alectinib and its Impurities
Alectinib is used to treat a certain type of lung cancer. It is an oral drug that blocks the activity of anaplastic lymphoma kinase. Reference standards of Alectinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic Acid
6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic Acid
Catalogue No.:PA 01 2981002
CAS :
1256584-78-7
Molecular Formula : C30H36N4O3
Molecular Weight : 500.64
tert-Butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate Hydrochloride
tert-Butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate Hydrochloride
Catalogue No.:PA 01 2981004
CAS :
1256584-77-6
Molecular Formula : C34H45ClN4O3
Molecular Weight : 593.21
9-Ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-5-nitroso-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
9-Ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-5-nitroso-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Catalogue No.:PA 01 2981005
CAS :
NA
Molecular Formula : C30H33N5O3
Molecular Weight : 511.63
9-Ethyl-6,6-dimethyl-10-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
9-Ethyl-6,6-dimethyl-10-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Catalogue No.:PA 01 2981006
CAS :
1256584-79-8
Molecular Formula : C30H34N4O2
Molecular Weight : 482.63
9-Ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carboxamide
9-Ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carboxamide
Catalogue No.:PA 01 2981008
CAS :
NA
Molecular Formula : C30H36N4O3
Molecular Weight : 500.64
2-(2-(6-Cyano-1-nitroso-1H-indol-2-yl)propan-2-yl)-5-ethyl-4-(4-morpholinopiperidin-1-yl)benzoic Acid
2-(2-(6-Cyano-1-nitroso-1H-indol-2-yl)propan-2-yl)-5-ethyl-4-(4-morpholinopiperidin-1-yl)benzoic Acid
Catalogue No.:PA 01 2981009
CAS :
NA
Molecular Formula : C30H35N5O4
Molecular Weight : 529.64
tert-Butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1-nitroso-1H-indole-3-carboxylate
tert-Butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1-nitroso-1H-indole-3-carboxylate
Catalogue No.:PA 01 2981012
CAS :
NA
Molecular Formula : C34H43N5O4
Molecular Weight : 585.75
3-Cyano-9-ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-2-sulfonic Acid
3-Cyano-9-ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-2-sulfonic Acid
Catalogue No.:PA 01 2981013
CAS :
2412921-45-8
Molecular Formula : C30H34N4O5S
Molecular Weight : 562.69
8-(4-(4-(3-Cyano-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl)piperazin-1-yl)piperidin-1-yl)-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
8-(4-(4-(3-Cyano-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl)piperazin-1-yl)piperidin-1-yl)-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Catalogue No.:PA 01 2981014
CAS :
NA
Molecular Formula : C51H51N7O2
Molecular Weight : 793.41
N-(1-(3-Cyano-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl)piperidin-4-yl)-N-(2-ethoxyethyl)nitrous amide
N-(1-(3-Cyano-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl)piperidin-4-yl)-N-(2-ethoxyethyl)nitrous amide
Catalogue No.:PA 01 2981015
CAS :
NA
Molecular Formula : C30H35N5O3
Molecular Weight : 513.64
