| Catalogue number: | PA 04 2781000 |
| Chemical name: | 4-Hydroxydebrisoquine |
CAS Number: |
59333-79-8 |
| Category: | impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals |
| Synonyms: | 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-4-hydroxy; 4-Hydroxy-3,4-dihydroisoquinoline-2(1H)-carboximidamide; |
| Molecular form: | C10H13N3O |
| Appearance: | NA |
| Mol. Weight: | 191.23 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | An adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism. |
4-Hydroxydebrisoquine
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