cyclosporin
Fine Chemicals
- Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product. It is approved by the FDA to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants.. Reference standards of Cyclosporin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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[pname] => Cyclosporin
[catalogue_number] => PA 03 84000
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[chemical_name] =>
[weight] => 1202.61
[form] => C62H111N11O12
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Catalogue No.:PA 03 84000
Molecular Formula : C62H111N11O12
Molecular Weight : 1202.61
stdClass Object
(
[pname] => Cyclosporin - Impurity B
[catalogue_number] => PA 03 84010
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[weight] => 1204.63
[form] => C62H113N11O12
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Catalogue No.:PA 03 84010
Molecular Formula : C62H113N11O12
Molecular Weight : 1204.63
stdClass Object
(
[pname] => Cyclosporin B
[catalogue_number] => PA 03 84020
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1188.58
[form] => C61H109N11O12
[cas] => 63775-95-1
[pslug] => 63775-95-1-cyclosporin-b-pa0384020
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Catalogue No.:PA 03 84020
Molecular Formula : C61H109N11O12
Molecular Weight : 1188.58
stdClass Object
(
[pname] => Cyclosporin C
[catalogue_number] => PA 03 84030
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1218.64
[form] => C62H111N11O13
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Catalogue No.:PA 03 84030
Molecular Formula : C62H111N11O13
Molecular Weight : 1218.64
stdClass Object
(
[pname] => Cyclosporin D
[catalogue_number] => PA 03 84040
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1216.64
[form] => C63H113N11O12
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Catalogue No.:PA 03 84040
Molecular Formula : C63H113N11O12
Molecular Weight : 1216.64
stdClass Object
(
[pname] => Cyclosporin H
[catalogue_number] => PA 03 84080
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[chemical_name] =>
[weight] => 1202.63
[form] => C62H111N11O12
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Catalogue No.:PA 03 84080
Molecular Formula : C62H111N11O12
Molecular Weight : 1202.63
stdClass Object
(
[pname] => Cyclosporin - Impurity C
[catalogue_number] => PA 03 84510
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1202.61
[form] => C62H111N11O12
[cas] => 59865-16-6
[pslug] => 59865-16-6-isociclosporin-a-impurity-c-pa0384510
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Catalogue No.:PA 03 84510
Molecular Formula : C62H111N11O12
Molecular Weight : 1202.61
stdClass Object
(
[pname] => Cyclosporin G
[catalogue_number] => PA 03 84520
[category_ids] => ,70,78,79,82,114,
[chemical_name] =>
[weight] => 1216.64
[form] => C63H113N11O12
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Catalogue No.:PA 03 84520
Molecular Formula : C63H113N11O12
Molecular Weight : 1216.64
stdClass Object
(
[pname] => Cyclosporine Resolution Mixture
[catalogue_number] => PA 03 84530
[category_ids] => ,70,78,79,82,114,
[chemical_name] =>
[weight] => 1188.58
[form] => C61H109N11O12
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Cyclosporine Resolution Mixture
Catalogue No.:PA 03 84530
Molecular Formula : C61H109N11O12
Molecular Weight : 1188.58
stdClass Object
(
[pname] => Acetoxy Cyclosporin A Acetate
[catalogue_number] => PA 03 84540
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1302.7
[form] => C66H115N11O15
[cas] => 138957-23-0
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Acetoxy Cyclosporin A Acetate
Catalogue No.:PA 03 84540
Molecular Formula : C66H115N11O15
Molecular Weight : 1302.7
stdClass Object
(
[pname] => Iso Cyclosporin H Trifluoroacetic Acid Salt
[catalogue_number] => PA 03 84550
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1202.61 + x(114.02)
[form] => C62H111N11O12•x(C2HF3O2)
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Iso Cyclosporin H Trifluoroacetic Acid Salt
Catalogue No.:PA 03 84550
Molecular Formula : C62H111N11O12•x(C2HF3O2)
Molecular Weight : 1202.61 + x(114.02)
stdClass Object
(
[pname] => Cyclosporin A-d4 Acetate (Major)
[catalogue_number] => PA STI 023700
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[chemical_name] =>
[weight] => 1248.67
[form] => C64H109D4N11O13
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Cyclosporin A-d4 Acetate (Major)
Catalogue No.:PA STI 023700
Molecular Formula : C64H109D4N11O13
Molecular Weight : 1248.67
stdClass Object
(
[pname] => Cyclosporin A-13C2,d4 Acetate
[catalogue_number] => PA STI 023710
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[weight] => 1250.65
[form] => C6213C2H109D4N11O13
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Cyclosporin A-13C2,d4 Acetate
Catalogue No.:PA STI 023710
Molecular Formula : C6213C2H109D4N11O13
Molecular Weight : 1250.65
stdClass Object
(
[pname] => Cyclosporin A-13C2,d4 (Major)
[catalogue_number] => PA STI 023720
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[chemical_name] =>
[weight] => 1208.62
[form] => C6013C2H107D4N11O12
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[pslug] => cyclosporin-a-13c2-d4-major-
-pasti023720
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Cyclosporin A-13C2,d4 (Major)
Catalogue No.:PA STI 023720
Molecular Formula : C6013C2H107D4N11O12
Molecular Weight : 1208.62
stdClass Object
(
[pname] => Cyclosporin A-d4 (Major)
[catalogue_number] => PA STI 023730
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[weight] => 1206.64
[form] => C62H107D4N11O12
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Catalogue No.:PA STI 023730
Molecular Formula : C62H107D4N11O12
Molecular Weight : 1206.64
stdClass Object
(
[pname] => Cyclosporin B-d4
[catalogue_number] => PA STI 023740
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[chemical_name] =>
[weight] => 1192.58
[form] => C61H105D4N11O12
[cas] => NA
[pslug] => cyclosporin-b-d4-pasti023740
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Catalogue No.:PA STI 023740
Molecular Formula : C61H105D4N11O12
Molecular Weight : 1192.58
stdClass Object
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[pname] => Cyclosporin C-d4
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[weight] => 1222.64
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[cas] => NA
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Catalogue No.:PA STI 023750
Molecular Formula : C62H107D4N11O13
Molecular Weight : 1222.64
stdClass Object
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[pname] => Cyclosporin D-d4
[catalogue_number] => PA STI 023760
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[weight] => 1220.66
[form] => C63H109D4N11O12
[cas] => NA
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Catalogue No.:PA STI 023760
Molecular Formula : C63H109D4N11O12
Molecular Weight : 1220.66
stdClass Object
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[pname] => Cyclosporin H-d4
[catalogue_number] => PA STI 023770
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Catalogue No.:PA STI 023770
Molecular Formula : C62H107D4N11O12
Molecular Weight : 1206.64
stdClass Object
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[pname] => (3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
[catalogue_number] => PA 03 84590
[category_ids] => ,70,78,82,114,
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[weight] => 1321.82
[form] => C66H120N12O13S
[cas] => 210759-10-7
[pslug] => 210759-10-7-3s-6s-9s-12r-15s-18s-21s-24s-27r-30s-33s-27-2-dimethylamino-ethyl-thio-30-ethyl-33-1r-2r-e-1-hydroxy-2-methylhex-4-en-1-yl-24-2-hydroxy-2-methylpropyl-6-9-18-triisobutyl-3-21-diisopropyl-1-4-7-10-12-15-19-25-28-nonamethyl-1-4-7-10-13-16-19-22-25-28-31-undecaazacyclotritriacontan-2-5-8-11-14-17-20-23-26-29-32-undecaone-pa0384590
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(3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-27-((2-(Dimethylamino)ethyl)thio)-30-ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-24-(2-hydroxy-2-methylpropyl)-6,9,18-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
Catalogue No.:PA 03 84590
Molecular Formula : C66H120N12O13S
Molecular Weight : 1321.82
stdClass Object
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[pname] => Abu 5-Cyclosporin
[catalogue_number] => PA 03 0841000
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[weight] => 1188.61
[form] => C61H109N11O12
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Catalogue No.:PA 03 0841000
Molecular Formula : C61H109N11O12
Molecular Weight : 1188.61
stdClass Object
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[pname] => (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-15,30-Diethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
[catalogue_number] => PA 03 0841001
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[chemical_name] =>
[weight] => 1216.66
[form] => C63H113N11O12
[cas] => NA
[pslug] => 3s-6s-9s-12r-15s-18s-21s-24s-30s-33s-15-30-diethyl-33-1r-2r-e-1-hydroxy-2-methylhex-4-en-1-yl-6-9-18-24-tetraisobutyl-3-21-diisopropyl-1-4-7-10-12-19-25-28-octamethyl-1-4-7-10-13-16-19-22-25-28-31-undecaazacyclotritriacontan-2-5-8-11-14-17-20-23-26-29-32-undecaone-pa030841001
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(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-15,30-Diethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,19,25,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
Catalogue No.:PA 03 0841001
Molecular Formula : C63H113N11O12
Molecular Weight : 1216.66
stdClass Object
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[catalogue_number] => PA 03 0841003
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[weight] => 183.18
[form] => C7H14NNaO3
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Sodium 4-hydroxy-4-methyl-2-(methylamino)pentanoate
Catalogue No.:PA 03 0841003
Molecular Formula : C7H14NNaO3
Molecular Weight : 183.18
stdClass Object
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[pname] => Cyclosporin - Impurity G
[catalogue_number] => PA 03 0840070
[category_ids] => ,70,75,76,78,82,114,
[chemical_name] =>
[weight] => NA
[form] => NA
[cas] => 63775-96-2
[pslug] => 63775-96-2-cyclosporin-impurity-g-pa030840070
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(
[pname] => Cyclosporin - Impurity E
[catalogue_number] => PA 03 0840050
[category_ids] => ,70,75,76,78,82,114,
[chemical_name] =>
[weight] => 1216.66
[form] => C63H113N11O12
[cas] => 108027-46-9
[pslug] => 108027-46-9-cyclosporin-impurity-e-pa030840050
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Catalogue No.:PA 03 0840050
Molecular Formula : C63H113N11O12
Molecular Weight : 1216.66
stdClass Object
(
[pname] => Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)
[catalogue_number] => PA 03 0841004
[category_ids] => ,70,75,76,78,82,114,
[chemical_name] =>
[weight] => 1218.63
[form] => C62H111N11O13
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Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)
Catalogue No.:PA 03 0841004
Molecular Formula : C62H111N11O13
Molecular Weight : 1218.63
stdClass Object
(
[pname] => Cyclosporin - Impurity F
[catalogue_number] => PA 03 0840060
[category_ids] => ,114,97,82,78,76,75,
[chemical_name] =>
[weight] => 1202.64
[form] => C62H111N11O12
[cas] => NA
[pslug] => cyclosporin-impurity-f-pa030840060
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Catalogue No.:PA 03 0840060
Molecular Formula : C62H111N11O12
Molecular Weight : 1202.64
stdClass Object
(
[pname] => Cyclosporin Q
[catalogue_number] => PA 03 0841005
[category_ids] => ,70,75,76,78,82,114,
[chemical_name] =>
[weight] => 1174.58
[form] => C60H107N11O12
[cas] => 108027-42-5
[pslug] => 108027-42-5-cyclosporin-q-pa030841005
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Catalogue No.:PA 03 0841005
Molecular Formula : C60H107N11O12
Molecular Weight : 1174.58
stdClass Object
(
[pname] => Dihydrocyclosporin H
[catalogue_number] => PA 03 0841006
[category_ids] => ,70,75,76,78,82,114,
[chemical_name] =>
[weight] => 1204.65
[form] => C62H113N11O12
[cas] => 83602-88-4
[pslug] => 83602-88-4-dihydrocyclosporin-h-pa030841006
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Catalogue No.:PA 03 0841006
Molecular Formula : C62H113N11O12
Molecular Weight : 1204.65
stdClass Object
(
[pname] => Cyclosporin AM 1
[catalogue_number] => PA 03 0841007
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[weight] => 1218.63
[form] => C62H111N11O13
[cas] => 89270-28-0
[pslug] => 89270-28-0-cyclosporin-am-1-pa030841007
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Catalogue No.:PA 03 0841007
Molecular Formula : C62H111N11O13
Molecular Weight : 1218.63
stdClass Object
(
[pname] => Cyclosporin - Impurity D
[catalogue_number] => PA 03 0840040
[category_ids] => ,70,75,76,78,82,114,
[chemical_name] =>
[weight] => 1188.61
[form] => C61H109N11O12
[cas] => 108027-45-8
[pslug] => 108027-45-8-cyclosporin-impurity-d-pa030840040
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Catalogue No.:PA 03 0840040
Molecular Formula : C61H109N11O12
Molecular Weight : 1188.61
stdClass Object
(
[pname] => Cyclosporin T
[catalogue_number] => PA 03 0841008
[category_ids] => ,70,75,76,78,82,114,
[chemical_name] =>
[weight] => 1188.61
[form] => C61H109N11O12
[cas] => 108027-44-7
[pslug] => 108027-44-7-cyclosporin-t-pa030841008
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Catalogue No.:PA 03 0841008
Molecular Formula : C61H109N11O12
Molecular Weight : 1188.61
stdClass Object
(
[pname] => (4S,5R)-5-((R,E)-Hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-5,8,10,13,17,23,26-heptamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide
[catalogue_number] => PA 03 0841009
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1146.53
[form] => C58H103N11O12
[cas] => 1907654-63-0
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(4S,5R)-5-((R,E)-Hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-5,8,10,13,17,23,26-heptamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide
Catalogue No.:PA 03 0841009
Molecular Formula : C58H103N11O12
Molecular Weight : 1146.53
stdClass Object
(
[pname] => 6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A
[catalogue_number] => PA 03 0841010
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 1232.62
[form] => C62H109N11O14
[cas] => 121584-52-9
[pslug] => 121584-52-9-6-3r-4r-3-acetyloxy-n-4-dimethyl-6-oxo-l-norleucine-cyclosporin-a-pa030841010
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6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A
Catalogue No.:PA 03 0841010
Molecular Formula : C62H109N11O14
Molecular Weight : 1232.62
stdClass Object
(
[pname] => Benzyl (S)-N-(2-((tert-butoxycarbonyl)amino)pentanoyl)-N-methylglycinate
[catalogue_number] => PAI 03 038035
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 378.47
[form] => C20H30N2O5
[cas] => NA
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Benzyl (S)-N-(2-((tert-butoxycarbonyl)amino)pentanoyl)-N-methylglycinate
Catalogue No.:PAI 03 038035
Molecular Formula : C20H30N2O5
Molecular Weight : 378.47
stdClass Object
(
[pname] => (S)-N-(2-((tert-Butoxycarbonyl)amino)pentanoyl)-N-methylglycine
[catalogue_number] => PAI 03 038036
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 288.34
[form] => C13H24N2O5
[cas] => NA
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(S)-N-(2-((tert-Butoxycarbonyl)amino)pentanoyl)-N-methylglycine
Catalogue No.:PAI 03 038036
Molecular Formula : C13H24N2O5
Molecular Weight : 288.34
stdClass Object
(
[pname] => Benzyl N-(tert-butoxycarbonyl)-N-methyl-L-leucyl-L-alaninate
[catalogue_number] => PAI 03 038037
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 406.52
[form] => C22H34N2O5
[cas] => 81135-24-2
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Benzyl N-(tert-butoxycarbonyl)-N-methyl-L-leucyl-L-alaninate
Catalogue No.:PAI 03 038037
Molecular Formula : C22H34N2O5
Molecular Weight : 406.52
stdClass Object
(
[pname] => Benzyl methyl-L-leucyl-L-alaninate
[catalogue_number] => PAI 03 038038
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 306.41
[form] => C17H26N2O3
[cas] => 81135-25-3
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Benzyl methyl-L-leucyl-L-alaninate
Catalogue No.:PAI 03 038038
Molecular Formula : C17H26N2O3
Molecular Weight : 306.41
stdClass Object
(
[pname] => Benzyl N-((tert-butoxycarbonyl)-L-valyl)-N-methyl-L-leucyl-L-alaninate
[catalogue_number] => PAI 03 038039
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 505.66
[form] => C27H43N3O6
[cas] => 81135-26-4
[pslug] => 81135-26-4-benzyl-n-tert-butoxycarbonyl-l-valyl-n-methyl-l-leucyl-l-alaninate-pai03038039
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Benzyl N-((tert-butoxycarbonyl)-L-valyl)-N-methyl-L-leucyl-L-alaninate
Catalogue No.:PAI 03 038039
Molecular Formula : C27H43N3O6
Molecular Weight : 505.66
stdClass Object
(
[pname] => Benzyl N-(L-valyl)-N-methyl-L-leucyl-L-alaninate
[catalogue_number] => PAI 03 038040
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 405.54
[form] => C22H35N3O4
[cas] => 81135-27-5
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Benzyl N-(L-valyl)-N-methyl-L-leucyl-L-alaninate
Catalogue No.:PAI 03 038040
Molecular Formula : C22H35N3O4
Molecular Weight : 405.54
stdClass Object
(
[pname] => Benzyl N-N-(tert-butoxycarbonyl)-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alaninate
[catalogue_number] => PAI 03 038041
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 632.84
[form] => C34H56N4O7
[cas] => 81143-02-4
[pslug] => 81143-02-4-benzyl-n-n-tert-butoxycarbonyl-n-methyl-l-leucyl-l-valyl-n-methyl-l-leucyl-l-alaninate-pai03038041
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Benzyl N-N-(tert-butoxycarbonyl)-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alaninate
Catalogue No.:PAI 03 038041
Molecular Formula : C34H56N4O7
Molecular Weight : 632.84
stdClass Object
(
[pname] => Benzyl N-methyl-N-methyl-L-leucyl-L-valyl-L-leucyl-L-alaninate
[catalogue_number] => PAI 03 038042
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[chemical_name] =>
[weight] => 532.73
[form] => C29H48N4O5
[cas] => 81135-28-6
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Benzyl N-methyl-N-methyl-L-leucyl-L-valyl-L-leucyl-L-alaninate
Catalogue No.:PAI 03 038042
Molecular Formula : C29H48N4O5
Molecular Weight : 532.73
stdClass Object
(
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[catalogue_number] => PAI 03 038043
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 350.42
[form] => C18H26N2O5
[cas] => 133499-51-1
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Benzyl N-((tert-butoxycarbonyl)-L-alanyl)-N-methylglycinate
Catalogue No.:PAI 03 038043
Molecular Formula : C18H26N2O5
Molecular Weight : 350.42
stdClass Object
(
[pname] => N-((tert-Butoxycarbonyl)-L-alanyl)-N-methylglycine
[catalogue_number] => PAI 03 038044
[category_ids] => ,70,78,82,93,97,114,
[chemical_name] =>
[weight] => 260.29
[form] => C11H20N2O5
[cas] => 126307-30-0
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N-((tert-Butoxycarbonyl)-L-alanyl)-N-methylglycine
Catalogue No.:PAI 03 038044
Molecular Formula : C11H20N2O5
Molecular Weight : 260.29
stdClass Object
(
[pname] => N-(N-(N-((tert-Butoxycarbonyl)-D-alanyl)-N-methyl-L-leucyl)-N-methyl-L-leucyl)-N-methyl-D-valine
[catalogue_number] => PA 03 0841011
[category_ids] => ,70,78,82,114,
[chemical_name] =>
[weight] => 556.75
[form] => C28H52N4O7
[cas] => 89536-98-1
[pslug] => 89536-98-1-n-n-n-tert-butoxycarbonyl-d-alanyl-n-methyl-l-leucyl-n-methyl-l-leucyl-n-methyl-d-valine-pa030841011
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N-(N-(N-((tert-Butoxycarbonyl)-D-alanyl)-N-methyl-L-leucyl)-N-methyl-L-leucyl)-N-methyl-D-valine
Catalogue No.:PA 03 0841011
Molecular Formula : C28H52N4O7
Molecular Weight : 556.75
