ponatinib
Tyrosine kinase inhibitors
- A multi-targeted tyrosine-kinase inhibitor, Ponatinib is used in treating chronic myeloid leukemia. Shows antiangiogenic and antineoplastic activities.Reference standards of Ponatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Ponatinib
[catalogue_number] => PA 16 91000
[category_ids] => ,71,78,70,82,117,
[chemical_name] =>
[weight] => 532.56
[form] => C29H27F3N6O
[cas] => 943319-70-8
[pslug] => 943319-70-8-ponatinib-api-pa1691000
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Catalogue No.:PA 16 91000
Molecular Formula : C29H27F3N6O
Molecular Weight : 532.56
stdClass Object
(
[pname] => 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
[catalogue_number] => PA 16 0911002
[category_ids] => ,71,78,70,82,117,
[chemical_name] =>
[weight] => 277.28
[form] => C16H11N3O2
[cas] => 1300690-48-5
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3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
Catalogue No.:PA 16 0911002
Molecular Formula : C16H11N3O2
Molecular Weight : 277.28
stdClass Object
(
[pname] => Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate
[catalogue_number] => PA 16 0911003
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[chemical_name] =>
[weight] => 291.31
[form] => C17H13N3O2
[cas] => 1356385-96-0
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Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate
Catalogue No.:PA 16 0911003
Molecular Formula : C17H13N3O2
Molecular Weight : 291.31
stdClass Object
(
[pname] => 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
[catalogue_number] => PA 16 0911004
[category_ids] => ,71,78,70,82,117,
[chemical_name] =>
[weight] => 273.3
[form] => C13H18F3N3
[cas] => 694499-26-8
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4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
stdClass Object
(
[pname] => Ponatinib N-beta-D-Glucuronide
[catalogue_number] => PA 16 0911008
[category_ids] => ,71,78,70,82,117,
[chemical_name] =>
[weight] => 789.61
[form] => C35H36BrF3N6O7
[cas] => NA
[pslug] => ponatinib-n-beta-d-glucuronide-pa160911008
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Ponatinib N-beta-D-Glucuronide
Catalogue No.:PA 16 0911008
Molecular Formula : C35H36BrF3N6O7
Molecular Weight : 789.61
stdClass Object
(
[pname] => Methyl 3-iodo-4-methylbenzoate
[catalogue_number] => PA 16 0911009
[category_ids] => ,71,78,70,82,117,
[chemical_name] =>
[weight] => 276.07
[form] => C9H9IO2
[cas] => 90347-66-3
[pslug] => 90347-66-3-methyl-3-iodo-4-methylbenzoate-pa160911009
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Methyl 3-iodo-4-methylbenzoate
Catalogue No.:PA 16 0911009
Molecular Formula : C9H9IO2
Molecular Weight : 276.07
stdClass Object
(
[pname] => 7-((Triisopropylsilyl)ethynyl)-3H-imidazo[4,5-b]pyridine
[catalogue_number] => PA 16 0911010
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[chemical_name] =>
[weight] => 299.49
[form] => C17H25N3Si
[cas] => 2500888-31-1
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7-((Triisopropylsilyl)ethynyl)-3H-imidazo[4,5-b]pyridine
Catalogue No.:PA 16 0911010
Molecular Formula : C17H25N3Si
Molecular Weight : 299.49
stdClass Object
(
[pname] => 4-(4-(3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamido)-2-(trifluoromethyl)benzyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)piperazine-1-carboxamide
[catalogue_number] => PA 16 0911012
[category_ids] => ,71,78,70,82,117,
[chemical_name] =>
[weight] => 817.84
[form] => C42H41F6N9O2
[cas] => NA
[pslug] => 4-4-3-imidazo-1-2-b-pyridazin-3-ylethynyl-4-methylbenzamido-2-trifluoromethyl-benzyl-n-4-4-methylpiperazin-1-yl-methyl-3-trifluoromethyl-phenyl-piperazine-1-carboxamide-pa160911012
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4-(4-(3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamido)-2-(trifluoromethyl)benzyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)piperazine-1-carboxamide
Catalogue No.:PA 16 0911012
Molecular Formula : C42H41F6N9O2
Molecular Weight : 817.84
