acitretin and its Impurities
A metabolite of etretinate, Acitretin is used in the treatment of psoriosis.It is sold under the trade name of Soriatane and Neotigason. Reference standards of Acitretin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


(2E,4E,6E,8E)-Isopropyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
(2E,4E,6E,8E)-Isopropyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
Catalogue No.:PA 28 03520
CAS :
74479-46-2
Molecular Formula : C24H32O3
Molecular Weight : 368.51


Butyl [(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethyl)phenyl-3,7-dimethylnona-2,4,6,8]tetraenoate
Butyl [(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethyl)phenyl-3,7-dimethylnona-2,4,6,8]tetraenoate
Catalogue No.:PA 28 03530
CAS :
74479-40-6
Molecular Formula : C25H34O3
Molecular Weight : 382.54


(2E,4E,6E,8E)-3-Ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-7-methylnona-2,4,6,8-tetraenoic Acid
(2E,4E,6E,8E)-3-Ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-7-methylnona-2,4,6,8-tetraenoic Acid
Catalogue No.:PA 28 03540
CAS :
1313741-10-4
Molecular Formula : C22H28O3
Molecular Weight : 340.46


4,4'-((1E,3E,5Z,7E,9E)-3,8-Dimethyldeca-1,3,5,7,9-pentaene-1,10-diyl)bis(1-methoxy-2,3,5-trimethylbenzene)
4,4'-((1E,3E,5Z,7E,9E)-3,8-Dimethyldeca-1,3,5,7,9-pentaene-1,10-diyl)bis(1-methoxy-2,3,5-trimethylbenzene)
Catalogue No.:PA 28 03550
CAS :
NA
Molecular Formula : C32H40O2
Molecular Weight : 456.66


Acitretin Related Compound B (ethyl (all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2, (1011029)
Acitretin Related Compound B (ethyl (all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2, (1011029)
Catalogue No.:PA USP1011029
CAS :
54350-48-0
Molecular Formula : NA
Molecular Weight : NA


Acitretin Related Compound A ((2Z,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2, (1011018)
Acitretin Related Compound A ((2Z,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2, (1011018)
Catalogue No.:PA USP1011018
CAS :
69427-46-9
Molecular Formula : NA
Molecular Weight : NA