Catalogue number: | PA 05 0721001 |
Chemical name: | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole |
CAS Number: |
210690-85-0 |
Category: | chiral standards,pharmaceutical standards,impurities,metabolites,fine chemicals |
Synonyms: | 4-((1E,3S,5Z,10S)-3,11-bis((tert-butyldimethylsilyl)oxy)-2,6,10-trimethylundeca-1,5-dien-1-yl)-2-methylthiazole; |
Molecular form: | C30H57NO2SSi2 |
Appearance: | Colourless Oil |
Mol. Weight: | 552.02 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | An intermediate in the synthesis of Epothilones. Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers. |
BTM: | NA |
4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
In House ImpurityEnquire for 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
Related Products
Search by Keywords – Buy 210690-85-0 | Purchase 210690-85-0 | Order 210690-85-0 | Enquire 210690-85-0 | Price of 210690-85-0 | 210690-85-0 Cost | 210690-85-0 Supplier | 210690-85-0 Distributor | 210690-85-0 Manufacturer | 210690-85-0 Exporter