| Catalogue number: | PA 03 0061027 |
| Chemical name: | MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin |
CAS Number: |
2414594-29-7 |
| Category: | pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((9S,12S,15S)-1-((S)-4-ethyl-8-fluoro-4-hydroxy-9-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-11-yl)-9,12-dimethyl-3,8,11,14-tetraoxo-5-oxa-2,7,10,13-tetraazahexadecan-15-yl)hexanamide; L-Alaninamide, N-[6-(2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-alanyl-L-alanyl-N-[[2-[[[(4S)-4-ethyl-8-fluoro-3,4,12,14-tetrahydro-4-hydroxy-9-methyl-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-11-yl]methyl]amino]-2-oxoethoxy]methyl]-; |
| Molecular form: | C44H51FN8O12 |
| Appearance: | Solid |
| Mol. Weight: | 902.93 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC) |
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin
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