| Catalogue number: | PA PEP 000838 |
| Chemical name: | Voclosporin-d4 |
CAS Number: |
NA |
| Category: | peptides |
| Synonyms: | 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A-d4; ISATX 247-d4; R 1524-d4; trans-ISA 247-d4; |
| Molecular form: | C63H107D4N11O12 |
| Appearance: | NA |
| Mol. Weight: | 1218.65 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Labelled Voclosporin. A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile, a strong correlation between pharmacokinetic and pharmacodynamic response, and a wide therapeutic window. Immunosuppressant. |
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