eltrombopag
Fine Chemicals
- Eltrombopag is used to treat low blood platelet counts in adults with chronic immune thrombocytopenia when certain other medicines, or surgery to remove the spleen, have not worked well enough. It has been recently approved for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.. Reference standards of Eltrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
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[pname] => Eltrombopag
[catalogue_number] => PA 32 22000
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[weight] => 442.47
[form] => C25H22N4O4
[cas] => 496775-61-2
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Catalogue No.:PA 32 22000
Molecular Formula : C25H22N4O4
Molecular Weight : 442.47
stdClass Object
(
[pname] => Eltrombopag Amide
[catalogue_number] => PA 32 22510
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[weight] => 441.48
[form] => C25H23N5O3
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Catalogue No.:PA 32 22510
Molecular Formula : C25H23N5O3
Molecular Weight : 441.48
stdClass Object
(
[pname] => Eltrombopag Ethyl Ester
[catalogue_number] => PA 32 22520
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[chemical_name] =>
[weight] => 470.52
[form] => C27H26N4O4
[cas] => NA
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Catalogue No.:PA 32 22520
Molecular Formula : C27H26N4O4
Molecular Weight : 470.52
stdClass Object
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[pname] => Eltrombopag Methyl Ester
[catalogue_number] => PA 32 22530
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[chemical_name] =>
[weight] => 456.49
[form] => C26H24N4O4
[cas] => 1246929-01-0
[pslug] => 1246929-01-0-eltrombopag-methyl-ester-pa3222530
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Catalogue No.:PA 32 22530
Molecular Formula : C26H24N4O4
Molecular Weight : 456.49
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[catalogue_number] => PA 32 22540
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[weight] => 492.91
[form] => C25H21ClN4O5
[cas] => NA
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(E)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)-1-hydroxyhydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 22540
Molecular Formula : C25H21ClN4O5
Molecular Weight : 492.91
stdClass Object
(
[pname] => 1-(4-Ethoxyphenyl)-5-(2-hydroxy-4-methoxybenzoyl)pyridin-2(1H)-one
[catalogue_number] => PA 32 22550
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[weight] => 365.38
[form] => C21H19NO5
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1-(4-Ethoxyphenyl)-5-(2-hydroxy-4-methoxybenzoyl)pyridin-2(1H)-one
Catalogue No.:PA 32 22550
Molecular Formula : C21H19NO5
Molecular Weight : 365.38
stdClass Object
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[catalogue_number] => PA 32 22560
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(E)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 22560
Molecular Formula : C26H24N4O4
Molecular Weight : 456.49
stdClass Object
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[catalogue_number] => PA 32 22570
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(Z)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 22570
Molecular Formula : C25H21ClN4O4
Molecular Weight : 476.91
stdClass Object
(
[pname] => (Z)-2'-(Benzyloxy)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-[1,1'-biphenyl]-3-carboxylic Acid
[catalogue_number] => PA 32 22580
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[weight] => 532.59
[form] => C32H28N4O4
[cas] => NA
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(Z)-2'-(Benzyloxy)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 22580
Molecular Formula : C32H28N4O4
Molecular Weight : 532.59
stdClass Object
(
[pname] => Eltrombopag-13C4
[catalogue_number] => PA STI 036900
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[weight] => 446.44
[form] => C2113C4H22N4O4
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Catalogue No.:PA STI 036900
Molecular Formula : C2113C4H22N4O4
Molecular Weight : 446.44
stdClass Object
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[pname] => 3'-Amino-2'-Hydroxy-[1,1']biphenyl-3-carboxylic Acid
[catalogue_number] => PA 32 22590
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[weight] => 229.23
[form] => C13H11NO3
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3'-Amino-2'-Hydroxy-[1,1']biphenyl-3-carboxylic Acid
Catalogue No.:PA 32 22590
Molecular Formula : C13H11NO3
Molecular Weight : 229.23
stdClass Object
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[pname] => (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
[catalogue_number] => PA 32 0221000
[category_ids] => ,70,71,78,80,82,103,162,
[chemical_name] =>
[weight] => 471.47
[form] => C25H21N5O5
[cas] => NA
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(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Catalogue No.:PA 32 0221000
Molecular Formula : C25H21N5O5
Molecular Weight : 471.47
stdClass Object
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[pname] => 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
[catalogue_number] => PA 32 0221001
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[weight] => 202.26
[form] => C12H14N2O
[cas] => 277299-70-4
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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
Catalogue No.:PA 32 0221001
Molecular Formula : C12H14N2O
Molecular Weight : 202.26
stdClass Object
(
[pname] => 2-Aminoethyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylate
[catalogue_number] => PA 32 0221002
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[weight] => 499.57
[form] => C28H29N5O4
[cas] => NA
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2-Aminoethyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylate
Catalogue No.:PA 32 0221002
Molecular Formula : C28H29N5O4
Molecular Weight : 499.57
stdClass Object
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[pname] => 1-(3,4-Dimethylphenyl)-3-methyl-1H-pyrazol-5(4H)-one
[catalogue_number] => PA 32 0221003
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[weight] => 202.26
[form] => C12H14N2O
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1-(3,4-Dimethylphenyl)-3-methyl-1H-pyrazol-5(4H)-one
Catalogue No.:PA 32 0221003
Molecular Formula : C12H14N2O
Molecular Weight : 202.26
stdClass Object
(
[pname] => Eltrombopag lactose adduct
[catalogue_number] => PA 32 0221004
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[weight] => 766.76
[form] => C37H42N4O14
[cas] => NA
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Eltrombopag lactose adduct
Catalogue No.:PA 32 0221004
Molecular Formula : C37H42N4O14
Molecular Weight : 766.76
stdClass Object
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[weight] => 447.4
[form] => C21H21NO10
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(2S,3S,4S,5R)-6-((3-Acetamido-3'-carboxy-[1,1'-biphenyl]-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
stdClass Object
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[pname] => Methoxy Eltrombopag
[catalogue_number] => PA 32 0221006
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[chemical_name] =>
[weight] => 456.5
[form] => C26H24N4O4
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[catalogue_number] => PA 32 0221007
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[weight] => 485.54
[form] => C27H27N5O4
[cas] => NA
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(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-N-(2-hydroxyethyl)-[1,1'-biphenyl]-3-carboxamide
Catalogue No.:PA 32 0221007
Molecular Formula : C27H27N5O4
Molecular Weight : 485.54
stdClass Object
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[pname] => 2'-Hydroxybiphenyl-3-carboxylic Acid
[catalogue_number] => PA 32 0221009
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[weight] => 214.22
[form] => C13H10O3
[cas] => 893736-72-6
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2'-Hydroxybiphenyl-3-carboxylic Acid
Catalogue No.:PA 32 0221009
Molecular Formula : C13H10O3
Molecular Weight : 214.22
stdClass Object
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[pname] => Eltrombopag N-Oxide Impurity (E-Isomer)
[catalogue_number] => PA 32 0221008
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[weight] => 458.47
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Eltrombopag N-Oxide Impurity (E-Isomer)
Catalogue No.:PA 32 0221008
Molecular Formula : C25H22N4O5
Molecular Weight : 458.47
stdClass Object
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[form] => C13H9NO5
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2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221010
Molecular Formula : C13H9NO5
Molecular Weight : 259.22
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(E)-2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
Catalogue No.:PA 32 0221011
Molecular Formula : C12H13N3O2
Molecular Weight : 231.26
stdClass Object
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Eltrombopag N-Oxide Impurity (Z-Isomer)
Catalogue No.:PA 32 0221012
Molecular Formula : C25H22N4O5
Molecular Weight : 458.47
stdClass Object
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N-Nitroso Eltrombopag Amino Impurity
Catalogue No.:PA 32 0221013
Molecular Formula : C13H10N2O4
Molecular Weight : 258.23
stdClass Object
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3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221014
Molecular Formula : C25H22N4O4
Molecular Weight : 442.48
stdClass Object
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1,1'',2'-Tris(3,4-dimethylphenyl)-5,5''-dihydroxy-3,3'',5'-trimethyl-1H,1''H-[4,4':4',4''-terpyrazol]-3'(2'H)-one
Catalogue No.:PA 32 0221015
Molecular Formula : C36H38N6O3
Molecular Weight : 602.74
stdClass Object
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2-(2,3-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
Catalogue No.:PA 32 0221016
Molecular Formula : C12H14N2O
Molecular Weight : 202.26
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3,3'-(2-Amino-3-oxo-3H-phenoxazine-4,6-diyl)dibenzoic Acid
Catalogue No.:PA 32 0221017
Molecular Formula : C26H16N2O6
Molecular Weight : 452.42
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Eltrombopag dimer-1 impurity
stdClass Object
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2-(3,4-Dimethylphenyl)-5-methyl-1-nitroso-1,2-dihydro-3H-pyrazol-3-one
Catalogue No.:PA 32 0221019
Molecular Formula : C12H13N3O2
Molecular Weight : 231.26
stdClass Object
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(Z)-2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
Catalogue No.:PA 32 0221020
Molecular Formula : C12H13N3O2
Molecular Weight : 231.26
stdClass Object
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(Z)-2-(3,4-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one oxime
Catalogue No.:PA 32 0221022
Molecular Formula : C12H15N3O
Molecular Weight : 217.27
stdClass Object
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3'-(2-((4Z,5Z)-1-(3,4-Dimethylphenyl)-5-(hydroxyimino)-3-methyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221021
Molecular Formula : C25H23N5O4
Molecular Weight : 457.49
stdClass Object
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3'-Amino-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221023
Molecular Formula : C14H13NO3
Molecular Weight : 243.26
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(E)-2-(3,4-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one oxime
Catalogue No.:PA 32 0221024
Molecular Formula : C12H15N3O
Molecular Weight : 217.27
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2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
Catalogue No.:PA 32 0221025
Molecular Formula : C12H13N3O2
Molecular Weight : 231.26
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Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
stdClass Object
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(Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221027
Molecular Formula : C25H21N5O5
Molecular Weight : 471.47
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Catalogue No.:PA 32 0221028
Molecular Formula : C25H22N4O4
Molecular Weight : 442.48
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2'-Hydroxy-3'-(1-nitrosohydrazineyl)-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221029
Molecular Formula : C13H11N3O4
Molecular Weight : 273.25
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3'-Hydrazineyl-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221030
Molecular Formula : C13H12N2O3
Molecular Weight : 244.25
stdClass Object
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[weight] => 356.39
[form] => C21H16N4O2
[cas] => NA
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(Z)-4-(((E)-2-Hydroxy-[1,1'-biphenyl]-3(2H)-ylidene)hydrazineylidene)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
Catalogue No.:PA 32 0221031
Molecular Formula : C21H16N4O2
Molecular Weight : 356.39
stdClass Object
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[catalogue_number] => PA 32 0221032
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[weight] => 618.6
[form] => C31H30N4O10
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Eltrombopag Acyl Glucuronide
stdClass Object
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[catalogue_number] => PA 32 0221033
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[chemical_name] =>
[weight] => 400.39
[form] => C22H16N4O4
[cas] => NA
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(Z)-2'-Hydroxy-3'-(2-(5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221033
Molecular Formula : C22H16N4O4
Molecular Weight : 400.39
stdClass Object
(
[pname] => (Z)-3,4,5-Trihydroxy-6-((2'-hydroxy-3'-(1-hydroxy-2-(5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-[1,1'-biphenyl]-3-carbonyl)oxy)tetrahydro-2H-pyran-2-carboxylic Acid
[catalogue_number] => PA 32 0221034
[category_ids] => ,71,78,70,82,
[chemical_name] =>
[weight] => 516.42
[form] => C22H20N4O11
[cas] => NA
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(Z)-3,4,5-Trihydroxy-6-((2'-hydroxy-3'-(1-hydroxy-2-(5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-[1,1'-biphenyl]-3-carbonyl)oxy)tetrahydro-2H-pyran-2-carboxylic Acid
Catalogue No.:PA 32 0221034
Molecular Formula : C22H20N4O11
Molecular Weight : 516.42
stdClass Object
(
[pname] => Eltrombopag Olamine Ester
[catalogue_number] => PA 32 0221035
[category_ids] => ,71,78,70,82,
[chemical_name] =>
[weight] => 485.54
[form] => C27H27N5O4
[cas] => NA
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Eltrombopag Olamine Ester
Catalogue No.:PA 32 0221035
Molecular Formula : C27H27N5O4
Molecular Weight : 485.54
stdClass Object
(
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[catalogue_number] => PA 32 0221036
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 230.22
[form] => C13H10O4
[cas] => NA
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2',3'-Dihydroxy-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221036
Molecular Formula : C13H10O4
Molecular Weight : 230.22
stdClass Object
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[catalogue_number] => PA 32 0221037
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[weight] => 168.62
[form] => C8H9ClN2
[cas] => 69457-08-5
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3,4-Dimethylbenzenediazonium Chloride
Catalogue No.:PA 32 0221037
Molecular Formula : C8H9ClN2
Molecular Weight : 168.62
stdClass Object
(
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[catalogue_number] => PA 32 0221038
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[chemical_name] =>
[weight] => 349.34
[form] => C20H15NO5
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2'-(Benzyloxy)-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221038
Molecular Formula : C20H15NO5
Molecular Weight : 349.34
stdClass Object
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[weight] => 273.24
[form] => C14H11NO5
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2'-Methoxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid
Catalogue No.:PA 32 0221039
Molecular Formula : C14H11NO5
Molecular Weight : 273.24
stdClass Object
(
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[weight] => 272.26
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2'-Hydroxy-3'-(methyl(nitroso)amino)-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.:PA 32 0221040
Molecular Formula : C14H12N2O4
Molecular Weight : 272.26
stdClass Object
(
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[catalogue_number] => PA 32 0221041
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[weight] => 441.49
[form] => C25H23N5O3
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Eltrombopag Amide (E-Isomer)
Catalogue No.:PA 32 0221041
Molecular Formula : C25H23N5O3
Molecular Weight : 441.49
stdClass Object
(
[pname] => (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-N-(2-hydroxyethyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxamide
[catalogue_number] => PA 32 0221042
[category_ids] => ,103,80,71,78,70,82,
[chemical_name] =>
[weight] => 499.57
[form] => C28H29N5O4
[cas] => NA
[pslug] => z-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1-5-dihydro-4h-pyrazol-4-ylidene-hydrazineyl-n-2-hydroxyethyl-2-methoxy-1-1-biphenyl-3-carboxamide-pa320221042
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(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-N-(2-hydroxyethyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxamide
Catalogue No.:PA 32 0221042
Molecular Formula : C28H29N5O4
Molecular Weight : 499.57
stdClass Object
(
[pname] => 2-Aminoethyl (E)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
[catalogue_number] => PA 32 0221043
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[chemical_name] =>
[weight] => 485.54
[form] => C27H27N5O4
[cas] => NA
[pslug] => 2-aminoethyl-e-3-2-1-3-4-dimethylphenyl-3-methyl-5-oxo-1-5-dihydro-4h-pyrazol-4-ylidene-hydrazineyl-2-hydroxy-1-1-biphenyl-3-carboxylate-pa320221043
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2-Aminoethyl (E)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
Catalogue No.:PA 32 0221043
Molecular Formula : C27H27N5O4
Molecular Weight : 485.54
