bortezomib
Bortezomib was approved for medical use in the United States in 2003 and in Europe in 2004. Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma.. Reference standards of Bortezomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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[catalogue_number] => PA 02 79540
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[form] => C19H24N4O3
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N-(1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79540
Molecular Formula : C19H24N4O3
Molecular Weight : 356.42
stdClass Object
(
[pname] => Bortezomib Amide analog (Mixture of isomers)
[catalogue_number] => PA 02 79550
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[chemical_name] =>
[weight] => 270.29
[form] => C14H14N4O2
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Bortezomib Amide analog (Mixture of isomers)
Catalogue No.:PA 02 79550
Molecular Formula : C14H14N4O2
Molecular Weight : 270.29
stdClass Object
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[pname] => N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
[catalogue_number] => PA 02 79560
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[weight] => 340.42
[form] => C19H24N4O2
[cas] => 1446194-56-4
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N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
Catalogue No.:PA 02 79560
Molecular Formula : C19H24N4O2
Molecular Weight : 340.42
stdClass Object
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[pname] => N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
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N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79580
Molecular Formula : C19H24N4O2
Molecular Weight : 340.42
stdClass Object
(
[pname] => (4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid
[catalogue_number] => PA 02 79590
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[weight] => 386.21
[form] => C18H23BN4O5
[cas] => NA
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(4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid
Catalogue No.:PA 02 79590
Molecular Formula : C18H23BN4O5
Molecular Weight : 386.21
stdClass Object
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[pname] => N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
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[weight] => 504.43
[form] => C28H37BN4O4
[cas] => NA
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N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79600
Molecular Formula : C28H37BN4O4
Molecular Weight : 504.43
stdClass Object
(
[pname] => (R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid
[catalogue_number] => PA 02 79610
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[weight] => 285.3
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(R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid
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[weight] => 531.41
[form] => C28H34BN5O5
[cas] => NA
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((R)-3-Methyl-1-((S)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic Acid
Catalogue No.:PA 02 79680
Molecular Formula : C28H34BN5O5
Molecular Weight : 531.41
stdClass Object
(
[pname] => Bortezomib ((1R,2S)-Bortezomib)
[catalogue_number] => PA 02 79690
[category_ids] => ,90,69,70,
[chemical_name] =>
[weight] => 1098.67
[form] => C57H69B3N12O9
[cas] => 390800-88-1
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Bortezomib ((1R,2S)-Bortezomib)
Catalogue No.:PA 02 79690
Molecular Formula : C57H69B3N12O9
Molecular Weight : 1098.67
stdClass Object
(
[pname] => (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate
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[weight] => 518.46
[form] => C29H39BN4O4
[cas] => 205393-22-2
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(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate
Catalogue No.:PA 02 79700
Molecular Formula : C29H39BN4O4
Molecular Weight : 518.46
stdClass Object
(
[pname] => (R,R)-Hydroxy Des(boric Acid) Bortezomib
[catalogue_number] => PA 02 79710
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[chemical_name] =>
[weight] => 356.42
[form] => C19H24N4O3
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(R,R)-Hydroxy Des(boric Acid) Bortezomib
Catalogue No.:PA 02 79710
Molecular Formula : C19H24N4O3
Molecular Weight : 356.42
stdClass Object
(
[pname] => Bortezomib-D8 (Major)
[catalogue_number] => PA STI 014210
[category_ids] => ,69,90,81,78,70,82,98,
[chemical_name] =>
[weight] => 392.29
[form] => C19H17D8BN4O4
[cas] => NA
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Catalogue No.:PA STI 014210
Molecular Formula : C19H17D8BN4O4
Molecular Weight : 392.29
stdClass Object
(
[pname] => (1R,2R)-Bortezomib-d5
[catalogue_number] => PA STI 014220
[category_ids] => ,69,90,81,78,70,82,98,
[chemical_name] =>
[weight] => 389.27
[form] => C19H20D5BN4O4
[cas] => NA
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Catalogue No.:PA STI 014220
Molecular Formula : C19H20D5BN4O4
Molecular Weight : 389.27
stdClass Object
(
[pname] => (1S,2R)-Bortezomib-d5
[catalogue_number] => PA STI 014230
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[weight] => 389.27
[form] => C19H20D5BN4O4
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Catalogue No.:PA STI 014230
Molecular Formula : C19H20D5BN4O4
Molecular Weight : 389.27
stdClass Object
(
[pname] => (1S,2S)-Bortezomib-d5
[catalogue_number] => PA STI 014240
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[weight] => 389.27
[form] => C19H20D5BN4O4
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Catalogue No.:PA STI 014240
Molecular Formula : C19H20D5BN4O4
Molecular Weight : 389.27
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[catalogue_number] => PA STI 073740
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[chemical_name] =>
[weight] => 526.50
[form] => C29H31D8BN4O4
[cas] => NA
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(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methylbutane-1-boronate-d8
Catalogue No.:PA STI 073740
Molecular Formula : C29H31D8BN4O4
Molecular Weight : 526.50
stdClass Object
(
[pname] => Bortezomib L-Phenylalanyl Analog
[catalogue_number] => PA 02 79720
[category_ids] => 76,71,90,69,70,78,82,79,75
[chemical_name] =>
[weight] => 531.42
[form] => C28H34BN5O5
[cas] => 1194235-41-0
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Bortezomib L-Phenylalanyl Analog
Catalogue No.:PA 02 79720
Molecular Formula : C28H34BN5O5
Molecular Weight : 531.42
stdClass Object
(
[pname] => (αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
[catalogue_number] => PA 02 79750
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[chemical_name] =>
[weight] => 379.23
[form] => C17H29BF3NO4
[cas] => 179324-87-9
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(αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
Catalogue No.:PA 02 79750
Molecular Formula : C17H29BF3NO4
Molecular Weight : 379.23
stdClass Object
(
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(αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride
Catalogue No.:PA 02 79840
Molecular Formula : C23H36BClN2O3
Molecular Weight : 434.81
stdClass Object
(
[pname] => N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
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[weight] => 356.43
[form] => C19H24N4O3
[cas] => NA
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N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791038
Molecular Formula : C19H24N4O3
Molecular Weight : 356.43
stdClass Object
(
[pname] => (1-((S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanamido)pentyl)boronic Acid
[catalogue_number] => PA 02 0791041
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[weight] => 384.24
[form] => C19H25BN4O4
[cas] => NA
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(1-((S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanamido)pentyl)boronic Acid
Catalogue No.:PA 02 0791041
Molecular Formula : C19H25BN4O4
Molecular Weight : 384.24
stdClass Object
(
[pname] => N-(1-((1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
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[weight] => 356.43
[form] => C19H24N4O3
[cas] => 2984099-19-4
[pslug] => 2984099-19-4-n-1-1-hydroxy-3-methylbutyl-amino-1-oxo-3-phenylpropan-2-yl-pyrazine-2-carboxamide-pa020791042
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N-(1-((1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791042
Molecular Formula : C19H24N4O3
Molecular Weight : 356.43
stdClass Object
(
[pname] => rel-(R)-3-Methyl-1-((3aS,4R,6R,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate
[catalogue_number] => PA 02 0791043
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[weight] => 379.23
[form] => C17H29BF3NO4
[cas] => 1310383-72-2
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rel-(R)-3-Methyl-1-((3aS,4R,6R,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate
Catalogue No.:PA 02 0791043
Molecular Formula : C17H29BF3NO4
Molecular Weight : 379.23
stdClass Object
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[pname] => Bortezomib Mannitol
[catalogue_number] => PA 02 0791044
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[chemical_name] =>
[weight] => 530.39
[form] => C25H35BN4O8
[cas] => 444576-08-3
[pslug] => 444576-08-3-bortezomib-mannitol-pa020791044
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Catalogue No.:PA 02 0791044
Molecular Formula : C25H35BN4O8
Molecular Weight : 530.39
stdClass Object
(
[pname] => N-((R)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
[catalogue_number] => PA 02 0791045
[category_ids] => ,82,78,70,69,
[chemical_name] =>
[weight] => 372.43
[form] => C19H24N4O4
[cas] => NA
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N-((R)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791045
Molecular Formula : C19H24N4O4
Molecular Weight : 372.43
stdClass Object
(
[pname] => N-((R)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
[catalogue_number] => PA 02 0791046
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[chemical_name] =>
[weight] => 356.43
[form] => C19H24N4O3
[cas] => NA
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N-((R)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791046
Molecular Formula : C19H24N4O3
Molecular Weight : 356.43
stdClass Object
(
[pname] => (S)-2-Methyl-N-((S)-3-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butyl)propane-2-sulfinamide
[catalogue_number] => PA 02 0791047
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[chemical_name] =>
[weight] => 317.3
[form] => C15H32BNO3S
[cas] => NA
[pslug] => s-2-methyl-n-s-3-methyl-1-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-butyl-propane-2-sulfinamide-pa020791047
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(S)-2-Methyl-N-((S)-3-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butyl)propane-2-sulfinamide
stdClass Object
(
[pname] => (S)-3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine Hydrochloride
[catalogue_number] => PA 02 0791048
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[chemical_name] =>
[weight] => 249.59
[form] => C11H25BClNO2
[cas] => 2493017-06-2
[pslug] => 2493017-06-2-s-3-methyl-1-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-butan-1-amine-hydrochloride-pa020791048
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(S)-3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine Hydrochloride
Catalogue No.:PA 02 0791048
Molecular Formula : C11H25BClNO2
Molecular Weight : 249.59