| Catalogue number: | PA 03 0061018 |
| Chemical name: | CL2E-SN38 |
CAS Number: |
1639139-65-3 |
| Category: | pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | 4-((2S,5S)-2-(4-aminobutyl)-5-benzyl-38-(4-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carboxamido)methyl)-1H-1,2,3-triazol-1-yl)-4,7,11-trioxo-9,15,18,21,24,27,30,33,36-nonaoxa-3,6,12-triazaoctatriacontanamido)benzyl ((S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl) ethane-1,2-diylbis(methylcarbamate); L-Lysinamide, N-[32-[4-[[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]methyl]-1H-1,2,3-triazol-1-yl]-1,5-dioxo-3,9,12,15,18,21,24,27,30-nonaoxa-6-azadotriacont-1-yl]-L-phenylalanyl-N-[4-[[[[[2-[[[[(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-14-oxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl]oxy]carbonyl]methylamino]ethyl]methylamino]carbonyl]oxy]methyl]phenyl]-; N-[32-[4-[[[[4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]methyl]-1H-1,2,3-triazol-1-yl]-1,5-dioxo-3,9,12,15,18,21,24,27,30-nonaoxa-6-azadotriacont-1-yl]-L-phenylalanyl-N-[4-[[[[[2-[[[[(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-14-oxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl]oxy]carbonyl]methylamino]ethyl]methylamino]carbonyl]oxy]methyl]phenyl]-L-lysinamide; |
| Molecular form: | C87H116N14O24 |
| Appearance: | NA |
| Mol. Weight: | 1741.96 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor |
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