gemcitabine
Gemcitabine is a nucleoside analog used as chemotherapy. It is marketed as Gemzar® by Eli Lilly and Company. Gemcitabine is used in various carcinomas: non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. Reference standards of Gemcitabine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Gemcitabine - API Standards
Catalogue No.:PA 07 55000
Molecular Formula : C9H11F2N3O4
Molecular Weight : 263.20
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[pname] => 1'-Epi Gemcitabine Hydrochloride
[catalogue_number] => PA 07 05510
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[weight] => 299.66
[form] => C9H12ClF2N3O4
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1'-Epi Gemcitabine Hydrochloride
Catalogue No.:PA 07 05510
Molecular Formula : C9H12ClF2N3O4
Molecular Weight : 299.66
stdClass Object
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[pname] => Gemcitabine Monophosphate Formate Salt
[catalogue_number] => PA 07 05520
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[weight] => 389.2
[form] => C10H14F2N3O9P
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Gemcitabine Monophosphate Formate Salt
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[pname] => Gemcitabine Diphosphate Choline
[catalogue_number] => PA 07 05530
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[weight] => 508.31
[form] => C14H24F2N4O10P2
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Gemcitabine Diphosphate Choline
Catalogue No.:PA 07 05530
Molecular Formula : C14H24F2N4O10P2
Molecular Weight : 508.31
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[catalogue_number] => PA 07 05540
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[weight] => 705.52
[form] => C21H44F2N5O13P3
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Gemcitabine Triphosphate Ditriethylamine
Catalogue No.:PA 07 05540
Molecular Formula : C21H44F2N5O13P3
Molecular Weight : 705.52
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[weight] => 474.25
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Gemcitabine Diphosphate Ammonium Salt
Catalogue No.:PA 07 05550
Molecular Formula : C9H22F2N6O10P2
Molecular Weight : 474.25
stdClass Object
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[pname] => 5-O-Acetyl Gemcitabine
[catalogue_number] => PA 07 05570
[category_ids] => 80,82,70,78,79
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[weight] => 305.23
[form] => C11H13F2N3O5
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Catalogue No.:PA 07 05570
Molecular Formula : C11H13F2N3O5
Molecular Weight : 305.23
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Gemcitabine Diphosphate Triethylamine Salt
Catalogue No.:PA 07 05580
Molecular Formula : C27H58F2N6O10P2
Molecular Weight : 726.73
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1'-Epi Gemcitabine-13C,15N2 Hydrochloride
Catalogue No.:PA STI 037260
Molecular Formula : C813CH12ClF2N15N2O4
Molecular Weight : 302.64
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Gemcitabine-13C,15N2 Hydrochloride
Catalogue No.:PA STI 044050
Molecular Formula : C813CH12ClF2N15N2O4
Molecular Weight : 302.64
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Gemcitabine-13C3,15N2 Hydrochloride
Catalogue No.:PA STI 044060
Molecular Formula : C613C3H12ClF2N15N2O4
Molecular Weight : 304.62
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Gemcitabine Triphosphate-13C,15N2 Ditriethylamine
Catalogue No.:PA STI 044070
Molecular Formula : C2013CH44F2N315N2O13P3
Molecular Weight : 708.50
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((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate
Catalogue No.:PA 07 0051000
Molecular Formula : C19H16F2O6
Molecular Weight : 378.33
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Catalogue No.:PA 07 0551000
Molecular Formula : C9H11F2N3O4
Molecular Weight : 263.20
stdClass Object
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[weight] => 471.42
[form] => C23H19F2N3O6
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1'-Epi Gemcitabine 3',5'-Dibenzoate
Catalogue No.:PA 07 0551001
Molecular Formula : C23H19F2N3O6
Molecular Weight : 471.42
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2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanes
Catalogue No.:PA 07 0551002
Molecular Formula : C20H18F2O8S
Molecular Weight : 456.41
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N-Benzoyl-2'-deoxy-2',2'-difluorocytidine 3’-benzoate
Catalogue No.:PA 07 0051001
Molecular Formula : C23H19F2N3O6
Molecular Weight : 471.42
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((2R,3R,5R)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate
Catalogue No.:PA 07 0551003
Molecular Formula : C20H18F2O8S
Molecular Weight : 456.41
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3’-Epi Gemcitabine 3’,5’-Dibenzoate
Catalogue No.:PA 07 0551004
Molecular Formula : C24H20F2N2O6
Molecular Weight : 470.43
stdClass Object
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Catalogue No.:PA 07 0551005
Molecular Formula : C16H15F2N3O5
Molecular Weight : 367.31
stdClass Object
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(2R,3R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl benzoate
Catalogue No.:PA 07 0551006
Molecular Formula : C16H15F2N3O5
Molecular Weight : 367.31
stdClass Object
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[catalogue_number] => PA 07 0551008
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1,2:5,6-Di-O-isopropylidene-D-glucitol
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2-Deoxy-2,2-difluoro-4,5-O-isopropylidene-D-erythro-pentonic Acid Ethyl Ester
Catalogue No.:PA 07 0551007
Molecular Formula : C10H16F2O5
Molecular Weight : 254.23
stdClass Object
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[catalogue_number] => PA 07 0551009
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[weight] => 376.31
[form] => C19H14F2O6
[cas] => 122111-01-7
[pslug] => 122111-01-7-2-deoxy-2-2-difluoro-d-erythro-pentofuranos-1-ulose-3-5-dibenzoate-pa070551009
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2-Deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate
Catalogue No.:PA 07 0551009
Molecular Formula : C19H14F2O6
Molecular Weight : 376.31
stdClass Object
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[catalogue_number] => PA 07 0551010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 272.2
[form] => C12H10F2O5
[cas] => 122111-07-3
[pslug] => 122111-07-3-2r-3r-4-4-difluoro-2-hydroxymethyl-5-oxotetrahydrofuran-3-yl-benzoate-pa070551010
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(2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate
stdClass Object
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[pname] => (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
[catalogue_number] => PA 07 0551011
[category_ids] => ,76,78,70,82,
[chemical_name] =>
[weight] => 168.1
[form] => C5H6F2O4
[cas] => 95058-77-8
[pslug] => 95058-77-8-4r-5r-3-3-difluoro-4-hydroxy-5-hydroxymethyl-dihydrofuran-2-3h-one-pa070551011
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(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
stdClass Object
(
[pname] => 2',5-Difluoro-2'-deoxy-1-arabinosyluracil
[catalogue_number] => PA 07 0551012
[category_ids] => ,80,79,78,82,70,
[chemical_name] =>
[weight] => 264.18
[form] => C9H10F2N2O5
[cas] => 69123-95-1
[pslug] => 69123-95-1-2-5-difluoro-2-deoxy-1-arabinosyluracil-pa070551012
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2',5-Difluoro-2'-deoxy-1-arabinosyluracil
Catalogue No.:PA 07 0551012
Molecular Formula : C9H10F2N2O5
Molecular Weight : 264.18
stdClass Object
(
[pname] => (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol
[catalogue_number] => PA 07 0551013
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[weight] => 170.11
[form] => C5H8F2O4
[cas] => 861445-88-7
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(4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol
Catalogue No.:PA 07 0551013
Molecular Formula : C5H8F2O4
Molecular Weight : 170.11