Anisindione and its Impurities

Anisindione (brand name Miradon) is a synthetic anticoagulant and an indanedione derivative. it is indicated for the prophylaxis and treatment of venous thrombosis and its extension, the treatment of atrial fibrillation with embolization, the prophylaxis and treatment of pulmonary embolism, and as an adjunct in the treatment of coronary occlusion. Reference standards of Anisindione API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.