Apalutamide-impurities | Pharmaffiliates

Apalutamide and its Impurities

Apalutamide, sold under the brand name Erleada among others, is a nonsteroidal antiandrogen medication which is used in the treatment of prostate cancer. It is specifically indicated for use in conjunction with castration in the treatment of non-metastatic castration-resistant prostate cancer Reference standards of Apalutamide API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 24 results for Apalutamide Impurities
PA 01 2920000

Apalutamide - API

Apalutamide


  • Catalogue No.:PA 01 2920000

  • CAS :

    956104-40-8

  • Molecular Formula : C21H15F4N5O2S

  • Molecular Weight : 477.44

PA 01 2921000

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide


  • Catalogue No.:PA 01 2921000

  • CAS :

    1332391-11-3

  • Molecular Formula : C20H13F4N5O2S

  • Molecular Weight : 463.41

PA 01 2921001

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide


  • Catalogue No.:PA 01 2921001

  • CAS :

    1332391-92-0

  • Molecular Formula : C21H15F4N5O3

  • Molecular Weight : 461.38

PA 01 2921002

5-(5-(3-Fluoro-4-(methylcarbamoyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)picolinamide

5-(5-(3-Fluoro-4-(methylcarbamoyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)picolinamide


  • Catalogue No.:PA 01 2921002

  • CAS :

    NA

  • Molecular Formula : C21H17F4N5O3S

  • Molecular Weight : 495.45

PA 01 2921003

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dithioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide;

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dithioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide;


  • Catalogue No.:PA 01 2921003

  • CAS :

    2649802-40-2

  • Molecular Formula : C21H15F4N5OS2

  • Molecular Weight : 493.5

PA 01 2921004

4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide

4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide


  • Catalogue No.:PA 01 2921004

  • CAS :

    915087-26-2

  • Molecular Formula : C13H14FN3O

  • Molecular Weight : 247.27

PA 01 2921005

4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide

4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide


  • Catalogue No.:PA 01 2921005

  • CAS :

    1950587-20-8

  • Molecular Formula : C20H17F4N5O2

  • Molecular Weight : 435.38

PA 01 2921006

1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid

1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid


  • Catalogue No.:PA 01 2921006

  • CAS :

    2227589-22-0

  • Molecular Formula : C13H15FN2O3

  • Molecular Weight : 266.27

PA 01 2921007

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea


  • Catalogue No.:PA 01 2921007

  • CAS :

    2422147-84-8

  • Molecular Formula : C8H5F3N4S

  • Molecular Weight : 246.21

PA 01 2921008

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid


  • Catalogue No.:PA 01 2921008

  • CAS :

    1332391-04-4

  • Molecular Formula : C20H12F4N4O3S

  • Molecular Weight : 464.39

PA STI 088917

Apalutamide D3

Apalutamide D3


  • Catalogue No.:PA STI 088917

  • CAS :

    1638885-61-6

  • Molecular Formula : C21H12D3F4N5O2S

  • Molecular Weight : 480.46

PA STI 088918

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide


  • Catalogue No.:PA STI 088918

  • CAS :

    NA

  • Molecular Formula : C2013CH12D3F4N5O2S

  • Molecular Weight : 481.45

PA 01 2921009

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide


  • Catalogue No.:PA 01 2921009

  • CAS :

    1332389-57-7

  • Molecular Formula : C21H16F3N5O2S

  • Molecular Weight : 459.45

PA 01 2921010

2-Fluoro-4-(hydroxyamino)-N-methylbenzamide

2-Fluoro-4-(hydroxyamino)-N-methylbenzamide


  • Catalogue No.:PA 01 2921010

  • CAS :

    NA

  • Molecular Formula : C8H9FN2O2

  • Molecular Weight : 184.17

PA 01 2921011

5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile

5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile


  • Catalogue No.:PA 01 2921011

  • CAS :

    573762-62-6

  • Molecular Formula : C7H4F3N3

  • Molecular Weight : 187.13

PA 01 2921012

2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine

2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine


  • Catalogue No.:PA 01 2921012

  • CAS :

    956104-42-0

  • Molecular Formula : C6H2BrF3N2O2

  • Molecular Weight : 270.99

PA 01 2921013

4-Amino-N-methylbenzamide

4-Amino-N-methylbenzamide


  • Catalogue No.:PA 01 2921013

  • CAS :

    6274-22-2

  • Molecular Formula : C8H10N2O

  • Molecular Weight : 150.18

PA 01 2921014

2-Fluoro-4-nitrotoluene

2-Fluoro-4-nitrotoluene


  • Catalogue No.:PA 01 2921014

  • CAS :

    1427-07-2

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

PA 01 2921015

4-Amino-2-fluorobenzoic Acid

4-Amino-2-fluorobenzoic Acid


  • Catalogue No.:PA 01 2921015

  • CAS :

    446-31-1

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

PA 01 2921017

O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate

O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate


  • Catalogue No.:PA 01 2921017

  • CAS :

    NA

  • Molecular Formula : C28H19F4N5O3S2

  • Molecular Weight : 613.61

PA 01 2921016

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide


  • Catalogue No.:PA 01 2921016

  • CAS :

    NA

  • Molecular Formula : C40H27F8N9O4S

  • Molecular Weight : 881.76

PA 01 2921018

1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)Cyclobutane-1-Carboxylic Acid, Potassium Salt (1:1)

1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylic acid, potassium salt (1:1)


  • Catalogue No.:PA 01 2921018

  • CAS :

    2408380-71-0

  • Molecular Formula : C13H14FKN2O3

  • Molecular Weight : 304.36

PA 01 2921019

Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate


  • Catalogue No.:PA 01 2921019

  • CAS :

    NA

  • Molecular Formula : C20H11F4N4NaO3S

  • Molecular Weight : 486.38

PA 01 2921020

Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate


  • Catalogue No.:PA 01 2921020

  • CAS :

    1950587-19-5

  • Molecular Formula : C21H14F4N4O3S

  • Molecular Weight : 478.42