apixaban and its Impurities

Apixaban, sold under the trade name Eliquis among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation.. Reference standards of Apixaban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 45 results for apixaban Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 28 0111056

Apixaban Amino Acid Impurity Hydrochloride

Apixaban Amino Acid Impurity Hydrochloride

  • Catalogue No.:PA 28 0111056

  • CAS :

    2241139-69-3

  • Molecular Formula : C25H28ClN5O5

  • Molecular Weight : 513.98

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111058

6-(4-((5-Amino-5-oxopentyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

6-(4-((5-Amino-5-oxopentyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

  • Catalogue No.:PA 28 0111058

  • CAS :

    NA

  • Molecular Formula : C25H27N7O5

  • Molecular Weight : 505.54

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111059

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-5-carboxylic Acid

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-5-carboxylic Acid

  • Catalogue No.:PA 28 0111059

  • CAS :

    NA

  • Molecular Formula : C25H26N6O6

  • Molecular Weight : 506.52

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111060

1-(4-Methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(4-Methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

  • Catalogue No.:PA 28 0111060

  • CAS :

    NA

  • Molecular Formula : C29H34N6O5

  • Molecular Weight : 546.63

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111061

1-(3-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one

1-(3-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one

  • Catalogue No.:PA 28 0111061

  • CAS :

    2437650-75-2

  • Molecular Formula : C15H19N3O2

  • Molecular Weight : 273.34

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111062

1-(4-Aminophenyl)piperidin-2-one

1-(4-Aminophenyl)piperidin-2-one

  • Catalogue No.:PA 28 0111062

  • CAS :

    438056-68-9

  • Molecular Formula : C11H14N2O

  • Molecular Weight : 190.25

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111063

Ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazineylidene)acetate

Ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazineylidene)acetate

  • Catalogue No.:PA 28 0111063

  • CAS :

    473927-63-8

  • Molecular Formula : C11H13ClN2O3

  • Molecular Weight : 256.69

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111064

1-(4-Methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide

1-(4-Methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide

  • Catalogue No.:PA 28 0111064

  • CAS :

    NA

  • Molecular Formula : C25H27N7O5

  • Molecular Weight : 505.54

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111065

Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

  • Catalogue No.:PA 28 0111065

  • CAS :

    1801881-20-8

  • Molecular Formula : C27H28N4O5

  • Molecular Weight : 488.54

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111066

Ethyl 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

  • Catalogue No.:PA 28 0111066

  • CAS :

    1801881-21-9

  • Molecular Formula : C26H26N4O4

  • Molecular Weight : 458.52

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111067

5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)(nitroso)amino)pentanoic Acid

5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)(nitroso)amino)pentanoic Acid

  • Catalogue No.:PA 28 0111067

  • CAS :

    NA

  • Molecular Formula : C20H26N4O5

  • Molecular Weight : 402.45

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111068

5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide

5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide

  • Catalogue No.:PA 28 0111068

  • CAS :

    NA

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111069

6-(4-((4-Carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid

6-(4-((4-Carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid

  • Catalogue No.:PA 28 0111069

  • CAS :

    2264018-89-3

  • Molecular Formula : C25H26N4O6

  • Molecular Weight : 478.51

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111070

1-(4-Methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxylic Acid

1-(4-Methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxylic Acid

  • Catalogue No.:PA 28 0111070

  • CAS :

    NA

  • Molecular Formula : C25H26N4O6

  • Molecular Weight : 478.51

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111071

N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide

N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide

  • Catalogue No.:PA 28 0111071

  • CAS :

    NA

  • Molecular Formula : C16H19N3O3

  • Molecular Weight : 301.35

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111072

3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one

3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one

  • Catalogue No.:PA 28 0111072

  • CAS :

    NA

  • Molecular Formula : C20H27N3O3

  • Molecular Weight : 357.45

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111073

3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one

3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one

  • Catalogue No.:PA 28 0111073

  • CAS :

    NA

  • Molecular Formula : C20H27N3O3

  • Molecular Weight : 357.45

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111074

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

  • Catalogue No.:PA 28 0111074

  • CAS :

    2514951-00-7

  • Molecular Formula : C27H26N4O5

  • Molecular Weight : 486.53

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111075

3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

  • Catalogue No.:PA 28 0111075

  • CAS :

    NA

  • Molecular Formula : C20H25N3O3

  • Molecular Weight : 355.44

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111076

3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

  • Catalogue No.:PA 28 0111076

  • CAS :

    NA

  • Molecular Formula : C20H25N3O3

  • Molecular Weight : 355.44

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111077

1-(4-Methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide

1-(4-Methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide

  • Catalogue No.:PA 28 0111077

  • CAS :

    NA

  • Molecular Formula : C25H28N6O4

  • Molecular Weight : 476.54

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111078

6-(4-((4-Carboxybutyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid

6-(4-((4-Carboxybutyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid

  • Catalogue No.:PA 28 0111078

  • CAS :

    NA

  • Molecular Formula : C25H25N5O7

  • Molecular Weight : 507.5

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111079

5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)amino)pentanoic Acid

5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)amino)pentanoic Acid

  • Catalogue No.:PA 28 0111079

  • CAS :

    NA

  • Molecular Formula : C20H27N3O4

  • Molecular Weight : 373.45

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111080

Ethyl (((4-methoxyphenyl)imino)methylene)carbamate

Ethyl (((4-methoxyphenyl)imino)methylene)carbamate

  • Catalogue No.:PA 28 0111080

  • CAS :

    NA

  • Molecular Formula : C11H12N2O3

  • Molecular Weight : 220.23

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Drug Reference Standards & Impurity Synthesis in India
PA USP1040741

Apixaban (1040741)

Apixaban (1040741)

  • Catalogue No.:PA USP1040741

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111081

2,2,3,4-Tetramethylpentane

2,2,3,4-Tetramethylpentane

  • Catalogue No.:PA 28 0111081

  • CAS :

    1186-53-4

  • Molecular Formula : C9H20

  • Molecular Weight : 128.26

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111082

1-(2-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(2-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

  • Catalogue No.:PA 28 0111082

  • CAS :

    1801881-16-2

  • Molecular Formula : C25H25N5O4

  • Molecular Weight : 459.51

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111083

1-(3-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(3-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

  • Catalogue No.:PA 28 0111083

  • CAS :

    1801881-18-4

  • Molecular Formula : C25H25N5O4

  • Molecular Weight : 459.51

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111084

5-Bromo-4-methylpentanoyl Chloride

5-Bromo-4-methylpentanoyl Chloride

  • Catalogue No.:PA 28 0111084

  • CAS :

    140629-10-3

  • Molecular Formula : C6H10BrClO

  • Molecular Weight : 213.5

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111085

5-Bromo-4-methylpentanoic Acid

5-Bromo-4-methylpentanoic Acid

  • Catalogue No.:PA 28 0111085

  • CAS :

    89599-50-8

  • Molecular Formula : C6H11BrO2

  • Molecular Weight : 195.06

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111086

Diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydro-1,2,4,5-tetrazine-3,6-dicarboxylate

Diethyl 1,4-bis(4-methoxyphenyl)-1,4-dihydro-1,2,4,5-tetrazine-3,6-dicarboxylate

  • Catalogue No.:PA 28 0111086

  • CAS :

    132679-97-1

  • Molecular Formula : C22H24N4O6

  • Molecular Weight : 440.46

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111087

3-Morpholino-1-(3-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

3-Morpholino-1-(3-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

  • Catalogue No.:PA 28 0111087

  • CAS :

    2443747-50-8

  • Molecular Formula : C15H17N3O4

  • Molecular Weight : 303.32

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111088

1-(4-(2-Methyl-5-oxopyrrolidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one

1-(4-(2-Methyl-5-oxopyrrolidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one

  • Catalogue No.:PA 28 0111088

  • CAS :

    NA

  • Molecular Formula : C20H25N3O3

  • Molecular Weight : 355.44

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Drug Reference Standards & Impurity Synthesis in India
PA 28 0111089

Methyl 5-chloro-2-methylpentanoate

Methyl 5-chloro-2-methylpentanoate

  • Catalogue No.:PA 28 0111089

  • CAS :

    189046-69-3

  • Molecular Formula : C7H13ClO2

  • Molecular Weight : 164.63

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PA 28 0111090

5-Chloro-3-methyl-N-(4-nitrophenyl)-N-nitrosopentanamide

5-Chloro-3-methyl-N-(4-nitrophenyl)-N-nitrosopentanamide

  • Catalogue No.:PA 28 0111090

  • CAS :

    NA

  • Molecular Formula : C12H14ClN3O4

  • Molecular Weight : 299.71

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PA 28 0111091

N-Formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide

N-Formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide

  • Catalogue No.:PA 28 0111091

  • CAS :

    NA

  • Molecular Formula : C27H26N4O5

  • Molecular Weight : 486.53

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PA 28 0111092

Methyl 5-bromopentanoate

Methyl 5-bromopentanoate

  • Catalogue No.:PA 28 0111092

  • CAS :

    5454-83-1

  • Molecular Formula : C6H11BrO2

  • Molecular Weight : 195.06

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PA 28 0111093

5-Bromopentanoic acid

5-Bromopentanoic acid

  • Catalogue No.:PA 28 0111093

  • CAS :

    2067-33-6

  • Molecular Formula : C5H9BrO2

  • Molecular Weight : 181.03

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PA 28 0111094

Ethyl 1-(4-methoxyphenyl)-7a-morpholino-6-(4-nitrophenyl)-7-oxo-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 1-(4-methoxyphenyl)-7a-morpholino-6-(4-nitrophenyl)-7-oxo-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

  • Catalogue No.:PA 28 0111094

  • CAS :

    1620386-62-0

  • Molecular Formula : C26H29N5O7

  • Molecular Weight : 523.55

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PA 28 0111095

Dehydro Desmethoxy Apixaban

Dehydro Desmethoxy Apixaban

  • Catalogue No.:PA 28 0111095

  • CAS :

    NA

  • Molecular Formula : C24H21N5O3

  • Molecular Weight : 427.46

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PA 28 0111097

Ethyl 1-(4-hydroxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 1-(4-hydroxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

  • Catalogue No.:PA 28 0111097

  • CAS :

    NA

  • Molecular Formula : C21H18N4O6

  • Molecular Weight : 422.4

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PA 28 0111096

Ethyl 1-(4-hydroxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 1-(4-hydroxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

  • Catalogue No.:PA 28 0111096

  • CAS :

    NA

  • Molecular Formula : C21H18N4O6

  • Molecular Weight : 422.4

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PA 28 0111098

(2-Methoxyphenyl)hydrazine Hydrochloride

(2-Methoxyphenyl)hydrazine Hydrochloride

  • Catalogue No.:PA 28 0111098

  • CAS :

    6971-45-5

  • Molecular Formula : C7H11ClN2O

  • Molecular Weight : 174.63

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PA 28 0111099

1-(4-Methoxyphenyl)-N-methyl-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(4-Methoxyphenyl)-N-methyl-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

  • Catalogue No.:PA 28 0111099

  • CAS :

    NA

  • Molecular Formula : C26H27N5O4

  • Molecular Weight : 473.53

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PA 28 0111100

1-(4-Methoxyphenyl)-N-(1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbonyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(4-Methoxyphenyl)-N-(1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbonyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

  • Catalogue No.:PA 28 0111100

  • CAS :

    NA

  • Molecular Formula : C50H47N9O8

  • Molecular Weight : 901.98

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