7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)

In House Impurity

Stock Status : <%stockStatus%>

<%deliveryStatus%>

Catalogue number:	PA 03 0061043
Chemical name:	7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)
CAS Number:	2873460-17-2
Category:	pharmaceutical standards,Intermediates,Fine Chemicals,Antibody Drug Conjugate
Synonyms:	2-Hydroxyethyl (S)-((4-ethyl-8-fluoro-4-hydroxy-9-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-11-yl)methyl)carbamate; ZD 06519;
Molecular form:	C₂₅H₂₄FN₃O₇
Appearance:	Solid
Mol. Weight:	497.48
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	ZD06519 (7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)) is a camptothecin (HY-16560) analogue and a topoisomerase I inhibitor. ZD06519 is an ADC cytotoxin with a strong bystander effect, inhibiting a variety of malignancies such as HER2-positive and FRα-overexpressing tumors. ZD06519 inhibits DNA cleavage, relaxation, and reconnection processes, inducing tumor cell death. ZD06519 can be used for ADC synthesis and cancer research