ponatinib

Fine Chemicals - A multi-targeted tyrosine-kinase inhibitor, Ponatinib is used in treating chronic myeloid leukemia. Shows antiangiogenic and antineoplastic activities.Reference standards of Ponatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ponatinib
    [catalogue_number] => PA 16 91000
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 532.56
    [form] => C29H27F3N6O
    [cas] => 943319-70-8
    [pslug] => 943319-70-8-ponatinib-api-pa1691000
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PA 16 91000
PA 16 91000

Ponatinib

  • Catalogue No.:PA 16 91000

  • CAS :

    943319-70-8

  • Molecular Formula : C29H27F3N6O

  • Molecular Weight : 532.56

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stdClass Object
(
    [pname] => 3-Ethynylimidazo[1,2-b]pyridazine
    [catalogue_number] => PA 16 91510
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 143.15
    [form] => C8H5N3
    [cas] => 943320-61-4
    [pslug] => 943320-61-4-3-ethynylimidazo-1-2-b-pyridazine-pa1691510
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PA 16 91510
PA 16 91510

3-Ethynylimidazo[1,2-b]pyridazine

  • Catalogue No.:PA 16 91510

  • CAS :

    943320-61-4

  • Molecular Formula : C8H5N3

  • Molecular Weight : 143.15

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stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide
    [catalogue_number] => PA 16 91520
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 433.16
    [form] => C16H11F3INO2
    [cas] => 1638193-91-5
    [pslug] => 1638193-91-5-n-4-formyl-3-trifluoromethyl-phenyl-3-iodo-4-methylbenzamide-pa1691520
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PA 16 91520
PA 16 91520

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide

  • Catalogue No.:PA 16 91520

  • CAS :

    1638193-91-5

  • Molecular Formula : C16H11F3INO2

  • Molecular Weight : 433.16

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stdClass Object
(
    [pname] => N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide
    [catalogue_number] => PA 16 91530
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 448.4
    [form] => C24H15F3N4O2
    [cas] => 1638193-92-6
    [pslug] => 1638193-92-6-n-4-formyl-3-trifluoromethyl-phenyl-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzamide-pa1691530
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PA 16 91530
PA 16 91530

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide

  • Catalogue No.:PA 16 91530

  • CAS :

    1638193-92-6

  • Molecular Formula : C24H15F3N4O2

  • Molecular Weight : 448.4

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stdClass Object
(
    [pname] => 3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 91540
    [category_ids] => ,71,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 415.45
    [form] => C23H24F3N3O
    [cas] => 957147-18-1
    [pslug] => 957147-18-1-3-ethynyl-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa1691540
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PA 16 91540
PA 16 91540

3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 16 91540

  • CAS :

    957147-18-1

  • Molecular Formula : C23H24F3N3O

  • Molecular Weight : 415.45

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Details 
stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 91560
    [category_ids] => ,82,78,70,
    [chemical_name] => 
    [weight] => 518.53
    [form] => C28H25F3N6O
    [cas] => 943319-87-7
    [pslug] => 943319-87-7-3-imidazo[1-2-b]pyridazin-3-ylethynyl-4-methyl-n-4-piperazin-1-ylmethyl-3-trifluoromethyl-phenyl-benzamide-pa1691560
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PA 16 91560
PA 16 91560

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 16 91560

  • CAS :

    943319-87-7

  • Molecular Formula : C28H25F3N6O

  • Molecular Weight : 518.53

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stdClass Object
(
    [pname] => Ponatinib N-Oxide
    [catalogue_number] => PA 16 0911000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 548.57
    [form] => C29H27F3N6O2
    [cas] => 2227480-51-3
    [pslug] => 2227480-51-3-ponatinib-n-oxide-pa160911000
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PA 16 0911000
PA 16 0911000

Ponatinib N-Oxide

  • Catalogue No.:PA 16 0911000

  • CAS :

    2227480-51-3

  • Molecular Formula : C29H27F3N6O2

  • Molecular Weight : 548.57

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Details 
stdClass Object
(
    [pname] => 3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);
    [catalogue_number] => PA 16 0911001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 828.9
    [form] => C46H46F6N6O2
    [cas] => 2097674-16-1
    [pslug] => 2097674-16-1-3-3-buta-1-3-diyne-1-4-diyl-bis-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911001
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PA 16 0911001
PA 16 0911001

3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);

  • Catalogue No.:PA 16 0911001

  • CAS :

    2097674-16-1

  • Molecular Formula : C46H46F6N6O2

  • Molecular Weight : 828.9

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Details 
stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
    [catalogue_number] => PA 16 0911002
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 277.28
    [form] => C16H11N3O2
    [cas] => 1300690-48-5
    [pslug] => 1300690-48-5-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzoic-acid-pa160911002
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PA 16 0911002
PA 16 0911002

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid

  • Catalogue No.:PA 16 0911002

  • CAS :

    1300690-48-5

  • Molecular Formula : C16H11N3O2

  • Molecular Weight : 277.28

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Details 
stdClass Object
(
    [pname] => Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate
    [catalogue_number] => PA 16 0911003
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 291.31
    [form] => C17H13N3O2
    [cas] => 1356385-96-0
    [pslug] => 1356385-96-0-methyl-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzoate-pa160911003
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PA 16 0911003
PA 16 0911003

Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate

  • Catalogue No.:PA 16 0911003

  • CAS :

    1356385-96-0

  • Molecular Formula : C17H13N3O2

  • Molecular Weight : 291.31

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Details 
stdClass Object
(
    [pname] => 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911004
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 273.3
    [form] => C13H18F3N3
    [cas] => 694499-26-8
    [pslug] => 694499-26-8-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-aniline-pa160911004
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PA 16 0911004
PA 16 0911004

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

  • Catalogue No.:PA 16 0911004

  • CAS :

    694499-26-8

  • Molecular Formula : C13H18F3N3

  • Molecular Weight : 273.3

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Details 
stdClass Object
(
    [pname] => 3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 0911005
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 673.7
    [form] => C37H30F3N9O
    [cas] => NA
    [pslug] => 3-5-bis-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911005
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PA 16 0911005
PA 16 0911005

3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 16 0911005

  • CAS :

    NA

  • Molecular Formula : C37H30F3N9O

  • Molecular Weight : 673.7

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Details 
stdClass Object
(
    [pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 16 0911006
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 547.54
    [form] => C28H24F3N7O2
    [cas] => NA
    [pslug] => 3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methyl-n-4-4-nitrosopiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-benzamide-pa160911006
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PA 16 0911006
PA 16 0911006

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

  • Catalogue No.:PA 16 0911006

  • CAS :

    NA

  • Molecular Formula : C28H24F3N7O2

  • Molecular Weight : 547.54

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Details 
stdClass Object
(
    [pname] => 4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
    [catalogue_number] => PA 16 0911007
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 288.27
    [form] => C12H15F3N4O
    [cas] => NA
    [pslug] => 4-4-nitrosopiperazin-1-yl-methyl-3-trifluoromethyl-aniline-pa160911007
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PA 16 0911007
PA 16 0911007

4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

  • Catalogue No.:PA 16 0911007

  • CAS :

    NA

  • Molecular Formula : C12H15F3N4O

  • Molecular Weight : 288.27

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stdClass Object
(
    [pname] => Ponatinib N-beta-D-Glucuronide
    [catalogue_number] => PA 16 0911008
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 789.61
    [form] => C35H36BrF3N6O7
    [cas] => NA
    [pslug] => ponatinib-n-beta-d-glucuronide-pa160911008
    [latest_product] => 0
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PA 16 0911008
PA 16 0911008

Ponatinib N-beta-D-Glucuronide

  • Catalogue No.:PA 16 0911008

  • CAS :

    NA

  • Molecular Formula : C35H36BrF3N6O7

  • Molecular Weight : 789.61

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