irinotecan and its Impurities

Irinotecan main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. It is sold under the brand name Camptosar. Reference standards of Irinotecan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 40 results for irinotecan Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 09 15000

Irinotecan

Irinotecan

  • Catalogue No.:PA 09 15000

  • CAS :

    97682-44-5

  • Molecular Formula : C33H38N4O6

  • Molecular Weight : 586.68

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Drug Reference Standards & Impurity Synthesis in India
PA 09 16510

Irinotecan Keto Impurity

Irinotecan Keto Impurity

  • Catalogue No.:PA 09 16510

  • CAS :

    176515-52-9

  • Molecular Formula : C32H38N4O4

  • Molecular Weight : 542.67

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Drug Reference Standards & Impurity Synthesis in India
PA 09 16520

Irinotecan Acid Sodium Salt

Irinotecan Acid Sodium Salt

  • Catalogue No.:PA 09 16520

  • CAS :

    1329502-92-2

  • Molecular Formula : C33H39N4NaO7

  • Molecular Weight : 626.68

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Drug Reference Standards & Impurity Synthesis in India
PA 09 16540

Irinotecan 2-Hydroxy Impurity

Irinotecan 2-Hydroxy Impurity

  • Catalogue No.:PA 09 16540

  • CAS :

    1346597-39-4

  • Molecular Formula : C33H38N4O7

  • Molecular Weight : 602.68

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Drug Reference Standards & Impurity Synthesis in India
PA 09 16550

Irinotecan Lactone Impurity

Irinotecan Lactone Impurity

  • Catalogue No.:PA 09 16550

  • CAS :

    143490-53-3

  • Molecular Formula : C32H36N4O5

  • Molecular Weight : 556.65

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Drug Reference Standards & Impurity Synthesis in India
PA 09 16570

4-Ethyl-4-hydroxy-11-isopropyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate;

4-Ethyl-4-hydroxy-11-isopropyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate;

  • Catalogue No.:PA 09 16570

  • CAS :

    NA

  • Molecular Formula : C34H40N4O6

  • Molecular Weight : 600.7

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Drug Reference Standards & Impurity Synthesis in India
PA 09 16580

rac-Desmethyl Irinotecan Hydrochloride

rac-Desmethyl Irinotecan Hydrochloride

  • Catalogue No.:PA 09 16580

  • CAS :

    NA

  • Molecular Formula : C32H37ClN4O6

  • Molecular Weight : 609.11

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Drug Reference Standards & Impurity Synthesis in India
PA 09 16590

(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline 6-oxide

(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline 6-oxide

  • Catalogue No.:PA 09 16590

  • CAS :

    86639-51-2

  • Molecular Formula : C22H20N2O5

  • Molecular Weight : 392.41

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Drug Reference Standards & Impurity Synthesis in India
PA STI 003450

10-O-Acetyl SN-38-d3

10-O-Acetyl SN-38-d3

  • Catalogue No.:PA STI 003450

  • CAS :

    NA

  • Molecular Formula : C24H19D3N2O6

  • Molecular Weight : 437.46

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Drug Reference Standards & Impurity Synthesis in India
PA STI 027330

11-Desethyl Irinotecan-d10

11-Desethyl Irinotecan-d10

  • Catalogue No.:PA STI 027330

  • CAS :

    NA

  • Molecular Formula : C31H24D10N4O6

  • Molecular Weight : 568.69

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Drug Reference Standards & Impurity Synthesis in India
PA STI 038750

7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3

7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3

  • Catalogue No.:PA STI 038750

  • CAS :

    1217816-76-6

  • Molecular Formula : C33H35D3N4O8

  • Molecular Weight : 621.70

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Drug Reference Standards & Impurity Synthesis in India
PA STI 038760

7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3

7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3

  • Catalogue No.:PA STI 038760

  • CAS :

    1217625-98-3

  • Molecular Formula : C28H27D3N4O6

  • Molecular Weight : 521.58

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Drug Reference Standards & Impurity Synthesis in India
PA STI 049410

2-Hydroxy Irinotecan-d10

2-Hydroxy Irinotecan-d10

  • Catalogue No.:PA STI 049410

  • CAS :

    1346597-30-5

  • Molecular Formula : C33H28D10N4O7

  • Molecular Weight : 612.74

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Drug Reference Standards & Impurity Synthesis in India
PA STI 053600

Irinotecan-d10 Hydrochloride

Irinotecan-d10 Hydrochloride

  • Catalogue No.:PA STI 053600

  • CAS :

    NA

  • Molecular Formula : C33H29D10ClN4O6

  • Molecular Weight : 633.20

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001830

Irinotecan for system suitability 1 (Y0001830)

Irinotecan for system suitability 1 (Y0001830)

  • Catalogue No.:PA EPY0001830

  • CAS :

    136572-09-3

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001831

Irinotecan for peak identification (Y0001831)

Irinotecan for peak identification (Y0001831)

  • Catalogue No.:PA EPY0001831

  • CAS :

    136572-09-3

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001832

Irinotecan hydrochloride trihydrate (Y0001832)

Irinotecan hydrochloride trihydrate (Y0001832)

  • Catalogue No.:PA EPY0001832

  • CAS :

    136572-09-3

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001833

Irinotecan for system suitability 2 (Y0001833)

Irinotecan for system suitability 2 (Y0001833)

  • Catalogue No.:PA EPY0001833

  • CAS :

    136572-09-3

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1347609

Irinotecan Hydrochloride (1347609)

Irinotecan Hydrochloride (1347609)

  • Catalogue No.:PA USP1347609

  • CAS :

    136572-09-3

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1347610

Irinotecan Related Compound A ((S)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quino (1347610)

Irinotecan Related Compound A ((S)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quino (1347610)

  • Catalogue No.:PA USP1347610

  • CAS :

    19685-09-7

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1347631

Irinotecan Related Compound B ((S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b] (1347631)

Irinotecan Related Compound B ((S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b] (1347631)

  • Catalogue No.:PA USP1347631

  • CAS :

    86639-52-3

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1347642

Irinotecan Related Compound C (11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyran (1347642)

Irinotecan Related Compound C (11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyran (1347642)

  • Catalogue No.:PA USP1347642

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1347653

Irinotecan Related Compound D ((R)-9-[(1,4'-Bipiperidine)-1'-carbonyloxy]-4,11-diethyl-3,4,12,14-te (1347653)

Irinotecan Related Compound D ((R)-9-[(1,4'-Bipiperidine)-1'-carbonyloxy]-4,11-diethyl-3,4,12,14-te (1347653)

  • Catalogue No.:PA USP1347653

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1347664

Irinotecan Related Compound E ((S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quin (1347664)

Irinotecan Related Compound E ((S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quin (1347664)

  • Catalogue No.:PA USP1347664

  • CAS :

    78287-27-1

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PAI 09 008010

(S)-8-Bromo-4,11-diethyl-4,9-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

(S)-8-Bromo-4,11-diethyl-4,9-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

  • Catalogue No.:PAI 09 008010

  • CAS :

    NA

  • Molecular Formula : C22H19BrN2O5

  • Molecular Weight : 471.31

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151000

1-(2-Amino-5-hydroxyphenyl)propan-1-one

1-(2-Amino-5-hydroxyphenyl)propan-1-one

  • Catalogue No.:PA 09 0151000

  • CAS :

    35364-15-9

  • Molecular Formula : C9H11NO2

  • Molecular Weight : 165.19

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0161000

4-Piperidinopiperidine-1-carbonyl Chloride

4-Piperidinopiperidine-1-carbonyl Chloride

  • Catalogue No.:PA 09 0161000

  • CAS :

    103816-19-9

  • Molecular Formula : C11H19ClN2O

  • Molecular Weight : 230.74

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Drug Reference Standards & Impurity Synthesis in India
PA STI 088709

Irinotecan-d10 Hydrochloride (Major)

Irinotecan-d10 Hydrochloride (Major)

  • Catalogue No.:PA STI 088709

  • CAS :

    718612-62-5

  • Molecular Formula : C33H29D10ClN4O6

  • Molecular Weight : 633.21

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151001

(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 2'-ethoxy-[1,4'-bipiperidine]-1'-carboxylate

(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 2'-ethoxy-[1,4'-bipiperidine]-1'-carboxylate

  • Catalogue No.:PA 09 0151001

  • CAS :

    NA

  • Molecular Formula : C35H42N4O7

  • Molecular Weight : 630.74

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151002

(4S)-4,11-Diethyl-4,9,12-trihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

(4S)-4,11-Diethyl-4,9,12-trihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

  • Catalogue No.:PA 09 0151002

  • CAS :

    200619-21-2

  • Molecular Formula : C22H20N2O6

  • Molecular Weight : 408.41

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151003

2'-Ethoxy-[1,4'-bipiperidine]-1'-carbonyl Chloride

2'-Ethoxy-[1,4'-bipiperidine]-1'-carbonyl Chloride

  • Catalogue No.:PA 09 0151003

  • CAS :

    NA

  • Molecular Formula : C13H23ClN2O2

  • Molecular Weight : 274.79

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151004

2'-hydroxy-[1,4'-bipiperidine]-1'-carbonyl chloride

2'-hydroxy-[1,4'-bipiperidine]-1'-carbonyl chloride

  • Catalogue No.:PA 09 0151004

  • CAS :

    NA

  • Molecular Formula : C11H19ClN2O2

  • Molecular Weight : 246.74

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151005

SN-38 Tri-O-acetyl-β-D-glucuronic acid methyl ester

SN-38 Tri-O-acetyl-β-D-glucuronic acid methyl ester

  • Catalogue No.:PA 09 0151005

  • CAS :

    121098-77-9

  • Molecular Formula : C35H36N2O14

  • Molecular Weight : 708.67

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151006

(S)-12-Ethyl-8-(hydroxymethyl)-7-(1-hydroxypropyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate

(S)-12-Ethyl-8-(hydroxymethyl)-7-(1-hydroxypropyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate

  • Catalogue No.:PA 09 0151006

  • CAS :

    185304-41-0

  • Molecular Formula : C32H40N4O5

  • Molecular Weight : 560.7

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0150070

Irinotecan - Impurity G (Hydrochloride Salt)

7,11-Diethyl-10-hydroxycamptothecin Hydrochloride

  • Catalogue No.:PA 09 0150070

  • CAS :

    NA

  • Molecular Formula : C24H25ClN2O5

  • Molecular Weight : 456.92

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151007

Sodium (S)-2-(12-ethyl-8-(hydroxymethyl)-2-oxido-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoate

Sodium (S)-2-(12-ethyl-8-(hydroxymethyl)-2-oxido-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoate

  • Catalogue No.:PA 09 0151007

  • CAS :

    NA

  • Molecular Formula : C22H20N2Na2O6

  • Molecular Weight : 454.39

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0160011

Irinotecan - Impurity A (Hydrochloride Trihydrate Salt)

(S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate hydrochloride trihydrate

  • Catalogue No.:PA 09 0160011

  • CAS :

    158406-44-1

  • Molecular Formula : C31H41ClN4O9

  • Molecular Weight : 649.14

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151008

1'-Nitroso-1,4'-bipiperidine

1'-Nitroso-1,4'-bipiperidine

  • Catalogue No.:PA 09 0151008

  • CAS :

    2639422-25-4

  • Molecular Formula : C10H19N3O

  • Molecular Weight : 197.28

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151009

(S)-6-(([1,4'-Bipiperidine]-1'-carbonyl)oxy)-4-ethyl-2-(4-ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridin-6-yl)quinoline-3-carboxylic Acid

(S)-6-(([1,4'-Bipiperidine]-1'-carbonyl)oxy)-4-ethyl-2-(4-ethyl-4-hydroxy-3,8-dioxo-3,4,7,8-tetrahydro-1H-pyrano[3,4-c]pyridin-6-yl)quinoline-3-carboxylic Acid

  • Catalogue No.:PA 09 0151009

  • CAS :

    2252499-29-7

  • Molecular Formula : C33H38N4O8

  • Molecular Weight : 618.69

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0151010

(S)-2-(12-Ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic Acid

(S)-2-(12-Ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic Acid

  • Catalogue No.:PA 09 0151010

  • CAS :

    142677-15-4

  • Molecular Formula : C22H22N2O6

  • Molecular Weight : 410.43

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