adapalene and its Impurities

Adapalene is marketed by Galderma under the trade names Differin and Adaferin. It is a member of the retinoid drug class that is typically found in topical formulations used for the treatment of acne. It may be used to treat keratosis pilaris as well as other skin conditions as off-label use. Reference standards of Adapalene API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 43 results for adapalene Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 01 22000

Adapalene

Adapalene

  • Catalogue No.:PA 01 22000

  • CAS :

    106685-40-9

  • Molecular Formula : C28H28O3

  • Molecular Weight : 412.53

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Drug Reference Standards & Impurity Synthesis in India
PA 01 22010

Adapalene - Impurity A

2,2′-Binaphthalene-6,6′-dicarboxylic Acid

Drug Reference Standards & Impurity Synthesis in India

  • Catalogue No.:PA 01 22010

  • CAS :

    932033-58-4

  • Molecular Formula : C22H14O4

  • Molecular Weight : 342.34

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Drug Reference Standards & Impurity Synthesis in India
PA 01 22020

Adapalene - Impurity B

6-[3-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)-4- (methyloxy)phenyl]naphthalene-2-carboxylic acid

  • Catalogue No.:PA 01 22020

  • CAS :

    1346599-76-5

  • Molecular Formula : C28H28O4

  • Molecular Weight : 428.53

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Drug Reference Standards & Impurity Synthesis in India
PA 01 22030

Adapalene - Impurity C

1-(2-Methoxyphenyl)tricyclo[3.3.1.13,7]decane

  • Catalogue No.:PA 01 22030

  • CAS :

    43109-77-9

  • Molecular Formula : C17H22O

  • Molecular Weight : 242.36

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Drug Reference Standards & Impurity Synthesis in India
PA 01 22040

Adapalene - Impurity D

1,1'-[4,4'-Bis(Methoxy)biphenyl-3,3'-diyl]bis(tricyclo[3.3.1.13,7]decane)

  • Catalogue No.:PA 01 22040

  • CAS :

    932033-57-3

  • Molecular Formula : C34H42O2

  • Molecular Weight : 482.7

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Drug Reference Standards & Impurity Synthesis in India
PA 01 22510

Methyl 6-Bromo-2-napthoate

Methyl 6-Bromo-2-napthoate

  • Catalogue No.:PA 01 22510

  • CAS :

    33626-98-1

  • Molecular Formula : C12H9BrO2

  • Molecular Weight : 265.1

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Drug Reference Standards & Impurity Synthesis in India
PA 01 22520

Adapalene Methyl Ester

Adapalene Methyl Ester

  • Catalogue No.:PA 01 22520

  • CAS :

    106685-41-0

  • Molecular Formula : C29H30O3

  • Molecular Weight : 426.55

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Drug Reference Standards & Impurity Synthesis in India
PA USP1011709

Adapalene (1011709)

Adapalene (1011709)

  • Catalogue No.:PA USP1011709

  • CAS :

    106685-40-9

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1011721

Adapalene Related Compound B (Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoate) (1011721)

Adapalene Related Compound B (Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoate) (1011721)

  • Catalogue No.:PA USP1011721

  • CAS :

    106685-41-0

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1011710

Adapalene Related Compound A (Methyl 6-bromo-2-naphthoate) (1011710)

Adapalene Related Compound A (Methyl 6-bromo-2-naphthoate) (1011710)

  • Catalogue No.:PA USP1011710

  • CAS :

    33626-98-1

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1011732

Adapalene Related Compound C (2-(adamant-1-yl)methoxybenzene) (1011732)

Adapalene Related Compound C (2-(adamant-1-yl)methoxybenzene) (1011732)

  • Catalogue No.:PA USP1011732

  • CAS :

    43109-77-9

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1011743

Adapalene Related Compound D (4,4'-dimethoxy-3,3'-di(adamant-1-yl)biphenyl) (1011743)

Adapalene Related Compound D (4,4'-dimethoxy-3,3'-di(adamant-1-yl)biphenyl) (1011743)

  • Catalogue No.:PA USP1011743

  • CAS :

    932033-57-3

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1011754

Adapalene Related Compound E (2,2'-binaphthyl-6,6'-dicarboxylic acid) (1011754)

Adapalene Related Compound E (2,2'-binaphthyl-6,6'-dicarboxylic acid) (1011754)

  • Catalogue No.:PA USP1011754

  • CAS :

    932033-58-4

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001121

Adapalene (Y0001121)

Adapalene (Y0001121)

  • Catalogue No.:PA EPY0001121

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA BP1120RB

adapalene (1120RB)

adapalene (1120RB)

  • Catalogue No.:PA BP1120RB

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA BP1121RB

adapalene impurity standard (1121RB)

adapalene impurity standard (1121RB)

  • Catalogue No.:PA BP1121RB

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001120

Adapalene impurity C (Y0001120)

Adapalene impurity C (Y0001120)

  • Catalogue No.:PA EPY0001120

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001119

Adapalene for peak identification (Y0001119)

Adapalene for peak identification (Y0001119)

  • Catalogue No.:PA EPY0001119

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 01 22530

2-(1-Adamantyl)-4-bromoanisole

2-(1-Adamantyl)-4-bromoanisole

  • Catalogue No.:PA 01 22530

  • CAS :

    104224-63-7

  • Molecular Formula : C17H21BrO

  • Molecular Weight : 321.25

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Drug Reference Standards & Impurity Synthesis in India
PAI 01 018010

Dimethyl [2,2'-binaphthalene]-6,6'-dicarboxylate

Dimethyl [2,2'-binaphthalene]-6,6'-dicarboxylate

  • Catalogue No.:PAI 01 018010

  • CAS :

    161912-38-5

  • Molecular Formula : C24H18O4

  • Molecular Weight : 370.4

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221000

6-Bromo-2-naphthalenemethanol

6-Bromo-2-naphthalenemethanol

  • Catalogue No.:PA 01 0221000

  • CAS :

    100751-63-1

  • Molecular Formula : C11H9BrO

  • Molecular Weight : 237.10

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221001

6-(4-Methoxyphenyl)-2-naphthoic Acid

6-(4-Methoxyphenyl)-2-naphthoic Acid

  • Catalogue No.:PA 01 0221001

  • CAS :

    132292-17-2

  • Molecular Formula : C18H14O3

  • Molecular Weight : 278.31

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221002

6-(3-((3r,5r,7r)-Adamantan-1-yl)-4-methoxyphenyl)-1,4-dioxo-1,4-dihydronaphthalene-2-carboxylic Acid

6-(3-((3r,5r,7r)-Adamantan-1-yl)-4-methoxyphenyl)-1,4-dioxo-1,4-dihydronaphthalene-2-carboxylic Acid

  • Catalogue No.:PA 01 0221002

  • CAS :

    NA

  • Molecular Formula : C28H26O5

  • Molecular Weight : 442.51

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221003

3'-((3r,5r,7r)-Adamantan-1-yl)-4'-methoxy-3-((E)-3-oxoprop-1-en-1-yl)-[1,1'-biphenyl]-4-carbaldehyde

3'-((3r,5r,7r)-Adamantan-1-yl)-4'-methoxy-3-((E)-3-oxoprop-1-en-1-yl)-[1,1'-biphenyl]-4-carbaldehyde

  • Catalogue No.:PA 01 0221003

  • CAS :

    NA

  • Molecular Formula : C27H28O3

  • Molecular Weight : 400.52

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221004

2-(Adamantan-1-yl)-4-bromophenol

2-(Adamantan-1-yl)-4-bromophenol

  • Catalogue No.:PA 01 0221004

  • CAS :

    104224-68-2

  • Molecular Formula : C16H19BrO

  • Molecular Weight : 307.23

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221005

Methyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate

Methyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate

  • Catalogue No.:PA 01 0221005

  • CAS :

    NA

  • Molecular Formula : C29H30O4

  • Molecular Weight : 442.56

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221006

O-Desmethyl adapalene

O-Desmethyl adapalene

  • Catalogue No.:PA 01 0221006

  • CAS :

    125316-60-1

  • Molecular Formula : C27H26O3

  • Molecular Weight : 398.5

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221007

Adapalene Acyl-Glucuronide

Adapalene Acyl-Glucuronide

  • Catalogue No.:PA 01 0221007

  • CAS :

    NA

  • Molecular Formula : C34H36O9

  • Molecular Weight : 588.65

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221008

3-Hydroxy Adapalene methyl ester

3-Hydroxy Adapalene methyl ester

  • Catalogue No.:PA 01 0221008

  • CAS :

    NA

  • Molecular Formula : C29H30O4

  • Molecular Weight : 442.56

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221009

O-Desmethyl Adapalene-13C6

O-Desmethyl Adapalene-13C6

  • Catalogue No.:PA 01 0221009

  • CAS :

    NA

  • Molecular Formula : C2113C6H26O3

  • Molecular Weight : 404.46

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Drug Reference Standards & Impurity Synthesis in India
PAI 01 018011

6-(3-(3-Bromoadamantan-1-yl)-4-methoxyphenyl)-2-naphthoic Acid

6-(3-(3-Bromoadamantan-1-yl)-4-methoxyphenyl)-2-naphthoic Acid

  • Catalogue No.:PAI 01 018011

  • CAS :

    NA

  • Molecular Formula : C28H27BrO3

  • Molecular Weight : 491.43

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221010

6-Bromo-2-naphthoic Acid

6-Bromo-2-naphthoic Acid

  • Catalogue No.:PA 01 0221010

  • CAS :

    5773-80-8

  • Molecular Formula : C11H7BrO2

  • Molecular Weight : 251.08

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221011

Adapalene Dimer Impurity

Adapalene Dimer Impurity

  • Catalogue No.:PA 01 0221011

  • CAS :

    NA

  • Molecular Formula : C46H40O6

  • Molecular Weight : 688.82

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Drug Reference Standards & Impurity Synthesis in India
PAI 01 018012

6-[(3-Adamantyl-4-Methoxyphenyl)]-2-Naphthoic Acid Ethyl Ester

6-[(3-Adamantyl-4-Methoxyphenyl)]-2-Naphthoic Acid Ethyl Ester

  • Catalogue No.:PAI 01 018012

  • CAS :

    951645-46-8

  • Molecular Formula : C30H32O3

  • Molecular Weight : 440.58

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Drug Reference Standards & Impurity Synthesis in India
PAI 01 018013

Ethyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate

Ethyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate

  • Catalogue No.:PAI 01 018013

  • CAS :

    NA

  • Molecular Formula : C30H32O4

  • Molecular Weight : 456.58

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221012

Methyl 6-(4-methoxyphenyl)-2-naphthoate

Methyl 6-(4-methoxyphenyl)-2-naphthoate

  • Catalogue No.:PA 01 0221012

  • CAS :

    128272-36-6

  • Molecular Formula : C19H16O3

  • Molecular Weight : 292.33

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221013

Methyl 6-(3-((3r,5r,7r)-adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoate

Methyl 6-(3-((3r,5r,7r)-adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoate

  • Catalogue No.:PA 01 0221013

  • CAS :

    106685-43-2

  • Molecular Formula : C28H28O3

  • Molecular Weight : 412.53

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221014

4-(6-Methoxynaphthalen-2-yl)benzoic Acid

4-(6-Methoxynaphthalen-2-yl)benzoic Acid

  • Catalogue No.:PA 01 0221014

  • CAS :

    107430-57-9

  • Molecular Formula : C18H14O3

  • Molecular Weight : 278.31

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Drug Reference Standards & Impurity Synthesis in India
PAI 01 018014

3-(5-Bromo-2-methoxyphenyl)adamantan-1-ol

3-(5-Bromo-2-methoxyphenyl)adamantan-1-ol

  • Catalogue No.:PAI 01 018014

  • CAS :

    NA

  • Molecular Formula : C17H21BrO2

  • Molecular Weight : 337.26

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Drug Reference Standards & Impurity Synthesis in India
PAI 01 018015

(3-(3-Hydroxyadamantan-1-yl)-4-methoxyphenyl)boronic Acid

(3-(3-Hydroxyadamantan-1-yl)-4-methoxyphenyl)boronic Acid

  • Catalogue No.:PAI 01 018015

  • CAS :

    NA

  • Molecular Formula : C17H23BO4

  • Molecular Weight : 302.18

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Drug Reference Standards & Impurity Synthesis in India
PAI 01 018016

3-(5-Bromo-2-hydroxyphenyl)adamantan-1-ol

3-(5-Bromo-2-hydroxyphenyl)adamantan-1-ol

  • Catalogue No.:PAI 01 018016

  • CAS :

    NA

  • Molecular Formula : C16H19BrO2

  • Molecular Weight : 323.23

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221015

1-(3-Bromo-2-methoxyphenyl)adamantane

1-(3-Bromo-2-methoxyphenyl)adamantane

  • Catalogue No.:PA 01 0221015

  • CAS :

    NA

  • Molecular Formula : C17H21BrO

  • Molecular Weight : 321.26

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Drug Reference Standards & Impurity Synthesis in India
PA 01 0221016

1,3-Bis(5-bromo-2-methoxyphenyl)adamantane

1,3-Bis(5-bromo-2-methoxyphenyl)adamantane

  • Catalogue No.:PA 01 0221016

  • CAS :

    932033-56-2

  • Molecular Formula : C24H26Br2O2

  • Molecular Weight : 506.28

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