Maytansine and its Impurities
Maytansine is a cytotoxic agent.It is a potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at sub-nanomolar concentrations. Reference standards of Maytansine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(14S,16S,32S,33S,4S,10E,12E,14R)-86-Chloro-14-hydroxy-85,14-dimethoxy-33,2,2,7,10-pentamethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(4-mercapto-4-methylpentanoyl)-N-methyl-L-alaninate
(14S,16S,32S,33S,4S,10E,12E,14R)-86-Chloro-14-hydroxy-85,14-dimethoxy-33,2,2,7,10-pentamethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(4-mercapto-4-methylpentanoyl)-N-methyl-L-alaninate
Catalogue No.:PA 40 0571016
CAS :
799840-96-3
Molecular Formula : C39H56ClN3O10S
Molecular Weight : 794.4
