| Catalogue number: | PA 18 26000 |
| Chemical name: | Rapamycin |
CAS Number: |
53123-88-9 |
| Category: | Fine Chemicals,enzyme inhibitors,pharmaceutical standards,heterocycles,intermediates,chiral standards |
| Synonyms: | Everolimus - Impurity A (EP/BP); (-)-Rapamycin; Sirolimus; (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12- [(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17, 21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28- tetraene-2,3,10,14,20-pentone; |
| Molecular form: | C51H79NO13 |
| Appearance: | White to Pale Yellow Solid |
| Mol. Weight: | 914.17 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Rapamycin is also known as Sirolimus which is a naturally occurring triene macrolide antibiotic , used to prevent organ transplant rejection and for the treatment of lymphangioleiomyomatosis (LAM). Rapamycin was also initially used as anti fungal agent. It works by inhibiting the activation of T cells and B cells by reducing the production of interleukin-2. |
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