Alprazolam and its Impurities
Alprazolam is mostly used in short term management of anxiety disorders, panic disorders, and nausea due to chemotherapy. It is sold under the trade name Xanax, among others, is a short-acting benzodiazepine. Reference standards of Alprazolam API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(2-(3-(Aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl)-5-chlorophenyl)(phenyl)methanone methanesulfonate
(2-(3-(Aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl)-5-chlorophenyl)(phenyl)methanone methanesulfonate
Catalogue No.:PA 01 0401000
CAS :
NA
Molecular Formula : C18H19ClN4O4S
Molecular Weight : 422.88
Alprazolam - Impurity I
[5-Chloro-2-[3-[[(6RS)-8-chloro-6-hydroxy-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4, 3-a][1,4]benzodiazepin-5(6H)-yl]methyl]-5-methyl-4H-1,2,4-triazol-4- yl]phenyl]phenylmethanone
Catalogue No.:PA 01 40090
CAS :
NA
Molecular Formula : C34H27Cl2N7O2
Molecular Weight : 636.54
Alprazolam - Impurity J
7,11-Dichloro-3,15-dimethyl-8b,9a-diphenyl-8b,19a-dihydro-9aH,18H-benzo[5',6'][1,2,4]triazolo[3'',4'':3',4'][1,4]diazepino[7',1':2,3]oxazolo[4,5-c][1,2,4]triazolo[4,3-a]quinoline
Catalogue No.:PA 01 40100
CAS :
NA
Molecular Formula : C34H25Cl2N7O
Molecular Weight : 618.52
