Catalogue number: | PA STI 080540 |
Chemical name: | Sulindac Sulfide-d6 (Major) |
CAS Number: |
NA |
Category: | stable isotopes,metabolites,impurities,pharmaceutical standards,intermediates,fine chemicals,sulphur and selenium compounds |
Synonyms: | (Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic Acid-d6; |
Molecular form: | C20H11D6FO2S |
Appearance: | NA |
Mol. Weight: | 346.45 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Labelled analogue of Sulindac Sulfide, an active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP. |
BTM: | NA |
Sulindac Sulfide-d6 (Major)
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