| Catalogue number: | PA 05 1991008 |
| Chemical name: | DXD |
CAS Number: |
1599440-33-1 |
| Category: | Fine Chemicals,pharmaceutical standards,metabolites,impurities,intermediates,Antibody Drug Conjugate |
| Synonyms: | Acetamide, N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]-2-hydroxy-; N-[(1S,9S)-9-Ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]-2-hydroxyacetamide; DX 8951; |
| Molecular form: | C26H24FN3O6 |
| Appearance: | Solid |
| Mol. Weight: | 493.49 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a). |
DXD
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