| Catalogue number: | PA 40 0571000 |
| Chemical name: | DM4-SMCC |
CAS Number: |
1228105-52-9 |
| Category: | aromatics,chiral standards,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | Maytansine, N2′-deacetyl-N2′-[4-[[1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-4-methyl-1-oxopentyl]-; 2,5-dioxopyrrolidin-1-yl 4-((3-((5-(((S)-1-(((14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-2-methyl-5-oxopentan-2-yl)thio)-2,5-dioxopyrrolidin-1-yl)methyl)cyclohexane-1-carboxylate; |
| Molecular form: | C54H72ClN5O16S |
| Appearance: | Solid |
| Mol. Weight: | 1114.7 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | DM4-SMCC is a agent-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker |
DM4-SMCC
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