 364.4