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Catalogue number: PA 04 2780000
Chemical name: Debrisoquine

CAS Number:

1131-64-2

Category: impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:

2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro; 3,4-Dihydro-2(1H)-isoquinolinecarboximidamide; 1,2,3,4-Tetrahydroisoquinoline-2-carboximidamide; 2-Amidino-1,2,3,4-tetrahydroisoquinoline; 3,4-Dihydroisoquinoline-2(1H)-carboximidamide;

Molecular form: C10H13N3
Appearance: NA
Mol. Weight: 175.24
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: An adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.

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