Lifitegrast-impurities | Pharmaffiliates

lifitegrast

lifitegrast is used to treat the signs and symptoms of dry eye disease. It is an FDA approved drug indicated. Lifitegrast reduces inflammation by inhibiting inflammatory cell binding. Reference standards of Lifitegrast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Lifitegrast - API Standards 
    [catalogue_number] => PA 39 04000
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 615.48
    [form] => C29H24Cl2N2O7S
    [cas] => 1025967-78-5
    [pslug] => 1025967-78-5-lifitegrast-api-pa3904000
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PA 39 04000

Lifitegrast - API Standards


  • Catalogue No.:PA 39 04000

  • CAS :

    1025967-78-5

  • Molecular Formula : C29H24Cl2N2O7S

  • Molecular Weight : 615.48

stdClass Object
(
    [pname] => (S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid Hydrochloride
    [catalogue_number] => PA 39 04510
    [category_ids] => 78,82,70
    [chemical_name] => 
    [weight] => 507.81
    [form] => C20H21Cl3N2O5S
    [cas] => 2271054-95-4
    [pslug] => 2271054-95-4-s-2-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoic-acid-hydrochloride-pa3904510
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PA 39 04510

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid Hydrochloride


  • Catalogue No.:PA 39 04510

  • CAS :

    2271054-95-4

  • Molecular Formula : C20H21Cl3N2O5S

  • Molecular Weight : 507.81

stdClass Object
(
    [pname] => (S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 04520
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 513.39
    [form] => C22H22Cl2N2O6S
    [cas] => NA
    [pslug] => s-2-2-acetyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoic-acid-pa3904520
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PA 39 04520

(S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 04520

  • CAS :

    NA

  • Molecular Formula : C22H22Cl2N2O6S

  • Molecular Weight : 513.39

stdClass Object
(
    [pname] => Benzofuran-6-carboxylic Acid
    [catalogue_number] => PA 39 04530
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 162.14
    [form] => C9H6O3
    [cas] => 77095-51-3
    [pslug] => 77095-51-3-benzofuran-6-carboxylic-acid-pa3904530
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PA 39 04530

Benzofuran-6-carboxylic Acid


  • Catalogue No.:PA 39 04530

  • CAS :

    77095-51-3

  • Molecular Formula : C9H6O3

  • Molecular Weight : 162.14

stdClass Object
(
    [pname] => (S)-2-(2-(Benzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 04540
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 546.59
    [form] => C29H26N2O7S
    [cas] => 2295862-00-7
    [pslug] => 2295862-00-7-s-2-2-benzofuran-6-carbonyl-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoic-acid-pa3904540
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PA 39 04540

(S)-2-(2-(Benzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 04540

  • CAS :

    2295862-00-7

  • Molecular Formula : C29H26N2O7S

  • Molecular Weight : 546.59

stdClass Object
(
    [pname] => Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
    [catalogue_number] => PA 39 04560
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 705.6
    [form] => C36H30Cl2N2O7S
    [cas] => 1194550-67-8
    [pslug] => 1194550-67-8-benzyl-s-2-2-benzofuran-6-carbonyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoate-pa3904560
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PA 39 04560

Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate


  • Catalogue No.:PA 39 04560

  • CAS :

    1194550-67-8

  • Molecular Formula : C36H30Cl2N2O7S

  • Molecular Weight : 705.6

stdClass Object
(
    [pname] => Methyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
    [catalogue_number] => PA 39 04570
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 629.51
    [form] => C30H26Cl2N2O7S
    [cas] => 2295862-29-0
    [pslug] => 2295862-29-0-methyl-s-2-2-benzofuran-6-carbonyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoate-pa3904570
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PA 39 04570

Methyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate


  • Catalogue No.:PA 39 04570

  • CAS :

    2295862-29-0

  • Molecular Formula : C30H26Cl2N2O7S

  • Molecular Weight : 629.51

stdClass Object
(
    [pname] => Lifitegrast R-Isomer
    [catalogue_number] => PA 39 0041000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 615.48
    [form] => C29H24Cl2N2O7S
    [cas] => 2271299-08-0
    [pslug] => 2271299-08-0-lifitegrast-r-isomer-pa390041000
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PA 39 0041000

Lifitegrast R-Isomer


  • Catalogue No.:PA 39 0041000

  • CAS :

    2271299-08-0

  • Molecular Formula : C29H24Cl2N2O7S

  • Molecular Weight : 615.48

stdClass Object
(
    [pname] => (S)-2-(2-(Benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid
    [catalogue_number] => PA 39 0041001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 581.04
    [form] => C29H25ClN2O7S
    [cas] => NA
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PA 39 0041001

(S)-2-(2-(Benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid


  • Catalogue No.:PA 39 0041001

  • CAS :

    NA

  • Molecular Formula : C29H25ClN2O7S

  • Molecular Weight : 581.04

stdClass Object
(
    [pname] => (S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid
    [catalogue_number] => PA 39 0041002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 581.04
    [form] => C29H25ClN2O7S
    [cas] => NA
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PA 39 0041002

(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid


  • Catalogue No.:PA 39 0041002

  • CAS :

    NA

  • Molecular Formula : C29H25ClN2O7S

  • Molecular Weight : 581.04

stdClass Object
(
    [pname] => 5-Bromo-2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
    [catalogue_number] => PA 39 0041003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 390.66
    [form] => C15H17BrClNO4
    [cas] => NA
    [pslug] => 5-bromo-2-tert-butoxycarbonyl-7-chloro-1-2-3-4-tetrahydroisoquinoline-6-carboxylic-acid-pa390041003
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PA 39 0041003

5-Bromo-2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid


  • Catalogue No.:PA 39 0041003

  • CAS :

    NA

  • Molecular Formula : C15H17BrClNO4

  • Molecular Weight : 390.66

stdClass Object
(
    [pname] => 7-Bromo-2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
    [catalogue_number] => PA 39 0041004
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    [chemical_name] => 
    [weight] => 390.66
    [form] => C15H17BrClNO4
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PA 39 0041004

7-Bromo-2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid


  • Catalogue No.:PA 39 0041004

  • CAS :

    NA

  • Molecular Formula : C15H17BrClNO4

  • Molecular Weight : 390.66

stdClass Object
(
    [pname] => (S)-2-(2-(Benzofuran-6-carbonyl)-5-bromo-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid
    [catalogue_number] => PA 39 0041005
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    [chemical_name] => 
    [weight] => 655.99
    [form] => C31H28BrClN2O5S
    [cas] => NA
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PA 39 0041005

(S)-2-(2-(Benzofuran-6-carbonyl)-5-bromo-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid


  • Catalogue No.:PA 39 0041005

  • CAS :

    NA

  • Molecular Formula : C31H28BrClN2O5S

  • Molecular Weight : 655.99

stdClass Object
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    [pname] => (S)-2-(2-(Benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid
    [catalogue_number] => PA 39 0041006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 655.99
    [form] => C31H28BrClN2O5S
    [cas] => NA
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PA 39 0041006

(S)-2-(2-(Benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid


  • Catalogue No.:PA 39 0041006

  • CAS :

    NA

  • Molecular Formula : C31H28BrClN2O5S

  • Molecular Weight : 655.99

stdClass Object
(
    [pname] => (S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2-dihydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid
    [catalogue_number] => PA 39 0041007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 613.46
    [form] => C29H22Cl2N2O7S
    [cas] => NA
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PA 39 0041007

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2-dihydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid


  • Catalogue No.:PA 39 0041007

  • CAS :

    NA

  • Molecular Formula : C29H22Cl2N2O7S

  • Molecular Weight : 613.46

stdClass Object
(
    [pname] => (S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid
    [catalogue_number] => PA 39 0041008
    [category_ids] => ,75,76,78,70,82,
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    [weight] => 629.46
    [form] => C29H22Cl2N2O8S
    [cas] => NA
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PA 39 0041008

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid


  • Catalogue No.:PA 39 0041008

  • CAS :

    NA

  • Molecular Formula : C29H22Cl2N2O8S

  • Molecular Weight : 629.46

stdClass Object
(
    [pname] => (S)-2-(2-(Benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid
    [catalogue_number] => PA 39 0041009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 616.29
    [form] => C28H21BrCl2N2O5
    [cas] => NA
    [pslug] => s-2-2-benzofuran-6-carbonyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-bromophenyl-propanoic-acid-pa390041009
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PA 39 0041009

(S)-2-(2-(Benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid


  • Catalogue No.:PA 39 0041009

  • CAS :

    NA

  • Molecular Formula : C28H21BrCl2N2O5

  • Molecular Weight : 616.29

stdClass Object
(
    [pname] => (S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3(methylsulfonyl)phenyl)propanoicacid
    [catalogue_number] => PA 39 0041010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 840.74
    [form] => C39H35Cl2N3O10S2
    [cas] => NA
    [pslug] => s-2-s-2-2-benzofuran-6-carbonyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanamido-3-3-methylsulfonyl-phenyl-propanoicacid-pa390041010
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PA 39 0041010

(S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3(methylsulfonyl)phenyl)propanoicacid


  • Catalogue No.:PA 39 0041010

  • CAS :

    NA

  • Molecular Formula : C39H35Cl2N3O10S2

  • Molecular Weight : 840.74

stdClass Object
(
    [pname] => 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
    [catalogue_number] => PA 39 0041011
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 282.55
    [form] => C10H10Cl3NO2
    [cas] => 1289646-93-0
    [pslug] => 1289646-93-0-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxylic-acid-hydrochloride-pa390041011
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PA 39 0041011

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride


  • Catalogue No.:PA 39 0041011

  • CAS :

    1289646-93-0

  • Molecular Formula : C10H10Cl3NO2

  • Molecular Weight : 282.55

stdClass Object
(
    [pname] => 2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid
    [catalogue_number] => PA 39 0041012
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 390.22
    [form] => C19H13Cl2NO4
    [cas] => 2129597-34-6
    [pslug] => 2129597-34-6-2-benzofuran-6-carbonyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxylic-acid-pa390041012
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PA 39 0041012

2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid


  • Catalogue No.:PA 39 0041012

  • CAS :

    2129597-34-6

  • Molecular Formula : C19H13Cl2NO4

  • Molecular Weight : 390.22

stdClass Object
(
    [pname] => tert-Butyl (S)-6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 39 0041013
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 661.59
    [form] => C32H34Cl2N2O7S
    [cas] => 1194550-61-2
    [pslug] => 1194550-61-2-tert-butyl-s-6-1-benzyloxy-3-3-methylsulfonyl-phenyl-1-oxopropan-2-yl-carbamoyl-5-7-dichloro-3-4-dihydroisoquinoline-2-1h-carboxylate-pa390041013
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PA 39 0041013

tert-Butyl (S)-6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 39 0041013

  • CAS :

    1194550-61-2

  • Molecular Formula : C32H34Cl2N2O7S

  • Molecular Weight : 661.59

stdClass Object
(
    [pname] => Benzyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
    [catalogue_number] => PA 39 0041014
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 561.47
    [form] => C27H26Cl2N2O5S
    [cas] => 1194864-18-0
    [pslug] => 1194864-18-0-benzyl-s-2-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoate-pa390041014
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PA 39 0041014

Benzyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate


  • Catalogue No.:PA 39 0041014

  • CAS :

    1194864-18-0

  • Molecular Formula : C27H26Cl2N2O5S

  • Molecular Weight : 561.47

stdClass Object
(
    [pname] => (S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 0041015
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 243.28
    [form] => C10H13NO4S
    [cas] => 1270093-99-6
    [pslug] => 1270093-99-6-s-2-amino-3-3-methylsulfonyl-phenyl-propanoic-acid-pa390041015
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PA 39 0041015

(S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 0041015

  • CAS :

    1270093-99-6

  • Molecular Formula : C10H13NO4S

  • Molecular Weight : 243.28