Catalogue number: | PA STI 080800 |
Chemical name: | TAK-960-d3 |
CAS Number: |
NA |
Category: | miscellaneous compounds,stable isotopes |
Synonyms: | 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide-d3; |
Molecular form: | CH31D3F3N7O3 |
Appearance: | NA |
Mol. Weight: | 564.62 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Isotope labelled TAK-960 is a potent and selective inhibitor of polo-like kinase 1 (PLK1), a serine/threonine protein kinase involved in key processes during mitosis. TAK-960 has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 treatments has shown significant efficacy against multiple tumor xenografts and is a potential chemotherapeutic agent for patients with advanced tumors. |
BTM: | NA |
TAK-960-d3
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