| Catalogue number: | PA 40 0571004 |
| Chemical name: | Sulfo-PDBA-DM4 |
CAS Number: |
1461704-01-7 |
| Category: | aromatics,chiral standards,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | Maytansine, N2′-[4-[(3-carboxy-3-sulfopropyl)dithio]-4-methyl-1-oxopentyl]-N2′-deacetyl-; N-2′-Deacetyl-N-2′-[4-methyl-4-(3-carboxy-3-sulfopropyldithio)-1-oxopentyl]maytansine; Soravtansine; 4-((5-(((S)-1-(((14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-2-methyl-5-oxopentan-2-yl)disulfaneyl)-2-sulfobutanoic acid; |
| Molecular form: | C42H60ClN3O15S3 |
| Appearance: | NA |
| Mol. Weight: | 978.58 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Sulfo-PDBA-DM4 is a agent-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody agent conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker |
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