Catalogue number: | PA PEP 003151 |
Chemical name: | DBCO-PEG4-GGFG-Dxd |
CAS Number: |
2694856-51-2 |
Category: | peptides,Antibody Drug Conjugate |
Synonyms: | NA |
Molecular form: | C72H79FN10O17 |
Appearance: | Solid |
Mol. Weight: | 1375.48 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG[1]. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. |
DBCO-PEG4-GGFG-Dxd
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