Apalutamide and its Impurities

Apalutamide, sold under the brand name Erleada among others, is a nonsteroidal antiandrogen medication which is used in the treatment of prostate cancer. It is specifically indicated for use in conjunction with castration in the treatment of non-metastatic castration-resistant prostate cancer Reference standards of Apalutamide API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 36 results for Apalutamide Impurities
PA 01 2920000

Apalutamide

Apalutamide

  • Catalogue No.:PA 01 2920000

  • CAS :

    956104-40-8

  • Molecular Formula : C21H15F4N5O2S

  • Molecular Weight : 477.44

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PA 01 2921000

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide

  • Catalogue No.:PA 01 2921000

  • CAS :

    1332391-11-3

  • Molecular Formula : C20H13F4N5O2S

  • Molecular Weight : 463.41

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PA 01 2921001

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide

  • Catalogue No.:PA 01 2921001

  • CAS :

    1332391-92-0

  • Molecular Formula : C21H15F4N5O3

  • Molecular Weight : 461.38

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PA 01 2921002

5-(5-(3-Fluoro-4-(methylcarbamoyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)picolinamide

5-(5-(3-Fluoro-4-(methylcarbamoyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)picolinamide

  • Catalogue No.:PA 01 2921002

  • CAS :

    NA

  • Molecular Formula : C21H17F4N5O3S

  • Molecular Weight : 495.45

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PA 01 2921003

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dithioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-6,8-dithioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide

  • Catalogue No.:PA 01 2921003

  • CAS :

    2649802-40-2

  • Molecular Formula : C21H15F4N5OS2

  • Molecular Weight : 493.5

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PA 01 2921004

4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide

4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide

  • Catalogue No.:PA 01 2921004

  • CAS :

    915087-26-2

  • Molecular Formula : C13H14FN3O

  • Molecular Weight : 247.27

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PA 01 2921005

4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide

4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide

  • Catalogue No.:PA 01 2921005

  • CAS :

    1950587-20-8

  • Molecular Formula : C20H17F4N5O2

  • Molecular Weight : 435.38

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PA 01 2921006

1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid

1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid

  • Catalogue No.:PA 01 2921006

  • CAS :

    2227589-22-0

  • Molecular Formula : C13H15FN2O3

  • Molecular Weight : 266.27

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PA 01 2921007

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea

  • Catalogue No.:PA 01 2921007

  • CAS :

    2422147-84-8

  • Molecular Formula : C8H5F3N4S

  • Molecular Weight : 246.21

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PA 01 2921008

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid

  • Catalogue No.:PA 01 2921008

  • CAS :

    1332391-04-4

  • Molecular Formula : C20H12F4N4O3S

  • Molecular Weight : 464.39

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PA STI 088917

Apalutamide D3

Apalutamide D3

  • Catalogue No.:PA STI 088917

  • CAS :

    1638885-61-6

  • Molecular Formula : C21H12D3F4N5O2S

  • Molecular Weight : 480.46

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PA STI 088918

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide

  • Catalogue No.:PA STI 088918

  • CAS :

    NA

  • Molecular Formula : C2013CH12D3F4N5O2S

  • Molecular Weight : 481.45

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PA 01 2921009

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide

  • Catalogue No.:PA 01 2921009

  • CAS :

    1332389-57-7

  • Molecular Formula : C21H16F3N5O2S

  • Molecular Weight : 459.45

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PA 01 2921010

2-Fluoro-4-(hydroxyamino)-N-methylbenzamide

2-Fluoro-4-(hydroxyamino)-N-methylbenzamide

  • Catalogue No.:PA 01 2921010

  • CAS :

    NA

  • Molecular Formula : C8H9FN2O2

  • Molecular Weight : 184.17

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PA 01 2921011

5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile

5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile

  • Catalogue No.:PA 01 2921011

  • CAS :

    573762-62-6

  • Molecular Formula : C7H4F3N3

  • Molecular Weight : 187.13

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PA 01 2921012

2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine

2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine

  • Catalogue No.:PA 01 2921012

  • CAS :

    956104-42-0

  • Molecular Formula : C6H2BrF3N2O2

  • Molecular Weight : 270.99

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PA 01 2921013

4-Amino-N-methylbenzamide

4-Amino-N-methylbenzamide

  • Catalogue No.:PA 01 2921013

  • CAS :

    6274-22-2

  • Molecular Formula : C8H10N2O

  • Molecular Weight : 150.18

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PA 01 2921014

2-Fluoro-4-nitrotoluene

2-Fluoro-4-nitrotoluene

  • Catalogue No.:PA 01 2921014

  • CAS :

    1427-07-2

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

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PA 01 2921015

4-Amino-2-fluorobenzoic Acid

4-Amino-2-fluorobenzoic Acid

  • Catalogue No.:PA 01 2921015

  • CAS :

    446-31-1

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

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PA 01 2921017

O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate

O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate

  • Catalogue No.:PA 01 2921017

  • CAS :

    NA

  • Molecular Formula : C28H19F4N5O3S2

  • Molecular Weight : 613.61

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PA 01 2921016

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide

  • Catalogue No.:PA 01 2921016

  • CAS :

    NA

  • Molecular Formula : C40H27F8N9O4S

  • Molecular Weight : 881.76

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PA 01 2921018

1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)Cyclobutane-1-Carboxylic Acid, Potassium Salt (1:1)

1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylic acid, potassium salt (1:1)

  • Catalogue No.:PA 01 2921018

  • CAS :

    2408380-71-0

  • Molecular Formula : C13H14FKN2O3

  • Molecular Weight : 304.36

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PA 01 2921019

Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

  • Catalogue No.:PA 01 2921019

  • CAS :

    NA

  • Molecular Formula : C20H11F4N4NaO3S

  • Molecular Weight : 486.38

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PA 01 2921020

Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

  • Catalogue No.:PA 01 2921020

  • CAS :

    1950587-19-5

  • Molecular Formula : C21H14F4N4O3S

  • Molecular Weight : 478.42

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PA 01 2921021

Ethyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

Ethyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

  • Catalogue No.:PA 01 2921021

  • CAS :

    1332388-83-6

  • Molecular Formula : C22H16F4N4O3S

  • Molecular Weight : 492.45

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PA 01 2921022

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)urea

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)urea

  • Catalogue No.:PA 01 2921022

  • CAS :

    NA

  • Molecular Formula : C8H5F3N4O

  • Molecular Weight : 230.15

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PA 01 2921023

4-((1-Cyanocyclobutyl)(nitroso)amino)-2-fluoro-N-methylbenzamide

4-((1-Cyanocyclobutyl)(nitroso)amino)-2-fluoro-N-methylbenzamide

  • Catalogue No.:PA 01 2921023

  • CAS :

    NA

  • Molecular Formula : C13H13FN4O2

  • Molecular Weight : 276.27

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PA 01 2921024

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)-N-methylbenzamide

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)-N-methylbenzamide

  • Catalogue No.:PA 01 2921024

  • CAS :

    2894796-76-8

  • Molecular Formula : C29H21F5N6O3S

  • Molecular Weight : 628.58

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PAI 01 292001

tert-Butyl (1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)carbamate

tert-Butyl (1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)carbamate

  • Catalogue No.:PAI 01 292001

  • CAS :

    1950587-16-2

  • Molecular Formula : C17H19F3N4O3

  • Molecular Weight : 384.36

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PAI 01 292002

Ethyl 1-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate

Ethyl 1-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate

  • Catalogue No.:PAI 01 292002

  • CAS :

    163554-54-9

  • Molecular Formula : C12H21NO4

  • Molecular Weight : 243.3

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PAI 01 292003

Ethyl 1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylate

Ethyl 1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylate

  • Catalogue No.:PAI 01 292003

  • CAS :

    2230023-67-1

  • Molecular Formula : C15H19FN2O3

  • Molecular Weight : 294.33

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PA STI 089835

Apalutamide D7

Apalutamide D7

  • Catalogue No.:PA STI 089835

  • CAS :

    NA

  • Molecular Formula : C21H8D7F4N5O2S

  • Molecular Weight : 484.48

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PA 01 2921025

N-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)nitrous amide

N-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)nitrous amide

  • Catalogue No.:PA 01 2921025

  • CAS :

    NA

  • Molecular Formula : C7H3F3N4O

  • Molecular Weight : 216.12

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PA 01 2921026

1-((3-Fluoro-4-(methylcarbamoyl)phenyl)(nitroso)amino)cyclobutane-1-carboxylic acid

1-((3-Fluoro-4-(methylcarbamoyl)phenyl)(nitroso)amino)cyclobutane-1-carboxylic acid

  • Catalogue No.:PA 01 2921026

  • CAS :

    NA

  • Molecular Formula : C13H14FN3O4

  • Molecular Weight : 295.27

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PA 01 2921027

2-Fluoro-N-methyl-4-(nitrosoamino)benzamide

2-Fluoro-N-methyl-4-(nitrosoamino)benzamide

  • Catalogue No.:PA 01 2921027

  • CAS :

    NA

  • Molecular Formula : C8H8FN3O2

  • Molecular Weight : 197.17

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PA 01 2921028

4-(N-(1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)formamido)-2-fluoro-N-methylbenzamide

4-(N-(1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)formamido)-2-fluoro-N-methylbenzamide

  • Catalogue No.:PA 01 2921028

  • CAS :

    NA

  • Molecular Formula : C21H17F4N5O3

  • Molecular Weight : 463.39

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