Atropine sulfate and its Impurities

Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils.Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surgery. Reference standards of Atropine sulfate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.