| Catalogue number: | PA 05 1991012 |
| Chemical name: | Exatecan-amide-cyclopropanol |
CAS Number: |
2414254-34-3 |
| Category: | Fine Chemicals,pharmaceutical standards,metabolites,impurities,intermediates,Antibody Drug Conjugate |
| Synonyms: | N-((1S,9S)-9-Ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)-1-hydroxycyclopropane-1-carboxamide; Cyclopropanecarboxamide, N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]-1-hydroxy-; N-[(1S,9S)-9-Ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]-1-hydroxycyclopropanecarboxamide; |
| Molecular form: | C28H26FN3O6 |
| Appearance: | Solid |
| Mol. Weight: | 519.53 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Exatecan-amide-cyclopropanol (compound 1) is a anticancer agent. Exatecan-amide-cyclopropanol shows anti-proliferation activity against SK-BR-3 and U87 cells, with IC50 values of 0.12 and 0.23 nM, respectively |
Exatecan-amide-cyclopropanol
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