Catalogue number: | PA 09 0151000 |
Chemical name: | 1-(2-Amino-5-hydroxyphenyl)propan-1-one |
CAS Number: |
35364-15-9 |
Category: | impurities,metabolites,intermediates,pharmaceutical standards,fine chemicals |
Synonyms: | 2'-Amino-5'-hydroxypropiophenone; Irinotecan - In house impurity |
Molecular form: | C9H11NO2 |
Appearance: | Yellow to Beige Solid |
Mol. Weight: | 165.19 |
Storage: | 2-8°C Refrigerator, Under inert atmosphere |
Shipping Conditions: | Ambient |
Applications: | 1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-ring-modified (RS)-camptothecin analogs as antitumor agents. |
BTM: | NA |
1-(2-Amino-5-hydroxyphenyl)propan-1-one
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