| Catalogue number: | PA 03 0831004 |
| Chemical name: | 2-((2-Chloroethyl)(2-ethoxyethyl)amino)-1,3,2-oxazaphosphinane 2-oxide |
CAS Number: |
2387771-96-0 |
| Category: | impurities,metabolites,pharmaceutical standards,intermediates,fine chemicals |
| Synonyms: | 2H-1,3,2-Oxazaphosphorin-2-amine, N-(2-chloroethyl)-N-(2-ethoxyethyl)tetrahydro-, 2-oxide |
| Molecular form: | C9H20ClN2O3P |
| Appearance: | NA |
| Mol. Weight: | 270.69 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | N-(2-Chloroethyl)-N-(2-ethoxyethyl)tetrahydro-2H-1,3,2-Oxazaphosphorin-2-amine 2-Oxide is an impurity of Cyclophosphamide), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen. |
| BTM: | NA |
2-((2-Chloroethyl)(2-ethoxyethyl)amino)-1,3,2-oxazaphosphinane 2-oxide
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