Aminopterin-α-hyrazide

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Catalogue number: PA 13 0281009
Chemical name: Aminopterin-α-hyrazide

CAS Number:

118359-33-4

Category: impurities,metabolites,pharmaceutical standards,intermediates,fine chemicals
Synonyms:

N5-Amino-N2-(4-((2,4-diaminopteridin-6-yl)(methyl)amino)benzoyl)-L-glutamine;

Molecular form: C19H22N10O4
Appearance: NA
Mol. Weight: 454.45
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Aminopterin-α-hyrazide, is derivative of Aminopterin (A628850), which is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.
BTM: NA

Aminopterin-α-hyrazide

118359-33-4
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