MC-Val-Cit-PAB-Exatecan

In House Impurity

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Catalogue number:	PA 05 1991005
Chemical name:	MC-Val-Cit-PAB-Exatecan
CAS Number:	2504068-28-2
Category:	miscellaneous compounds,amino acid derivatives,Antibody Drug Conjugate
Synonyms:	4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl ((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)carbamate;
Molecular form:	C₅₃H₆₀FN₉O₁₂
Appearance:	Solid
Mol. Weight:	1034.11
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker