Leflunomide-impurities | Pharmaffiliates

leflunomide

An immunomodulatory drug, Leflunomide is used to treat rheumatoid arthritis and psoriatic arthritis. An inhibitor of enzyme dihydroorotate dehydrogenase which plays a key role in the synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA. Reference standards of Leflunomide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Leflunomide - Impurity B
    [catalogue_number] => PA 12 08020
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    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 163451-81-8
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PA 12 08020

Leflunomide - Impurity B


  • Catalogue No.:PA 12 08020

  • CAS :

    163451-81-8

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

20% OFF
stdClass Object
(
    [pname] => Leflunomide - Impurity C
    [catalogue_number] => PA 12 08030
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 61643-23-0
    [pslug] => 61643-23-0-leflunomide-impurity-c-pa1208030
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PA 12 08030

Leflunomide - Impurity C


  • Catalogue No.:PA 12 08030

  • CAS :

    61643-23-0

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

20% OFF
stdClass Object
(
    [pname] => Leflunomide - Impurity A (Hydrochloride)
    [catalogue_number] => PA 12 0080011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 197.59
    [form] => C7H7ClF3N
    [cas] => 90774-69-9
    [pslug] => 90774-69-9-leflunomide-impurity-a-hydrochloride-pa120080011
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PA 12 0080011

Leflunomide - Impurity A (Hydrochloride)


  • Catalogue No.:PA 12 0080011

  • CAS :

    90774-69-9

  • Molecular Formula : C7H7ClF3N

  • Molecular Weight : 197.59

stdClass Object
(
    [pname] => Leflunomide - Impurity D
    [catalogue_number] => PA 12 08040
    [category_ids] => ,71,70,78,82,
    [chemical_name] => 
    [weight] => 127.10
    [form] => C5H5NO3
    [cas] => 42831-50-5
    [pslug] => 42831-50-5-leflunomide-impurity-d-pa1208040
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PA 12 08040

Leflunomide - Impurity D


  • Catalogue No.:PA 12 08040

  • CAS :

    42831-50-5

  • Molecular Formula : C5H5NO3

  • Molecular Weight : 127.10

stdClass Object
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    [pname] => Leflunomide - Impurity E
    [catalogue_number] => PA 12 08050
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 208401-20-1
    [pslug] => 208401-20-1-leflunomide-impurity-e-pa1208050
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PA 12 08050

Leflunomide - Impurity E


  • Catalogue No.:PA 12 08050

  • CAS :

    208401-20-1

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

stdClass Object
(
    [pname] => Leflunomide - Impurity F
    [catalogue_number] => PA 12 08060
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 1403564-06-6
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PA 12 08060

Leflunomide - Impurity F


  • Catalogue No.:PA 12 08060

  • CAS :

    1403564-06-6

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

stdClass Object
(
    [pname] => Leflunomide - Impurity G
    [catalogue_number] => PA 12 08070
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 216.24
    [form] => C12 H12 N2 O2
    [cas] => 724429-16-7
    [pslug] => 724429-16-7-leflunomide-impurity-g-pa1208070
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PA 12 08070

Leflunomide - Impurity G


  • Catalogue No.:PA 12 08070

  • CAS :

    724429-16-7

  • Molecular Formula : C12 H12 N2 O2

  • Molecular Weight : 216.24

stdClass Object
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    [pname] => 3-Methylisoxazole-4-carboxylic Acid
    [catalogue_number] => PA 12 08510
    [category_ids] => ,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 127.1
    [form] => C5H5NO3
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PA 12 08510

3-Methylisoxazole-4-carboxylic Acid


  • Catalogue No.:PA 12 08510

  • CAS :

    17153-20-7

  • Molecular Formula : C5H5NO3

  • Molecular Weight : 127.1

stdClass Object
(
    [pname] => 5-Methylisoxazole-3-carboxylic-d4 Acid
    [catalogue_number] => PA STI 062330
    [category_ids] => ,71,75,98,78,70,82,
    [chemical_name] => 
    [weight] => 131.12
    [form] => C5HD4NO3
    [cas] => 1267623-84-6
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PA STI 062330

5-Methylisoxazole-3-carboxylic-d4 Acid


  • Catalogue No.:PA STI 062330

  • CAS :

    1267623-84-6

  • Molecular Formula : C5HD4NO3

  • Molecular Weight : 131.12

stdClass Object
(
    [pname] => 5-Hydroxy Leflunomide-d4 (Metabolite M2)
    [catalogue_number] => PA STI 049540
    [category_ids] => ,80,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 290.23
    [form] => C12H5D4F3N2O3
    [cas] => 1794789-76-6
    [pslug] => 1794789-76-6-5-hydroxy-leflunomide-d4-metabolite-m2-pasti049540
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PA STI 049540

5-Hydroxy Leflunomide-d4 (Metabolite M2)


  • Catalogue No.:PA STI 049540

  • CAS :

    1794789-76-6

  • Molecular Formula : C12H5D4F3N2O3

  • Molecular Weight : 290.23

stdClass Object
(
    [pname] => Leflunomide-d4
    [catalogue_number] => PA STI 056310
    [category_ids] => ,80,71,98,78,70,82,81,
    [chemical_name] => 
    [weight] => 274.23
    [form] => C12H5D4F3N2O2
    [cas] => 1189987-23-2
    [pslug] => 1189987-23-2-leflunomide-d4-pasti056310
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PA STI 056310

Leflunomide-d4


  • Catalogue No.:PA STI 056310

  • CAS :

    1189987-23-2

  • Molecular Formula : C12H5D4F3N2O2

  • Molecular Weight : 274.23

stdClass Object
(
    [pname] => Lenalidomide-d5
    [catalogue_number] => PA STI 056311
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 264.29
    [form] => C13H8D5N3O3
    [cas] => NA
    [pslug] => lenalidomide-d5-pasti056311
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PA STI 056311

Lenalidomide-d5


  • Catalogue No.:PA STI 056311

  • CAS :

    NA

  • Molecular Formula : C13H8D5N3O3

  • Molecular Weight : 264.29

stdClass Object
(
    [pname] => rac Lenalidomide-13C5
    [catalogue_number] => PA STI 056320
    [category_ids] => ,98,78,70,82,
    [chemical_name] => 
    [weight] => 264.22
    [form] => C813C5H13N3O3
    [cas] => 1219332-91-8
    [pslug] => 1219332-91-8-rac-lenalidomide-13c5-pasti056320
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PA STI 056320

rac Lenalidomide-13C5


  • Catalogue No.:PA STI 056320

  • CAS :

    1219332-91-8

  • Molecular Formula : C813C5H13N3O3

  • Molecular Weight : 264.22

stdClass Object
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    [pname] => 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
    [catalogue_number] => PA 12 08530
    [category_ids] => 117,76,82,78,75,70
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 108605-62-5
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PA 12 08530

2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide


  • Catalogue No.:PA 12 08530

  • CAS :

    108605-62-5

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

stdClass Object
(
    [pname] => 3-Methylisoxazole-4-carboxylic Acid Ethyl Ester
    [catalogue_number] => PA 12 08540
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 155.15
    [form] => C7H9NO3
    [cas] => 20328-15-8
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PA 12 08540

3-Methylisoxazole-4-carboxylic Acid Ethyl Ester


  • Catalogue No.:PA 12 08540

  • CAS :

    20328-15-8

  • Molecular Formula : C7H9NO3

  • Molecular Weight : 155.15

stdClass Object
(
    [pname] => Ethyl 5-Methylisoxazole-4-carboxylate
    [catalogue_number] => PA 12 08550
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 155.15
    [form] => C7H9NO3
    [cas] => 51135-73-0
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PA 12 08550

Ethyl 5-Methylisoxazole-4-carboxylate


  • Catalogue No.:PA 12 08550

  • CAS :

    51135-73-0

  • Molecular Formula : C7H9NO3

  • Molecular Weight : 155.15

stdClass Object
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    [pname] => 5-Hydroxy leflunomide
    [catalogue_number] => PA 12 0081000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 286.21
    [form] => C12H9F3N2O3
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PA 12 0081000

5-Hydroxy leflunomide


  • Catalogue No.:PA 12 0081000

  • CAS :

    1058722-46-5

  • Molecular Formula : C12H9F3N2O3

  • Molecular Weight : 286.21

stdClass Object
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    [pname] =>  2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide
    [catalogue_number] => PA 12 0081001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 228.17
    [form] => C10H7F3N2O
    [cas] => 419534-37-5
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PA 12 0081001

 2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide


  • Catalogue No.:PA 12 0081001

  • CAS :

    419534-37-5

  • Molecular Formula : C10H7F3N2O

  • Molecular Weight : 228.17