| Catalogue number: | PA 08 0131052 |
| Chemical name: | Glucocorticoid receptor modulator 4 |
CAS Number: |
2688785-30-8 |
| Category: | pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | (8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl 3-((S)-2-((S)-2-(2-bromoacetamido)propanamido)propanamido)-4-fluorobenzoate; |
| Molecular form: | C37H43BrF3N3O8S |
| Appearance: | NA |
| Mol. Weight: | 826.72 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Glucocorticoid receptor modulator 4 (Compound DL5) is a conjugate of a linker and a glucocorticoid receptor modulator. Glucocorticoid receptor modulator 4 exhibits GRE Reporter activity in mTNF expressing K562 cell with an EC50 of 40 μM. Glucocorticoid receptor modulator 4 binds with an anti-tumor necrosis factor (TNF) antibody, and exhibits anti-inflammtory activity against arthritis in mouse models |
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