Catalogue number: | PA 05 1991020 |
Chemical name: | MC-VA-PAB-Exatecan |
CAS Number: |
2680543-57-9 |
Category: | Fine Chemicals,pharmaceutical standards,metabolites,impurities,intermediates,Antibody Drug Conjugate |
Synonyms: | 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)propanamido)benzyl ((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)carbamate; |
Molecular form: | C50H54FN7O11 |
Appearance: | NA |
Mol. Weight: | 948.02 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity |
MC-VA-PAB-Exatecan
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