| Catalogue number: | PA 05 1991009 |
| Chemical name: | NH2-methylpropanamide-Exatecan TFA |
CAS Number: |
1817857-35-4 |
| Category: | Fine Chemicals,pharmaceutical standards,metabolites,impurities,intermediates,Antibody Drug Conjugate |
| Synonyms: | (S)-3-Amino-N-((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)-2-methylpropanamide 2,2,2-trifluoroacetate; Propanamide, 3-amino-N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]-2-methyl-, (2S)-, 2,2,2-trifluoroacetate (1:1); |
| Molecular form: | C30H30F4N4O7 |
| Appearance: | Solid |
| Mol. Weight: | 634.58 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | NH2-methylpropanamide-Exatecan TFA is a methylpropanamide-modified Exatecan (HY-13631), which is the common ADC Cytotoxin used in the synthesis of ADC. Exatecan is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research |
NH2-methylpropanamide-Exatecan TFA
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