| Catalogue number: | PA 40 0421007 |
| Chemical name: | DM3-SMe |
CAS Number: |
796073-70-6 |
| Category: | sulphur and selenium compounds,Fine Chemicals,aromatics,amines,pharmaceutical standards,Heterocycles,Intermediates,Antibody Drug Conjugate |
| Synonyms: | Maytansine, N2′-deacetyl-N2′-[4-(methyldithio)-1-oxopentyl]; |
| Molecular form: | C38H54ClN3O10S2 |
| Appearance: | NA |
| Mol. Weight: | 812.43 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with an IC50 of 0.0011 nM |
DM3-SMe
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