amlodipine and its Impurities

Amlodipine is commonly used in the treatment of high blood pressure and angina. Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Reference standards of Amlodipine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 64 results for amlodipine Impurities
PA 01 49000

Amlodipine - API

Amlodipine


  • Catalogue No.:PA 01 49000

  • CAS :

    88150-42-9

  • Molecular Formula : C20H25ClN2O5

  • Molecular Weight : 408.88

PA 01 49520

Amlodipine Azido Impurity

Amlodipine Azido Impurity


  • Catalogue No.:PA 01 49520

  • CAS :

    88150-46-3

  • Molecular Formula : C20H23ClN4O5

  • Molecular Weight : 434.87

PA 01 49530

Amlodipine 4-chloro Isomer

Amlodipine 4-chloro Isomer


  • Catalogue No.:PA 01 49530

  • CAS :

    NA

  • Molecular Formula : C20H25ClN2O5

  • Molecular Weight : 408.88

PA 01 49540

(R)-Amlodipine

(R)-Amlodipine


  • Catalogue No.:PA 01 49540

  • CAS :

    103129-81-3

  • Molecular Formula : C20H25ClN2O5

  • Molecular Weight : 408.88

PA 01 49550

2-((2-Aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid

2-((2-Aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid


  • Catalogue No.:PA 01 49550

  • CAS :

    1821498-25-2

  • Molecular Formula : C17H19ClN2O5

  • Molecular Weight : 366.8

PA 01 49560

Amlodipine N-Galactopyranoside

Amlodipine N-Galactopyranoside


  • Catalogue No.:PA 01 49560

  • CAS :

    NA

  • Molecular Formula : C26H35ClN2O10

  • Molecular Weight : 571.02

PA 01 49570

Amlodipine Mannitol Adduct

Amlodipine Mannitol Adduct


  • Catalogue No.:PA 01 49570

  • CAS :

    NA

  • Molecular Formula : C26H37ClN2O10

  • Molecular Weight : 573.03

PA 01 49580

(S)-Amlodipine

(S)-Amlodipine


  • Catalogue No.:PA 01 49580

  • CAS :

    103129-82-4

  • Molecular Formula : C20H25ClN2O5

  • Molecular Weight : 408.88

PA 01 49590

4-(2-Chlorophenyl)-1,4-dihydro-2-(hydroxymethyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester

4-(2-Chlorophenyl)-1,4-dihydro-2-(hydroxymethyl)-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester


  • Catalogue No.:PA 01 49590

  • CAS :

    79781-21-8

  • Molecular Formula : C18H20ClNO5

  • Molecular Weight : 365.81

PA 01 49600

3-Ethyl 5-Methyl 2-((2-acetamidoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3-Ethyl 5-Methyl 2-((2-acetamidoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PA 01 49600

  • CAS :

    93848-82-9

  • Molecular Formula : C22H27ClN2O6

  • Molecular Weight : 450.91

PA 01 49610

3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-((2-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)amino)ethoxy)methyl)-1,4-dihydropyridine-3,5-dicarboxylate

3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-((2-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)amino)ethoxy)methyl)-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PA 01 49610

  • CAS :

    NA

  • Molecular Formula : C26H35ClN2O10

  • Molecular Weight : 571.02

PA STI 007410

(R)-Amlodipine-d4


  • Catalogue No.:PA STI 007410

  • CAS :

    1346616-97-4

  • Molecular Formula : C20H21D4ClN2O5

  • Molecular Weight : 412.90

PA STI 007420

(S)-Amlodipine-d4


  • Catalogue No.:PA STI 007420

  • CAS :

    1346616-97-4

  • Molecular Formula : C20H21D4ClN2O5

  • Molecular Weight : 412.90

PA STI 007430

Amlodipine-d4


  • Catalogue No.:PA STI 007430

  • CAS :

    1185246-14-3

  • Molecular Formula : C20H21D4ClN2O5

  • Molecular Weight : 412.90

PA STI 007440

Amlodipine-d4 Maleic Acid Salt


  • Catalogue No.:PA STI 007440

  • CAS :

    1185246-15-4

  • Molecular Formula : C24H25D4ClN2O9

  • Molecular Weight : 528.97

PA USP1029556

Amlodipine Related Compound E (Diethyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-di (1029556)


  • Catalogue No.:PA USP1029556

  • CAS :

    140171-65-9

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1029567

Amlodipine Related Compound F (Dimethyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-d (1029567)


  • Catalogue No.:PA USP1029567

  • CAS :

    140171-66-0

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1029545

Amlodipine Related Compound D (3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-{[2-(1,3-dioxoisoindolin-2-yl) (1029545)


  • Catalogue No.:PA USP1029545

  • CAS :

    88150-62-3

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1029614

Amlodipine Related Compound K (Ethyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-benzo[b][1,4 (1029614)


  • Catalogue No.:PA USP1029614

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1029501

Amlodipine Besylate (1029501)


  • Catalogue No.:PA USP1029501

  • CAS :

    111470-99-6

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1029512

Amlodipine Related Compound A (3-Ethyl, 5-methyl [2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-meth (1029512)


  • Catalogue No.:PA USP1029512

  • CAS :

    113994-41-5

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1029534

Amlodipine Related Compound C (Dimethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dic (1029534)


  • Catalogue No.:PA USP1029534

  • CAS :

    43067-01-2

  • Molecular Formula :

  • Molecular Weight : NA

PA USP1029523

Amlodipine Related Compound B (3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-({2-[2-(methylcarbamo (1029523)


  • Catalogue No.:PA USP1029523

  • CAS :

    721958-72-1

  • Molecular Formula :

  • Molecular Weight : NA

PA EPY0000049

Amlodipine besilate (Y0000049)


  • Catalogue No.:PA EPY0000049

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA EPY0001068

Amlodipine impurity A (Y0001068)


  • Catalogue No.:PA EPY0001068

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA EPY0001069

Amlodipine impurity B (Y0001069)


  • Catalogue No.:PA EPY0001069

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA EPY0001070

Amlodipine impurity G (Y0001070)


  • Catalogue No.:PA EPY0001070

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA EPY0001067

Amlodipine for peak identification (Y0001067)


  • Catalogue No.:PA EPY0001067

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA JP0009

Amlodipine Besilate (JP 0009)


  • Catalogue No.:PA JP0009

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PAI 01 003010

3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate

3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003010

  • CAS :

    NA

  • Molecular Formula : C20H23ClN2O5

  • Molecular Weight : 406.90

PAI 01 003020

2-((Z)-tert-Butyl 2-(2-chlorobenzylidene)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

2-((Z)-tert-Butyl 2-(2-chlorobenzylidene)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate


  • Catalogue No.:PAI 01 003020

  • CAS :

    NA

  • Molecular Formula : C23H20ClNO6

  • Molecular Weight : 441.90

PAI 01 003030

(E)-tert-Butyl 3-aminobut-2-enoate

(E)-tert-Butyl 3-aminobut-2-enoate


  • Catalogue No.:PAI 01 003030

  • CAS :

    NA

  • Molecular Formula : C17H20O4

  • Molecular Weight : 157.20

PAI 01 003040

3-tert-Butyl 5-ethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3-tert-Butyl 5-ethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003040

  • CAS :

    NA

  • Molecular Formula : C13H16O2

  • Molecular Weight : 581.10

PAI 01 003050

3-tert-Butyl 5-ethyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3-tert-Butyl 5-ethyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003050

  • CAS :

    NA

  • Molecular Formula : C23H31ClN2O5

  • Molecular Weight : 451.00

PAI 01 003060

(Z)-Benzyl 3-aminobut-2-enoate

(Z)-Benzyl 3-aminobut-2-enoate


  • Catalogue No.:PAI 01 003060

  • CAS :

    464917-79-1

  • Molecular Formula : C11H13NO2

  • Molecular Weight : 191.20

PAI 01 003070

3-Benzyl 5-ethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3-Benzyl 5-ethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003070

  • CAS :

    NA

  • Molecular Formula : C34H31ClN2O7

  • Molecular Weight : 615.07

PAI 01 003080

3-Benzyl 5-ethyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3-Benzyl 5-ethyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003080

  • CAS :

    NA

  • Molecular Formula : C26H29ClN2O5

  • Molecular Weight : 484.97

PAI 01 003090

(Z)-Ethyl 3-aminobut-2-enoate

(Z)-Ethyl 3-aminobut-2-enoate


  • Catalogue No.:PAI 01 003090

  • CAS :

    NA

  • Molecular Formula : C6H11NO2

  • Molecular Weight : 129.20

PAI 01 003100

Diethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Diethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003100

  • CAS :

    NA

  • Molecular Formula : C29H29ClN2O7

  • Molecular Weight : 553.00

PAI 01 003110

Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate


  • Catalogue No.:PAI 01 003110

  • CAS :

    NA

  • Molecular Formula : C16H17NO6

  • Molecular Weight : 319.30

PAI 01 003120

(Z)-Ethyl 2-(2-chlorobenzylidene)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

(Z)-Ethyl 2-(2-chlorobenzylidene)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate


  • Catalogue No.:PAI 01 003120

  • CAS :

    NA

  • Molecular Formula : C23H20ClNO6

  • Molecular Weight : 441.90

PAI 01 003130

4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Methyl Ester

4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Methyl Ester


  • Catalogue No.:PAI 01 003130

  • CAS :

    111429-90-4

  • Molecular Formula : C15H15NO6

  • Molecular Weight : 305.28

PAI 01 003140

(EZ)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Methyl Ester

(EZ)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Methyl Ester


  • Catalogue No.:PAI 01 003140

  • CAS :

    N/A

  • Molecular Formula : C22H18ClNO6

  • Molecular Weight : 427.83

PAI 01 003150

4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester

4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester


  • Catalogue No.:PAI 01 003150

  • CAS :

    140171-50-2

  • Molecular Formula : C27H25ClN2O7

  • Molecular Weight : 524.95

PAI 01 003160

3-Ethyl 5-methyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

3-Ethyl 5-methyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003160

  • CAS :

    NA

  • Molecular Formula : C18H20ClNO4

  • Molecular Weight : 349.81

PAI 01 003170

N-Boc-ethanolamine

N-Boc-ethanolamine


  • Catalogue No.:PAI 01 003170

  • CAS :

    26690-80-2

  • Molecular Formula : C7H15NO3

  • Molecular Weight : 161.20

PAI 01 003180

3-Ethyl 5-methyl 2-((2-((tert-butoxycarbonyl)amino)ethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3-Ethyl 5-methyl 2-((2-((tert-butoxycarbonyl)amino)ethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003180

  • CAS :

    NA

  • Molecular Formula : C25H33ClN2O7

  • Molecular Weight : 509.00

PAI 01 003190

Ethyl (Z)-2-(2-chlorobenzylidene)-3-oxobutanoate

Ethyl (Z)-2-(2-chlorobenzylidene)-3-oxobutanoate


  • Catalogue No.:PAI 01 003190

  • CAS :

    NA

  • Molecular Formula : C13H13ClO3

  • Molecular Weight : 252.69

PAI 01 003200

3-Ethyl 5-methyl 1-benzyl-4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

3-Ethyl 5-methyl 1-benzyl-4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003200

  • CAS :

    NA

  • Molecular Formula : C25H26ClNO4

  • Molecular Weight : 439.94

PAI 01 003210

4-(2-Phthalimidoethoxy)acetoacetic Acid Ethyl Ester

4-(2-Phthalimidoethoxy)acetoacetic Acid Ethyl Ester


  • Catalogue No.:PAI 01 003210

  • CAS :

    88150-75-8

  • Molecular Formula : C16H17NO6

  • Molecular Weight : 319.31

PAI 01 003220

Ethyl (E)-2-(2-chlorobenzylidene)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

Ethyl (E)-2-(2-chlorobenzylidene)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate


  • Catalogue No.:PAI 01 003220

  • CAS :

    NA

  • Molecular Formula : C23H20ClNO6

  • Molecular Weight : 441.86

PAI 01 003230

2-Azidoethanol

2-Azidoethanol


  • Catalogue No.:PAI 01 003230

  • CAS :

    1517-05-1

  • Molecular Formula : C2H5N3O

  • Molecular Weight : 87.08

PAI 01 003240

Ethyl (2-Azidoethoxy)acetoacetate

Ethyl (2-Azidoethoxy)acetoacetate


  • Catalogue No.:PAI 01 003240

  • CAS :

    88150-45-2

  • Molecular Formula : C8H13N3O4

  • Molecular Weight : 215.21

PA 01 49620

Ethyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-benzo[b][1,4]oxazine-5-carboxylate

Ethyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-benzo[b][1,4]oxazine-5-carboxylate


  • Catalogue No.:PA 01 49620

  • CAS :

    1621516-91-3

  • Molecular Formula : C18H20ClNO3

  • Molecular Weight : 333.81

PA IPIPRS 01 11

S(-)Amlodipine Besylate (IPRS/01/11)


  • Catalogue No.:PA IPIPRS 01 11

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA IPIPRS 66 14

Amlodipine Besylate (IPRS/66/14)


  • Catalogue No.:PA IPIPRS 66 14

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PAI 01 003250

2-Hydroxyethyl Benzenesulfonate


  • Catalogue No.:PAI 01 003250

  • CAS :

    249285-50-5

  • Molecular Formula : C8H10O4S

  • Molecular Weight : 202.22

PAI 01 003260

2-Hydroxyethyl 4-methylbenzenesulfonate


  • Catalogue No.:PAI 01 003260

  • CAS :

    42772-85-0

  • Molecular Formula : C9H12O4S

  • Molecular Weight : 216.25

PAI 01 003270

3-Ethyl 5-methyl 2-(chloromethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003270

  • CAS :

    NA

  • Molecular Formula : C18H19Cl2NO4

  • Molecular Weight : 384.25

PAI 01 003280

2-Bromoethanol


  • Catalogue No.:PAI 01 003280

  • CAS :

    540-51-2

  • Molecular Formula : C2H5BrO

  • Molecular Weight : 124.97

PAI 01 003290

Ethyl (Z)-4-chloro-2-(2-chlorobenzylidene)-3-oxobutanoate


  • Catalogue No.:PAI 01 003290

  • CAS :

    NA

  • Molecular Formula : C13H12Cl2O3

  • Molecular Weight : 287.14

PAI 01 003300

3-Ethyl 5-methyl 2-((2-bromoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PAI 01 003300

  • CAS :

    NA

  • Molecular Formula : C20H23BrClNO5

  • Molecular Weight : 472.76

PA 01 49630

Diethyl 4-(2-chlorophenyl)-2-((2-(2-((2-((4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl)methoxy)ethyl)carbamoyl)benzamido)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Diethyl 4-(2-chlorophenyl)-2-((2-(2-((2-((4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl)methoxy)ethyl)carbamoyl)benzamido)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate


  • Catalogue No.:PA 01 49630

  • CAS :

    NA

  • Molecular Formula : C49H54Cl2N4O12

  • Molecular Weight : 961.89

PA STI 088304

(±)-Amlodipine-d4 Maleate (2-chlorophenyl-d4)

(±)-Amlodipine-d4 Maleate (2-chlorophenyl-d4)


  • Catalogue No.:PA STI 088304

  • CAS :

    NA

  • Molecular Formula : C24H25D4ClN2O9

  • Molecular Weight : 528.98