gefitinib
Fine Chemicals
- Gefitinib is used to treat lung cancer. Acting in a similar manner to erlotinib gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. Reference standards of Gefitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Gefitinib
[catalogue_number] => PA 07 24000
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 446.90
[form] => C22H24ClFN4O3
[cas] => 184475-35-2
[pslug] => 184475-35-2-gefitinib-api-pa0724000
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Catalogue No.:PA 07 24000
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.90
stdClass Object
(
[pname] => Gefitinib - Impurity A
[catalogue_number] => PA 07 24010
[category_ids] => ,70,78,82,71,
[chemical_name] =>
[weight] => 319.36
[form] => C16H21N3O4
[cas] => 199327-61-2
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Catalogue No.:PA 07 24010
Molecular Formula : C16H21N3O4
Molecular Weight : 319.36
stdClass Object
(
[pname] => Gefitinib - Impurity B
[catalogue_number] => PA 07 24020
[category_ids] => ,82,80,79,78,71,70,
[chemical_name] =>
[weight] => 446.90
[form] => C22H24ClFN4O3
[cas] => 1603814-04-5
[pslug] => 1603814-04-5-gefitinib-impurity-b-pa0724020
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Catalogue No.:PA 07 24020
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.90
stdClass Object
(
[pname] => 3-Chloro-4-fluorophenylamine
[catalogue_number] => PA 07 24510
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 145.56
[form] => C6H5ClFN
[cas] => 367-21-5
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3-Chloro-4-fluorophenylamine
Catalogue No.:PA 07 24510
Molecular Formula : C6H5ClFN
Molecular Weight : 145.56
stdClass Object
(
[pname] => Gefitinib 4-Desfluoro Hydrochloride Impurity
[catalogue_number] => PA 07 24520
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 465.37
[form] => C22H26Cl2N4O3
[cas] => NA
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Gefitinib 4-Desfluoro Hydrochloride Impurity
Catalogue No.:PA 07 24520
Molecular Formula : C22H26Cl2N4O3
Molecular Weight : 465.37
stdClass Object
(
[pname] => Gefitinib N-Oxide
[catalogue_number] => PA 07 24530
[category_ids] => ,79,80,71,78,70,82,
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[weight] => 462.9
[form] => C22H24ClFN4O4
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stdClass Object
(
[pname] => O-Desmorpholinopropyl Gefitinib
[catalogue_number] => PA 07 24540
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 319.72
[form] => C15H11ClFN3O2
[cas] => 184475-71-6
[pslug] => 184475-71-6-o-desmorpholinopropyl-gefitinib-pa0724540
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O-Desmorpholinopropyl Gefitinib
Catalogue No.:PA 07 24540
Molecular Formula : C15H11ClFN3O2
Molecular Weight : 319.72
stdClass Object
(
[pname] => N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine
[catalogue_number] => PA 07 24550
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[weight] => 462.9
[form] => C22H24ClFN4O4
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N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine
stdClass Object
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[pname] => 4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide
[catalogue_number] => PA 07 24560
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[weight] => 478.9
[form] => C22H24ClFN4O5
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4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide
stdClass Object
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[pname] => N-(3-Morpholinopropyl) Gefitinib
[catalogue_number] => PA 07 24580
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[chemical_name] =>
[weight] => 574.09
[form] => C29H37ClFN5O4
[cas] => 1502829-45-9
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N-(3-Morpholinopropyl) Gefitinib
Catalogue No.:PA 07 24580
Molecular Formula : C29H37ClFN5O4
Molecular Weight : 574.09
stdClass Object
(
[pname] => N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
[catalogue_number] => PA 07 24590
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[weight] => 333.74
[form] => C16H13ClFN3O2
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N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Catalogue No.:PA 07 24590
Molecular Formula : C16H13ClFN3O2
Molecular Weight : 333.74
stdClass Object
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[pname] => N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 24600
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[weight] => 412.46
[form] => C22H25FN4O3
[cas] => 2254241-82-0
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N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24600
Molecular Formula : C22H25FN4O3
Molecular Weight : 412.46
stdClass Object
(
[pname] => 4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
[catalogue_number] => PA 07 24610
[category_ids] => ,82,78,76,75,70,
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[weight] => 337.8
[form] => C16H20ClN3O3
[cas] => 199327-59-8
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4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
stdClass Object
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[pname] => O-Desmethyl Gefitinib
[catalogue_number] => PA 07 24620
[category_ids] => ,76,75,78,70,82,
[chemical_name] =>
[weight] => 432.88
[form] => C21H22ClFN4O3
[cas] => 847949-49-9
[pslug] => 847949-49-9-o-desmethyl-gefitinib-pa0724620
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Catalogue No.:PA 07 24620
Molecular Formula : C21H22ClFN4O3
Molecular Weight : 432.88
stdClass Object
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[pname] => N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 24630
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[chemical_name] =>
[weight] => 430.45
[form] => C22H24F2N4O3
[cas] => 184475-50-1
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N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24630
Molecular Formula : C22H24F2N4O3
Molecular Weight : 430.45
stdClass Object
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[catalogue_number] => PA 07 24640
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[weight] => 444.91
[form] => C22H25ClN4O4
[cas] => 847949-50-2
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4-Defluoro-4-hydroxy Gefitinib
Catalogue No.:PA 07 24640
Molecular Formula : C22H25ClN4O4
Molecular Weight : 444.91
stdClass Object
(
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[catalogue_number] => PA 07 24650
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[weight] => 463.36
[form] => C22H24Cl2N4O3
[cas] => 2089650-13-3
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N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24650
Molecular Formula : C22H24Cl2N4O3
Molecular Weight : 463.36
stdClass Object
(
[pname] => 3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate
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[weight] => 362.74
[form] => C17H12ClFN2O4
[cas] => 2512211-98-0
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3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate
Catalogue No.:PA 07 24660
Molecular Formula : C17H12ClFN2O4
Molecular Weight : 362.74
stdClass Object
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[weight] => 447.89
[form] => C22H23ClFN3O4
[cas] => 1608115-59-8
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3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one
Catalogue No.:PA 07 24670
Molecular Formula : C22H23ClFN3O4
Molecular Weight : 447.89
stdClass Object
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[weight] => 485.77
[form] => C21H20Cl3FN4O2
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7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 24680
Molecular Formula : C21H20Cl3FN4O2
Molecular Weight : 485.77
stdClass Object
(
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[catalogue_number] => PA 07 24690
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[weight] => 192.17
[form] => C9H8N2O3
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6-Hydroxy-7-methoxy-4(1H)-quinazolinone
Catalogue No.:PA 07 24690
Molecular Formula : C9H8N2O3
Molecular Weight : 192.17
stdClass Object
(
[pname] => 4-Isopropoxy-7-methoxyquinazolin-6-yl acetate
[catalogue_number] => PA 07 24700
[category_ids] => ,80,79,78,82,70,
[chemical_name] =>
[weight] => 276.29
[form] => C14H16N2O4
[cas] => NA
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4-Isopropoxy-7-methoxyquinazolin-6-yl acetate
Catalogue No.:PA 07 24700
Molecular Formula : C14H16N2O4
Molecular Weight : 276.29
stdClass Object
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[pname] => Gefitinib-d3
[catalogue_number] => PA STI 044040
[category_ids] => ,79,80,71,78,70,82,98,
[chemical_name] =>
[weight] => 449.92
[form] => C22H21D3ClFN4O3
[cas] => 1173976-40-3
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Catalogue No.:PA STI 044040
Molecular Formula : C22H21D3ClFN4O3
Molecular Weight : 449.92
stdClass Object
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[catalogue_number] => PA 07 24730
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 309.36
[form] => C15H23N3O4
[cas] => 246512-44-7
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1-(2-amino-4’-methoxy-[1,1’-biphenyl]-4-yl)ethanone
Catalogue No.:PA 07 24730
Molecular Formula : C15H23N3O4
Molecular Weight : 309.36
stdClass Object
(
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[catalogue_number] => PA 07 24740
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[chemical_name] =>
[weight] => 310.35
[form] => C15H22N2O5
[cas] => 1640351-46-7
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2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzamide
Catalogue No.:PA 07 24740
Molecular Formula : C15H22N2O5
Molecular Weight : 310.35
stdClass Object
(
[pname] => 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
[catalogue_number] => PA 07 24710
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[chemical_name] =>
[weight] => 291.35
[form] => C15H21N3O3
[cas] => 675126-27-9
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2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
Catalogue No.:PA 07 24710
Molecular Formula : C15H21N3O3
Molecular Weight : 291.35
stdClass Object
(
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[catalogue_number] => PA 07 24720
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 321.33
[form] => C15H19N3O5
[cas] => 675126-26-8
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4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile
Catalogue No.:PA 07 24720
Molecular Formula : C15H19N3O5
Molecular Weight : 321.33
stdClass Object
(
[pname] => N'-(2-Cyano-5-methoxy-4-(3-morpholinopropoxy)phenyl)-N,N-dimethylformimidamide
[catalogue_number] => PA 07 24750
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[chemical_name] =>
[weight] => 346.43
[form] => C18H26N4O3
[cas] => 950596-57-3
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N'-(2-Cyano-5-methoxy-4-(3-morpholinopropoxy)phenyl)-N,N-dimethylformimidamide
Catalogue No.:PA 07 24750
Molecular Formula : C18H26N4O3
Molecular Weight : 346.43
stdClass Object
(
[pname] => 8-Methoxy-4-oxo-3,4-dihydroquinazolin-7-yl acetate
[catalogue_number] => PA 07 24760
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[chemical_name] =>
[weight] => 234.21
[form] => C11H10N2O4
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8-Methoxy-4-oxo-3,4-dihydroquinazolin-7-yl acetate
Catalogue No.:PA 07 24760
Molecular Formula : C11H10N2O4
Molecular Weight : 234.21
stdClass Object
(
[pname] => 7-Methoxy-4-oxo-3,4-dihydroquinazolin-8-yl Acetate
[catalogue_number] => PA 07 24770
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[chemical_name] =>
[weight] => 234.21
[form] => C11H10N2O4
[cas] => NA
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7-Methoxy-4-oxo-3,4-dihydroquinazolin-8-yl Acetate
Catalogue No.:PA 07 24770
Molecular Formula : C11H10N2O4
Molecular Weight : 234.21
stdClass Object
(
[pname] => 4-chloro-7-methoxyquinazolin-6-yl acetate
[catalogue_number] => PA 07 0241000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 252.65
[form] => C11H9ClN2O3
[cas] => 230955-75-6
[pslug] => 230955-75-6-4-chloro-7-methoxyquinazolin-6-yl-acetate-pa070241000
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4-chloro-7-methoxyquinazolin-6-yl acetate
Catalogue No.:PA 07 0241000
Molecular Formula : C11H9ClN2O3
Molecular Weight : 252.65
stdClass Object
(
[pname] => Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate
[catalogue_number] => PA 07 0241001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 324.38
[form] => C16H24N2O5
[cas] => 214472-41-0
[pslug] => 214472-41-0-methyl-2-amino-4-methoxy-5-3-morpholinopropoxy-benzoate-pa070241001
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Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate
Catalogue No.:PA 07 0241001
Molecular Formula : C16H24N2O5
Molecular Weight : 324.38
stdClass Object
(
[pname] => Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate
[catalogue_number] => PA 07 0241002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 354.36
[form] => C16H22N2O7
[cas] => 214472-37-4
[pslug] => 214472-37-4-methyl-4-methoxy-5-3-morpholinopropoxy-2-nitrobenzoate-pa070241002
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Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate
Catalogue No.:PA 07 0241002
Molecular Formula : C16H22N2O7
Molecular Weight : 354.36
stdClass Object
(
[pname] => Gefitinib Nitroso Impurity
[catalogue_number] => PA 07 0241003
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 475.91
[form] => C22H23ClFN5O4
[cas] => NA
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Gefitinib Nitroso Impurity
Catalogue No.:PA 07 0241003
Molecular Formula : C22H23ClFN5O4
Molecular Weight : 475.91
stdClass Object
(
[pname] => Gefitinib-D6
[catalogue_number] => PA STI 089397
[category_ids] => ,98,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 452.94
[form] => C22H18D6ClFN4O3
[cas] => 1228664-49-0
[pslug] => 1228664-49-0-gefitinib-d6-pasti089397
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Catalogue No.:PA STI 089397
Molecular Formula : C22H18D6ClFN4O3
Molecular Weight : 452.94
stdClass Object
(
[pname] => 4-(3-Bromopropyl)morpholine Hydrochloride
[catalogue_number] => PA 07 0241004
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 244.56
[form] => C7H15BrClNO
[cas] => 134187-43-2
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4-(3-Bromopropyl)morpholine Hydrochloride
Catalogue No.:PA 07 0241004
Molecular Formula : C7H15BrClNO
Molecular Weight : 244.56
stdClass Object
(
[pname] => 4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid
[catalogue_number] => PA 07 0241005
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 234.21
[form] => C11H10N2O4
[cas] => 179688-53-0
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4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid
Catalogue No.:PA 07 0241005
Molecular Formula : C11H10N2O4
Molecular Weight : 234.21
stdClass Object
(
[pname] => 1,3-Dimorpholinopropane
[catalogue_number] => PA 07 0241006
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 214.31
[form] => C11H22N2O2
[cas] => 48152-09-6
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Catalogue No.:PA 07 0241006
Molecular Formula : C11H22N2O2
Molecular Weight : 214.31
stdClass Object
(
[pname] => 6,7-Dimethoxyquinazolin-4(3H)-one
[catalogue_number] => PA 07 0241007
[category_ids] => ,79,80,71,78,70,82,
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[weight] => 206.2
[form] => C10H10N2O3
[cas] => 13794-72-4
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6,7-Dimethoxyquinazolin-4(3H)-one
stdClass Object
(
[pname] => Methyl 2-amino-4,5-dimethoxybenzoate
[catalogue_number] => PA 07 0241008
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 211.22
[form] => C10H13NO4
[cas] => 26759-46-6
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Methyl 2-amino-4,5-dimethoxybenzoate
Catalogue No.:PA 07 0241008
Molecular Formula : C10H13NO4
Molecular Weight : 211.22
stdClass Object
(
[pname] => 2-Chloro-1-fluoro-4-nitrobenzene
[catalogue_number] => PA 07 0241009
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 175.54
[form] => C6H3ClFNO2
[cas] => 350-30-1
[pslug] => 350-30-1-2-chloro-1-fluoro-4-nitrobenzene-pa070241009
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2-Chloro-1-fluoro-4-nitrobenzene
Catalogue No.:PA 07 0241009
Molecular Formula : C6H3ClFNO2
Molecular Weight : 175.54
stdClass Object
(
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[catalogue_number] => PA 07 0241010
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 446.91
[form] => C22H24ClFN4O3
[cas] => 909863-33-8
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N-(3-Chloro-2-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 0241010
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.91
stdClass Object
(
[pname] => N-(3-Chloro-4-fluorophenyl)-7-methoxy-5-(3-morpholinopropoxy)quinazolin-4-amine
[catalogue_number] => PA 07 0241011
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[weight] => 446.91
[form] => C22H24ClFN4O3
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N-(3-Chloro-4-fluorophenyl)-7-methoxy-5-(3-morpholinopropoxy)quinazolin-4-amine
Catalogue No.:PA 07 0241011
Molecular Formula : C22H24ClFN4O3
Molecular Weight : 446.91
