adapalene and its Impurities
Adapalene is marketed by Galderma under the trade names Differin and Adaferin. It is a member of the retinoid drug class that is typically found in topical formulations used for the treatment of acne. It may be used to treat keratosis pilaris as well as other skin conditions as off-label use. Reference standards of Adapalene API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


Adapalene Related Compound B (Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoate) (1011721)
Adapalene Related Compound B (Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoate) (1011721)
Catalogue No.:PA USP1011721
CAS :
106685-41-0
Molecular Formula : NA
Molecular Weight : NA


6-(3-((3r,5r,7r)-Adamantan-1-yl)-4-methoxyphenyl)-1,4-dioxo-1,4-dihydronaphthalene-2-carboxylic Acid
6-(3-((3r,5r,7r)-Adamantan-1-yl)-4-methoxyphenyl)-1,4-dioxo-1,4-dihydronaphthalene-2-carboxylic Acid
Catalogue No.:PA 01 0221002
CAS :
NA
Molecular Formula : C28H26O5
Molecular Weight : 442.51


3'-((3r,5r,7r)-Adamantan-1-yl)-4'-methoxy-3-((E)-3-oxoprop-1-en-1-yl)-[1,1'-biphenyl]-4-carbaldehyde
3'-((3r,5r,7r)-Adamantan-1-yl)-4'-methoxy-3-((E)-3-oxoprop-1-en-1-yl)-[1,1'-biphenyl]-4-carbaldehyde
Catalogue No.:PA 01 0221003
CAS :
NA
Molecular Formula : C27H28O3
Molecular Weight : 400.52