amlodipine besilate and its Impurities
Amlodipine Besilate is commonly used in the treatment of high blood pressure and angina._x000D_ It is initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Reference standards of Amlodipine Besilate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


Amlodipine Besilate - Impurity A
3-Ethyl 5-methyl (4RS)-4-(2-chlorophenyl)-2-[[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Catalogue No.:PA 01 50010
CAS :
88150-62-3
Molecular Formula : C28H27ClN2O7
Molecular Weight : 538.98


3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
Catalogue No.:PAI 01 052003
CAS :
NA
Molecular Formula : C32H33ClN2O9S2
Molecular Weight : 689.19


3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-formyl-4-methyl-2-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-formyl-4-methyl-2-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
Catalogue No.:PAI 01 052004
CAS :
NA
Molecular Formula : C33H33ClN2O10S2
Molecular Weight : 717.2


5-Ethyl 3-methyl 2-(bromomethyl)-4-(2-chlorophenyl)-6-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
5-Ethyl 3-methyl 2-(bromomethyl)-4-(2-chlorophenyl)-6-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
Catalogue No.:PAI 01 052005
CAS :
NA
Molecular Formula : C32H32BrClN2O9S2
Molecular Weight : 768.09


5-Ethyl 3-methyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
5-Ethyl 3-methyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-((2-(phenylsulfonamido)ethoxy)methyl)-1-(phenylsulfonyl)-1,4-dihydropyridine-3,5-dicarboxylate
Catalogue No.:PAI 01 052006
CAS :
NA
Molecular Formula : C42H40ClN3O12S2
Molecular Weight : 878.36