Rilpivirine-impurities | Pharmaffiliates

rilpivirine and its Impurities

A second-generation non-nucleoside reverse transcriptase inhibitor drug, Rilpivrine is used for the treatment of HIV/AIDS. A diarylpyrimidine derivative.Reference standards of Rilpivirine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 45 results for rilpivirine Impurities
PA 18 22510

4-[(4-Chloropyrimidin-2-yl)amino]-Benzonitrile

4-[(4-Chloropyrimidin-2-yl)amino]-Benzonitrile


  • Catalogue No.:PA 18 22510

  • CAS :

    244768-32-9

  • Molecular Formula : C11H7ClN4

  • Molecular Weight : 230.65

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PA 18 22520

4-[(4-Oxo-1, 4-Dihydropyrimidin-2-yl)amino]-Benzonitrile

4-[(4-Oxo-1, 4-Dihydropyrimidin-2-yl)amino]-Benzonitrile


  • Catalogue No.:PA 18 22520

  • CAS :

    189956-45-4

  • Molecular Formula : C11H8N4O

  • Molecular Weight : 212.21

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PA 18 22610

Rilpivirine N-Oxide

Rilpivirine N-Oxide


  • Catalogue No.:PA 18 22610

  • CAS :

    NA

  • Molecular Formula : C22H18N6O

  • Molecular Weight : 382.42

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PA 18 22670

(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride

(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride


  • Catalogue No.:PA 18 22670

  • CAS :

    661489-23-2

  • Molecular Formula : C11H13ClN2

  • Molecular Weight : 208.69

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PA 18 22000

Rilpivirine - API Standards

Rilpivirine


  • Catalogue No.:PA 18 22000

  • CAS :

    500287-72-9

  • Molecular Formula : C22H18N6

  • Molecular Weight : 366.42

PA 18 22530

2-Hydroxymethyl Rilpivirine

2-Hydroxymethyl Rilpivirine


  • Catalogue No.:PA 18 22530

  • CAS :

    1798429-64-7

  • Molecular Formula : C22H18N6O

  • Molecular Weight : 382.42

PA 18 22540

Rilpivirine N-Glucuronide

Rilpivirine N-Glucuronide


  • Catalogue No.:PA 18 22540

  • CAS :

    1437791-52-0

  • Molecular Formula : C28H26N6O6

  • Molecular Weight : 542.54

PA 18 22550

Despropenenitrile Bromo Rilpivirine

Despropenenitrile Bromo Rilpivirine


  • Catalogue No.:PA 18 22550

  • CAS :

    374067-85-3

  • Molecular Formula : C19H16BrN5

  • Molecular Weight : 394.27

PA 18 22560

(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile

(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile


  • Catalogue No.:PA 18 22560

  • CAS :

    661489-22-1

  • Molecular Formula : C11H12N2

  • Molecular Weight : 172.23

PA 18 22570

4-Nitroisophthalic Acid

4-Nitroisophthalic Acid


  • Catalogue No.:PA 18 22570

  • CAS :

    4315-09-7

  • Molecular Formula : C8H5NO6

  • Molecular Weight : 211.13

PA 18 22580

2-Nitroisophthalic Acid

2-Nitroisophthalic Acid


  • Catalogue No.:PA 18 22580

  • CAS :

    21161-11-5

  • Molecular Formula : C8H5NO6

  • Molecular Weight : 211.13

PA 18 22590

Rilpivirine Z-Isomer

Rilpivirine Z-Isomer


  • Catalogue No.:PA 18 22590

  • CAS :

    500287-94-5

  • Molecular Formula : C22H18N6

  • Molecular Weight : 366.42

PA 18 22600

Rilpivirine Z-Isomer Hydrochloride

Rilpivirine Z-Isomer Hydrochloride


  • Catalogue No.:PA 18 22600

  • CAS :

    1502822-82-3

  • Molecular Formula : C22H19ClN6

  • Molecular Weight : 402.88

PA STI 078050

Rilpivirine-d6

Rilpivirine-d6


  • Catalogue No.:PA STI 078050

  • CAS :

    1312424-26-2

  • Molecular Formula : C22H12D6N6

  • Molecular Weight : 372.46

PA 18 22620

4,4'-(Pyrimidine-2,4-diylbis(azanediyl))dibenzonitrile

4,4'-(Pyrimidine-2,4-diylbis(azanediyl))dibenzonitrile


  • Catalogue No.:PA 18 22620

  • CAS :

    1629023-90-0

  • Molecular Formula : C18H12N6

  • Molecular Weight : 312.34

PA IPIPRS 88 13

Rilpivirine (IPRS/88/13)-from IPC


  • Catalogue No.:PA IPIPRS 88 13

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA 18 22640

2-Amino-5-iodo-3-methylbenzoic Acid Methyl Ester

2-Amino-5-iodo-3-methylbenzoic Acid Methyl Ester


  • Catalogue No.:PA 18 22640

  • CAS :

    1096481-48-9

  • Molecular Formula : C9H10INO2

  • Molecular Weight : 291.09

PA 18 22650

2-Amino-5-iodo-3-methylbenzenemethanol

2-Amino-5-iodo-3-methylbenzenemethanol


  • Catalogue No.:PA 18 22650

  • CAS :

    108857-25-6

  • Molecular Formula : C8H10INO

  • Molecular Weight : 263.08

PA 18 22660

(E)-3-(4-((2-((4-Cyanophenyl)amino)pyrimidin-4-yl)amino)-3,5-dimethylphenyl)acrylamide

(E)-3-(4-((2-((4-Cyanophenyl)amino)pyrimidin-4-yl)amino)-3,5-dimethylphenyl)acrylamide


  • Catalogue No.:PA 18 22660

  • CAS :

    500288-66-4

  • Molecular Formula : C22H20N6O

  • Molecular Weight : 384.44

PA 18 0221000

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(methyl)amino)benzonitrile

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(methyl)amino)benzonitrile


  • Catalogue No.:PA 18 0221000

  • CAS :

    NA

  • Molecular Formula : C23H20N6

  • Molecular Weight : 380.46

PA 18 0221001

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)(methyl)amino)pyrimidin-2-yl)amino)benzonitrile

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)(methyl)amino)pyrimidin-2-yl)amino)benzonitrile


  • Catalogue No.:PA 18 0221001

  • CAS :

    NA

  • Molecular Formula : C23H20N6

  • Molecular Weight : 380.46

PA 18 0221002

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzamide

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzamide


  • Catalogue No.:PA 18 0221002

  • CAS :

    1446439-51-5

  • Molecular Formula : C22H20N6O

  • Molecular Weight : 384.44

PA 18 0221003

(E)-4-((4-((4-(2-Cyanovinyl)-2-methylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile

(E)-4-((4-((4-(2-Cyanovinyl)-2-methylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile


  • Catalogue No.:PA 18 0221003

  • CAS :

    500292-48-8

  • Molecular Formula : C21H16N6

  • Molecular Weight : 352.4

PA 18 0221005

(Z)-2-(4-((2-((4-Cyanophenyl)amino)pyrimidin-4-yl)amino)-3,5-dimethylbenzylidene)-3-(4-((2-((4-cyanophenyl)amino)pyrimidin-4-yl)amino)-3,5-dimethylphenyl)pentanedinitrile

(Z)-2-(4-((2-((4-Cyanophenyl)amino)pyrimidin-4-yl)amino)-3,5-dimethylbenzylidene)-3-(4-((2-((4-cyanophenyl)amino)pyrimidin-4-yl)amino)-3,5-dimethylphenyl)pentanedinitrile


  • Catalogue No.:PA 18 0221005

  • CAS :

    NA

  • Molecular Formula : C44H36N12

  • Molecular Weight : 732.86

PA 18 0221006

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)(3,4-dihydroxy-6-(hydroxymethyl)-5-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)pyrimidin-2-yl)amino)benzonitrile compound with (E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)(3,5,6-trihydroxy-2-oxo-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)amino)pyrimidin-2-yl)amino)benzonitrile (1:1)

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)(3,4-dihydroxy-6-(hydroxymethyl)-5-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)pyrimidin-2-yl)amino)benzonitrile compound with (E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)(3,5,6-trihydroxy-2-oxo-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)amino)pyrimidin-2-yl)amino)benzonitrile (1:1)


  • Catalogue No.:PA 18 0221006

  • CAS :

    NA

  • Molecular Formula : C34H38N6O10

  • Molecular Weight : 690.71

PA 18 0221007

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(3,4-dihydroxy-6-(hydroxymethyl)-5-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)benzonitrile compound with (E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(3,5,6-trihydroxy-2-oxo-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)amino)benzonitrile (1:1)

(E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(3,4-dihydroxy-6-(hydroxymethyl)-5-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)benzonitrile compound with (E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(3,5,6-trihydroxy-2-oxo-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)amino)benzonitrile (1:1)


  • Catalogue No.:PA 18 0221007

  • CAS :

    NA

  • Molecular Formula : C34H38N6O10

  • Molecular Weight : 690.71

PA 18 0221004

Rilpivirine E-Z mixture Isomer

Rilpivirine E-Z mixture Isomer


  • Catalogue No.:PA 18 0221004

  • CAS :

    620622-82-4

  • Molecular Formula : C22H18N6

  • Molecular Weight : 366.43

PA 18 0221008

Rilpivirine Methyl ester impurity

Rilpivirine Methyl ester impurity


  • Catalogue No.:PA 18 0221008

  • CAS :

    NA

  • Molecular Formula : C23H21N5O2

  • Molecular Weight : 399.45

PA 18 0221009

(E)-N-(2-((4-Cyanophenyl)amino)pyrimidin-4-yl)-N-(4-(2-cyanovinyl)-2,6-dimethylphenyl)nitrous amide

(E)-N-(2-((4-Cyanophenyl)amino)pyrimidin-4-yl)-N-(4-(2-cyanovinyl)-2,6-dimethylphenyl)nitrous amide


  • Catalogue No.:PA 18 0221009

  • CAS :

    NA

  • Molecular Formula : C22H17N7O

  • Molecular Weight : 395.43

PA STI 089013

Rilpivirine-D6 HCl

Rilpivirine-D6 HCl


  • Catalogue No.:PA STI 089013

  • CAS :

    NA

  • Molecular Formula : C22H13D6ClN6

  • Molecular Weight : 408.92

PA 18 0221010

3-((4-Chloropyrimidin-2-yl)amino)benzamide

3-((4-Chloropyrimidin-2-yl)amino)benzamide


  • Catalogue No.:PA 18 0221010

  • CAS :

    1009330-41-9

  • Molecular Formula : C11H9ClN4O

  • Molecular Weight : 248.67

PA 18 0221012

Rilpivirine Iodo Impurity

Rilpivirine Iodo Impurity


  • Catalogue No.:PA 18 0221012

  • CAS :

    661489-24-3

  • Molecular Formula : C19H16IN5

  • Molecular Weight : 441.28

PA 18 0221013

Rilpivirine Dimethyl Phenyl Impurity

Rilpivirine Dimethyl Phenyl Impurity


  • Catalogue No.:PA 18 0221013

  • CAS :

    244768-59-0

  • Molecular Formula : C19H17N5

  • Molecular Weight : 315.38

PA 18 0221014

Rilpivirine Dipyrimidinyl Impurity

Rilpivirine Dipyrimidinyl Impurity


  • Catalogue No.:PA 18 0221014

  • CAS :

    NA

  • Molecular Formula : C33H24N10

  • Molecular Weight : 560.63

PA 18 0221015

Dinitroso Rilpivirine

Dinitroso Rilpivirine


  • Catalogue No.:PA 18 0221015

  • CAS :

    NA

  • Molecular Formula : C22H16N8O2

  • Molecular Weight : 424.42

PA 18 0221011

3-(4-Amino-3,5-diethylphenyl)-2-propenenitrile

3-(4-Amino-3,5-diethylphenyl)-2-propenenitrile


  • Catalogue No.:PA 18 0221011

  • CAS :

    885453-58-7

  • Molecular Formula : C11H12N2O

  • Molecular Weight : 200.29

PA 18 0221016

(E)-N-(4-Cyanophenyl)-N-(4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)nitrous Amide

(E)-N-(4-Cyanophenyl)-N-(4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)nitrous Amide


  • Catalogue No.:PA 18 0221016

  • CAS :

    NA

  • Molecular Formula : C22H17N7O

  • Molecular Weight : 395.43

PA 18 0221017

3-(4-Amino-3,5-dimethylphenyl)acrylonitrile

3-(4-Amino-3,5-dimethylphenyl)acrylonitrile


  • Catalogue No.:PA 18 0221017

  • CAS :

    500292-86-4

  • Molecular Formula : C11H12N2

  • Molecular Weight : 172.23

PA 18 0221018

(Z)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)(methyl)amino)pyrimidin-2-yl)amino)benzonitrile

(Z)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)(methyl)amino)pyrimidin-2-yl)amino)benzonitrile


  • Catalogue No.:PA 18 0221018

  • CAS :

    NA

  • Molecular Formula : C23H20N6

  • Molecular Weight : 380.46

PA 18 0221019

(Z)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(methyl)amino)benzonitrile

(Z)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(methyl)amino)benzonitrile


  • Catalogue No.:PA 18 0221019

  • CAS :

    NA

  • Molecular Formula : C23H20N6

  • Molecular Weight : 380.46

PA 18 0221020

(Z)-3-(3 | 5-Dimethyl-4-(methylamino)phenyl)acrylonitrile

(Z)-3-(3 | 5-Dimethyl-4-(methylamino)phenyl)acrylonitrile


  • Catalogue No.:PA 18 0221020

  • CAS :

    NA

  • Molecular Formula : C12H14N2

  • Molecular Weight : 186.26

PA 18 0221021

4,4'-((((3,3',5,5'-Tetramethyl-[1,1'-biphenyl]-4,4'-diyl)bis(azanediyl))bis(pyrimidine-4,2-diyl))bis(azanediyl))dibenzonitrile Dihydrochloride

4,4'-((((3,3',5,5'-Tetramethyl-[1,1'-biphenyl]-4,4'-diyl)bis(azanediyl))bis(pyrimidine-4,2-diyl))bis(azanediyl))dibenzonitrile Dihydrochloride


  • Catalogue No.:PA 18 0221021

  • CAS :

    NA

  • Molecular Formula : C38H34Cl2N10

  • Molecular Weight : 701.66

PA 18 0221022

(E)-3-(4-Amino-3-methylphenyl)acrylonitrile

(E)-3-(4-Amino-3-methylphenyl)acrylonitrile


  • Catalogue No.:PA 18 0221022

  • CAS :

    1862191-58-9

  • Molecular Formula : C10H10N2

  • Molecular Weight : 158.2

PA 18 0221023

(E)-3-(4-((2-Chloropyrimidin-4-yl)amino)-3,5-dimethylphenyl)acrylonitrile

(E)-3-(4-((2-Chloropyrimidin-4-yl)amino)-3,5-dimethylphenyl)acrylonitrile


  • Catalogue No.:PA 18 0221023

  • CAS :

    1538550-43-4

  • Molecular Formula : C15H13ClN4

  • Molecular Weight : 284.75

PA 18 0221024

Rilpivirine N-Oxide (E/Z Mixture)

Rilpivirine N-Oxide (E/Z Mixture)


  • Catalogue No.:PA 18 0221024

  • CAS :

    2734549-19-8

  • Molecular Formula : C22H18N6O

  • Molecular Weight : 382.43