Trabectedin-impurities | Pharmaffiliates

trabectedin

Trabectedin is used to treat cancer that has spread to other parts of the body or cannot be treated with surgery. It is an antitumor chemotherapy drug sold by Pharma Mar S.A. and Johnson and Johnson under the brand name Yondelis.Reference standards of Trabectedin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Safracin B
    [catalogue_number] => PA 47 22510
    [category_ids] => ,79,71,78,70,82,80,
    [chemical_name] => 
    [weight] => 540.61
    [form] => C28H36N4O7
    [cas] => 87578-99-2
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PA 47 22510

Safracin B


  • Catalogue No.:PA 47 22510

  • CAS :

    87578-99-2

  • Molecular Formula : C28H36N4O7

  • Molecular Weight : 540.61

stdClass Object
(
    [pname] => (R)-1-((((6R,6aR,7R,13S,14S,16R)-5-Acetoxy-8,14-dihydroxy-16-(hydroxymethyl)-9-methoxy-4,10,17-trimethyl-6,6a,7,13,14,16-hexahydro-12H-7,13-epiminobenzo[4,5]azocino[1,2-b][1,3]dioxolo[4,5-h]isoquinolin-6-yl)thio)methyl)-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid
    [catalogue_number] => PA 47 0221000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 779.86
    [form] => C39H45N3O12S
    [cas] => NA
    [pslug] => r-1-6r-6ar-7r-13s-14s-16r-5-acetoxy-8-14-dihydroxy-16-hydroxymethyl-9-methoxy-4-10-17-trimethyl-6-6a-7-13-14-16-hexahydro-12h-7-13-epiminobenzo-4-5-azocino-1-2-b-1-3-dioxolo-4-5-h-isoquinolin-6-yl-thio-methyl-6-hydroxy-7-methoxy-1-2-3-4-tetrahydroisoquinoline-1-carboxylic-acid-pa470221000
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PA 47 0221000

(R)-1-((((6R,6aR,7R,13S,14S,16R)-5-Acetoxy-8,14-dihydroxy-16-(hydroxymethyl)-9-methoxy-4,10,17-trimethyl-6,6a,7,13,14,16-hexahydro-12H-7,13-epiminobenzo[4,5]azocino[1,2-b][1,3]dioxolo[4,5-h]isoquinolin-6-yl)thio)methyl)-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid


  • Catalogue No.:PA 47 0221000

  • CAS :

    NA

  • Molecular Formula : C39H45N3O12S

  • Molecular Weight : 779.86

stdClass Object
(
    [pname] => ET-745
    [catalogue_number] => PA 47 0221001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 745.84
    [form] => C39H43N3O10S
    [cas] => 114899-28-4
    [pslug] => 114899-28-4-et-745-pa470221001
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PA 47 0221001

ET-745


  • Catalogue No.:PA 47 0221001

  • CAS :

    114899-28-4

  • Molecular Formula : C39H43N3O10S

  • Molecular Weight : 745.84

stdClass Object
(
    [pname] => ET-701
    [catalogue_number] => PA 47 0221002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 719.81
    [form] => C37H41N3O10S
    [cas] => 493024-42-3
    [pslug] => 493024-42-3-et-701-pa470221002
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PA 47 0221002

ET-701


  • Catalogue No.:PA 47 0221002

  • CAS :

    493024-42-3

  • Molecular Formula : C37H41N3O10S

  • Molecular Weight : 719.81

stdClass Object
(
    [pname] => Ecteinascidin 770
    [catalogue_number] => PA 47 0221003
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 770.85
    [form] => C40H42N4O10S
    [cas] => 114899-80-8
    [pslug] => 114899-80-8-ecteinascidin-770-pa470221003
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PA 47 0221003

Ecteinascidin 770


  • Catalogue No.:PA 47 0221003

  • CAS :

    114899-80-8

  • Molecular Formula : C40H42N4O10S

  • Molecular Weight : 770.85

stdClass Object
(
    [pname] => (7R,11S)-5-Hydroxy-4-methyl-6,7,10,11-tetrahydro-8H-7,11-epimino[1,3]dioxolo[4',5':5,6]benzo[1,2-d]oxocin-8-one
    [catalogue_number] => PA 47 0221004
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 263.25
    [form] => C13H13NO5
    [cas] => NA
    [pslug] => 7r-11s-5-hydroxy-4-methyl-6-7-10-11-tetrahydro-8h-7-11-epimino-1-3-dioxolo-4-5:5-6-benzo-1-2-d-oxocin-8-one-pa470221004
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PA 47 0221004

(7R,11S)-5-Hydroxy-4-methyl-6,7,10,11-tetrahydro-8H-7,11-epimino[1,3]dioxolo[4',5':5,6]benzo[1,2-d]oxocin-8-one


  • Catalogue No.:PA 47 0221004

  • CAS :

    NA

  • Molecular Formula : C13H13NO5

  • Molecular Weight : 263.25

stdClass Object
(
    [pname] => (R)-2-(((Allyloxy)carbonyl)amino)-3-(3,5-bis((tert-butyldimethylsilyl)oxy)-4-methoxyphenyl)propanoic Acid
    [catalogue_number] => PA 47 0221005
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 539.82
    [form] => C26H45NO7Si2
    [cas] => NA
    [pslug] => r-2-allyloxy-carbonyl-amino-3-3-5-bis-tert-butyldimethylsilyl-oxy-4-methoxyphenyl-propanoic-acid-pa470221005
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PA 47 0221005

(R)-2-(((Allyloxy)carbonyl)amino)-3-(3,5-bis((tert-butyldimethylsilyl)oxy)-4-methoxyphenyl)propanoic Acid


  • Catalogue No.:PA 47 0221005

  • CAS :

    NA

  • Molecular Formula : C26H45NO7Si2

  • Molecular Weight : 539.82

stdClass Object
(
    [pname] => Trabectedin Impurity 12
    [catalogue_number] => PA 47 0221006
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 761.84
    [form] => C39H43N3O11S
    [cas] => NA
    [pslug] => trabectedin-impurity-12-pa470221006
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PA 47 0221006

Trabectedin Impurity 12


  • Catalogue No.:PA 47 0221006

  • CAS :

    NA

  • Molecular Formula : C39H43N3O11S

  • Molecular Weight : 761.84